The role of serum D-dimer level in the diagnosis of patients admitted to the emergency department complaining of chest pain

Journal of International Medical Research

Volumn 38, Issue 5, 2010, Pages 1772-1779

  Orak, M ^a   Ustundag M ^a   Guloglu C ^a   Alyan, O ^a   Sayhan, M B ^b  

^a DICLE UNIVERSITY   (Turkey)

^b State Hospital   (Turkey)

Author keywords

Acute coronary syndrome; Angina pectoris; Chest pain; D dimer; Diagnosis; Emergency department; Mortality; Myocardial infarction

Indexed keywords

CREATINE KINASE MB; D DIMER; TROPONIN I;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIAGNOSTIC VALUE; EMERGENCY WARD; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THORAX PAIN; UNSTABLE ANGINA PECTORIS;

EID: 78449291502     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800523     Document Type: Article

References (25)

1. Bayes-Genis A, Mateo J, Santalo M, et al: D-dimer is an early diagnostic marker of coronary ischemia in patients with chest pain. Am Heart J 2000; 140: 379-384.
2. Rude RE, Poole WK, Muller JE, et al: Electrocardiographic and clinical criteria for recognition of acute myocardial infarction based on analysis of 3,697 patients. Am J Cardiol 1983; 52: 936-942.
3. Bakker AJ, Koelemay MJ, Gorgels JP, et al: Failure of new biochemical markers to exclude acute myocardial infarction at admission. Lancet 1993; 342: 1220-1222.
4. Norell M, Lythall D, Goghlan G, et al: Limited value of the resting electrocardiogram in assessing patients with recent onset chest pain: lessons from a chest pain clinic. Br Heart J 1992; 67: 53-56.
5. Shitrit AB, Tzivony D, Shilon Y, et al: The role of enzyme-linked immunosorbent assay D-dimer in patients with acute coronary syndrome presenting with normal cardiac enzymes. Blood Coagul Fibrinolysis 2006; 17: 621-624.
6. Hunt FA, Rylatt DB, Hart RA, et al: Serum cross-linked fibrin and fibrinogen/fibrin degradation products in disorders associated with activation of the coagulation or fibrinolytic systems. Br J Haematol 1985; 60: 715-722.
7. Shitrit D, Bar-Gil Shitrit A, Rudensky B, et al: Role of ELISA D-dimer test in patients with unstable angina pectoris presenting at the emergency department with a normal electrocardiogram. Am J Hematol 2004; 77: 147-150.
8. Pollack CV Jr, Roe MT, Peterson ED: 2002 update to the ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: implications for emergency department practice. Ann Emerg Med 2003; 41: 355-369.
9. Green BG, Hill PM: Approach to chest pain. In: Emergency Medicine: a Comprehensive Study Guide, 6th edn (Tintinalli JE, Kelen GD, Stapczynski JS, eds). New York: McGraw-Hill Professional, 2004; pp 333-342.
10. Hlatky MA: Evaluation of chest pain in the emergency department. N Engl J Med 1997; 337: 1687-1689.
11. Lee TH, Rouan GW, Weisberg MC, et al: Sensitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization. Ann Intern Med 1987; 106: 181-186.
12. Gibler WB, Young GP, Hedges JR, et al: Acute myocardial infarction in chest pain patients with nondiagnostic ECGs: serial CK-MB sampling in the emergency department. The Emergency Medicine Cardiac Research Group. Ann Emerg Med 1992; 21: 504-512.
13. Brush JE Jr, Brand DA, Acampora D, et al: Use of the initial electrocardiogram to predict in-hospital complications of acute myocardial infarction. N Engl J Med 1985; 312: 1137-1141.
14. Rouan GW, Lee TH, Cook EF, et al: Clinical characteristics and outcome of acute myocardial infarction in patients with initially normal or nonspecific electrocardiograms (a report from the Multicenter Chest Pain Study). Am J Cardiol 1989; 64: 1087-1092.
15. Pozen MW, D'Agostino RB, Selker HP, et al: A predictive instrument to improve coronary-care-unit admission practices in acute ischemic heart disease: a prospective multicenter clinical trial. N Engl J Med 1984; 310: 1273-1278.
16. Rao KM, Pieper CS, Currie MS, et al: Variability of plasma IL-6 and cross-linked fibrin dimers over time in community dwelling elderly subjects. Am J Clin Pathol 1994; 102: 802-805.
17. Bounameaux H, Schneider PA, Reber G, et al: Measurement of plasma D-dimer for diagnosis of deep venous thrombosis. Am J Clin Pathol 1989; 91: 82-85.
18. Bounameaux H, Cirafici P, de Moerloose P, et al: Measurement of D-dimer in plasma as diagnostic aid in suspected pulmonary embolism. Lancet 1991; 337: 196-200.
19. Kruskal JB, Commerford PJ, Franks JJ, et al: Fibrin and fibrinogen-related antigens in patients with stable and unstable coronary artery disease. N Engl J Med 1987; 317: 1361-1365.
20. Francis CW, Connaghan DG, Scott WL, et al: Increased plasma concentration of cross-linked fibrin polymers in acute myocardial infarction. Circulation 1987; 75: 1170-1177.
21. Lee LV, Ewald GA, McKenzie CR, et al: The relationship of soluble fibrin and cross-linked fibrin degradation products to the clinical course of myocardial infarction. Arterioscl Thromb Vasc Biol 1997; 17: 628-633.
22. Gurfinkel E, Bozovich G, Cerdá M, et al: Time significance of acute thrombotic reactant markers in patients with and without silent myocardial ischemia and overt unstable angina pectoris. Am J Cardiol 1995; 76: 121-124.
23. Ieko M, Naito S, Yoshida M, et al: Plasma soluble fibrin monomer complex as a marker of coronary thrombotic events in patients with acute myocardial infarction. Tohoku J Exp Med 2009; 219: 25-31.
24. Figueras J, Monasterio Y, Lidón RM, et al: Thrombin formation and fibrinolytic activity in patients with acute myocardial infarction or unstable angina: in-hospital course and relationship with recurrent angina at rest. J Am Coll Cardiol 2000; 36: 2036-2043.
25. Oldgren J, Linder R, Grip L, et al: Coagulation activity and clinical outcome in unstable coronary artery disease. Arterioscler Thromb Vasc Biol 2001; 21: 1059-1064.