Analysis of the protein expression changes during taxol-induced apoptosis under translation inhibition conditions

Molecular and Cellular Biochemistry

Volumn 345, Issue 1-2, 2010, Pages 131-144

  Piñeiro, David ^a,b   González, Víctor M ^a   Salinas, Matilde ^a   Elena Martin M ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

Apoptosis; C Myc; Internal ribosome entry segment; Proteomics; Taxol; Translational control

Indexed keywords

CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DYSTROPHIN; MYC PROTEIN; PACLITAXEL;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL STRAIN HEK293; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEOMICS; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL CYCLE; CYTOSKELETAL PROTEINS; DYSTROPHIN; GENE EXPRESSION REGULATION; HUMANS; PACLITAXEL; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-MYC; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 78449292334     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0566-7     Document Type: Article

References (48)

1. EK Rowinsky 1997 The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents Annu Rev Med 48 353 374 10.1146/annurev.med.48.1.353 9046968
2. A Kienitz C Vogel I Morales R Muller H Bastians 2005 Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol Oncogene 24 4301 4310 10.1038/sj.onc.1208589 15782113
3. J Kelling K Sullivan L Wilson MA Jordan 2003 Suppression of centromere dynamics by Taxol in living osteosarcoma cells Cancer Res 63 2794 2801 12782584
4. H Xiao P Verdier-Pinard N Fernandez-Fuentes B Burd R Angeletti A Fiser SB Horwitz GA Orr 2006 Insights into the mechanism of microtubule stabilization by Taxol Proc Natl Acad Sci USA 103 10166 10173 10.1073/pnas.0603704103 16801540
5. PB Mullan JE Quinn PM Gilmore S McWilliams H Andrews C Gervin N McCabe S McKenna P White YH Song S Maheswaran E Liu DA Haber PG Johnston DP Harkin 2001 BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents Oncogene 20 6123 6131 10.1038/sj.onc.1204712 11593420
6. MA Jordan L Wilson 2004 Microtubules as a target for anticancer drugs Nat Rev Cancer 4 253 265 10.1038/nrc1317 15057285
7. BT McGrogan B Gilmartin DN Carney A McCann 2008 Taxanes, microtubules and chemoresistant breast cancer Biochim Biophys Acta 1785 96 132 18068131
8. TH Wang HS Wang YK Soong 2000 Paclitaxel-induced cell death: where the cell cycle and apoptosis come together Cancer 88 2619 2628 10.1002/1097- 0142(20000601)88:11<2619::AID-CNCR26>3.0.CO;2-J 10861441
9. LA Martello P Verdier-Pinard HJ Shen L He K Torres GA Orr SB Horwitz 2003 Elevated levels of microtubule destabilizing factors in a Taxol-resistant/ dependent A549 cell line with an alpha-tubulin mutation Cancer Res 63 1207 1213 12649178
10. GA Orr P Verdier-Pinard H McDaid SB Horwitz 2003 Mechanisms of Taxol resistance related to microtubules Oncogene 22 7280 7295 10.1038/sj.onc.1206934 14576838
11. P Verdier-Pinard F Wang L Martello B Burd GA Orr SB Horwitz 2003 Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry Biochemistry 42 5349 5357 10.1021/bi027293o 12731876
12. M Holcik N Sonenberg 2005 Translational control in stress and apoptosis Nat Rev Mol Cell Biol 6 318 327 10.1038/nrm1618 15803138
13. WE Marissen RE Lloyd 1998 Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells Mol Cell Biol 18 7565 7574 9819442
14. MJ Clemens M Bushell SJ Morley 1998 Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines Oncogene 17 2921 2931 10.1038/sj.onc.1202227 9879998
15. SJ Morley MJ Coldwell MJ Clemens 2005 Initiation factor modifications in the preapoptotic phase Cell Death Differ 12 571 584 10.1038/sj.cdd.4401591 15900314
16. CG Proud 2005 eIF2 and the control of cell physiology Semin Cell Dev Biol 16 3 12 10.1016/j.semcdb.2004.11.004 15659334
17. MJ Del Prete MS Robles A Guao AC Martinez M Izquierdo JA Garcia-Sanz 2002 Degradation of cellular mRNA is a general early apoptosis-induced event FASEB J 16 2003 2005 12397088
18. MJ Coldwell SA Mitchell M Stoneley M MacFarlane AE Willis 2000 Initiation of Apaf-1 translation by internal ribosome entry Oncogene 19 899 905 10.1038/sj.onc.1203407 10702798
19. M Holcik C Lefebvre C Yeh T Chow RG Korneluk 1999 A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection Nat Cell Biol 1 190 192 10.1038/11109 10559907
20. S Henis-Korenblit NL Strumpf D Goldstaub A Kimchi 2000 A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation Mol Cell Biol 20 496 506 10.1128/MCB.20.2.496-506.2000 10611228
21. M Stoneley FE Paulin JP Le Quesne SA Chappell AE Willis 1998 C-Myc 5′ untranslated region contains an internal ribosome entry segment Oncogene 16 423 428 10.1038/sj.onc.1201763 9467968
22. A Wolf-Yadlin M Sevecka G MacBeath 2009 Dissecting protein function and signaling using protein microarrays Curr Opin Chem Biol 13 398 405 10.1016/j.cbpa.2009.06.027 19660979
23. E Martinez-Salas R Ramos E Lafuente S Lopez de Quinto 2001 Functional interactions in internal translation initiation directed by viral and cellular IRES elements J Gen Virol 82 973 984 11297672
24. R Ramos E Martinez-Salas 1999 Long-range RNA interactions between structural domains of the aphthovirus internal ribosome entry site (IRES) RNA 5 1374 1383 10.1017/S1355838299991240 10573128
25. ME Martin FM Munoz M Salinas JL Fando 2000 Ischaemia induces changes in the association of the binding protein 4E-BP1 and eukaryotic initiation factor (eIF) 4G to eIF4E in differentiated PC12 cells Biochem J 351 Pt 2 327 334 10.1042/0264-6021:3510327 11023817
26. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3 942051
27. ME Martin A Alcazar JL Fando AM Garcia M Salinas 1993 Translational initiation factor eIF-2 subcellular levels and phosphorylation status in the developing rat brain Neurosci Lett 156 109 112 10.1016/0304-3940(93)90451-P 7692359
28. C Cid JC Alvarez-Cermeno I Regidor J Plaza M Salinas A Alcazar 2003 Caspase inhibitors protect against neuronal apoptosis induced by cerebrospinal fluid from multiple sclerosis patients J Neuroimmunol 136 119 124 10.1016/S0165-5728(02)00467-8 12620650
29. D Pineiro VM Gonzalez M Hernandez-Jimenez M Salinas ME Martin 2007 Translation regulation after taxol treatment in NIH3T3 cells involves the elongation factor (eEF)2 Exp Cell Res 313 3694 3706 10.1016/j.yexcr.2007.07.025 17825817
30. E Martinez-Salas JC Saiz M Davila GJ Belsham E Domingo 1993 A single nucleotide substitution in the internal ribosome entry site of foot-and-mouth disease virus leads to enhanced cap-independent translation in vivo J Virol 67 3748 3755 8389904
31. MacGregor GR, Nolan GP, Fiering S, Roederer M, Herzenberg LA (1991) Use of E. coli lacZ (β-Galactosidase) as a reporter gene. In: Murray EJ, Walker JM (eds) Methods in molecular biology. Humana, Clifton, NJ, pp 217-235
32. M Morita H Suyama T Igishi Y Shigeoka M Kodani K Hashimoto K Takeda T Sumikawa E Shimizu 2007 Dexamethasone inhibits paclitaxel-induced cytotoxic activity through retinoblastoma protein dephosphorylation in non-small cell lung cancer cells Int J Oncol 30 187 192 17143528
33. H Suyama T Igishi H Sano S Matsumoto Y Shigeoka H Nakanishi M Endo N Burioka Y Hitsuda E Shimizu 2004 ERK activation and subsequent RB phosphorylation are important determinants of the sensitivity to paclitaxel in lung adenocarcinoma cells Int J Oncol 24 1499 1504 15138593
34. SD Baird M Turcotte RG Korneluk M Holcik 2006 Searching for IRES RNA 12 1755 1785 10.1261/rna.157806 16957278
35. Mokrejs M, Masek T, Vopalensky V, Hlubucek P, Delbos P, Pospisek M (2010) IRESite-a tool for the examination of viral and cellular internal ribosome entry sites. Nucl Acids Res 38: D131-D136
36. JK Park YM Chung S Kang JU Kim YT Kim HJ Kim YH Kim JS Kim YD Yoo 2002 c-Myc exerts a protective function through ornithine decarboxylase against cellular insults Mol Pharmacol 62 1400 1408 10.1124/mol.62.6.1400 12435808
37. G Lubec K Krapfenbauer M Fountoulakis 2003 Proteomics in brain research: potentials and limitations Prog Neurobiol 69 193 211 10.1016/S0301-0082(03) 00036-4 12758110
38. A Bayes SG Grant 2009 Neuroproteomics: understanding the molecular organization and complexity of the brain Nat Rev Neurosci 10 635 646 10.1038/nrn2701 19693028
39. Wolf-Yadlin A, Sevecka M, Macbeath G (2009) Dissecting protein function and signaling using protein microarrays. Curr Opin Chem Biol
40. G Shaw S Morse M Ararat FL Graham 2002 Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells FASEB J 16 869 871 11967234
41. AR Jazirehi XH Gan S De Vos C Emmanouilides B Bonavida 2003 Rituximab (anti-CD20) selectively modifies Bcl-xL and apoptosis protease activating factor-1 (Apaf-1) expression and sensitizes human non-Hodgkin's lymphoma B cell lines to paclitaxel-induced apoptosis Mol Cancer Ther 2 1183 1193 14617792
42. CM Eischen G Packham J Nip BE Fee SW Hiebert GP Zambetti JL Cleveland 2001 Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 Oncogene 20 6983 6993 10.1038/sj.onc.1204892 11704823
43. Z You LV Madrid D Saims J Sedivy CY Wang 2002 c-Myc sensitizes cells to tumor necrosis factor-mediated apoptosis by inhibiting nuclear factor kappa B transactivation J Biol Chem 277 36671 36677 10.1074/jbc.M203213200 12149248
44. WJ Li YY Gu HJ Zhang J Zhou HT Jia 2009 Induction of p14ARF by E2F1 contributes to 8-chloro-adenosine-induced apoptosis in human lung cancer H1299 cells Chemotherapy 55 335 343 10.1159/000230697 19641316
45. R Drago-Ferrante A Santulli R Di Fiore M Giuliano G Calvaruso G Tesoriere R Vento 2008 Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1 Int J Oncol 33 677 687 18813780
46. M Stoneley SA Chappell CL Jopling M Dickens M MacFarlane AE Willis 2000 c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis Mol Cell Biol 20 1162 1169 10.1128/MCB.20.4.1162-1169.2000 10648601
47. SR Hann RN Eisenman 1984 Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells Mol Cell Biol 4 2486 2497 6513926
48. AR Williams J Piris AH Wyllie 1990 Immunohistochemical demonstration of altered intracellular localization of the C-Myc oncogene product in human colorectal neoplasms J Pathol 160 287 293 10.1002/path.1711600404 2193134