Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency

Cancer Science

Volumn 101, Issue 12, 2010, Pages 2525-2530

  Tasaki, Masako ^a,b   Umemura, Takashi ^a   Suzuki, Yuta ^a   Hibi, Daisuke ^a   Inoue, Tomoki ^a   Okamura, Toshiya ^a   Ishii, Yuji ^a   Maruyama, Soichi ^b   Nohmi, Takehiko ^a   Nishikawa, Akiyoshi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b NIHON UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CYCLINE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; GENOMIC DNA; GLUTATHIONE TRANSFERASE; MESSENGER RNA; PHENOBARBITAL; PIPERONYL BUTOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME INDUCTION; GAM GENE; GENE MUTATION; GPT GENE; HEPATOMEGALY; IN VIVO STUDY; LIVER; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MALE; MUTAGENICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RED GENE; REPORTER GENE;

ANIMALS; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; DEOXYGUANOSINE; DNA DAMAGE; ESCHERICHIA COLI PROTEINS; GENES, REPORTER; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MUTATION; OXIDATIVE STRESS; PENTOSYLTRANSFERASES; PHENOBARBITAL; PIPERONYL BUTOXIDE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78449310291     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2010.01705.x     Document Type: Article

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