A cost analysis of photodynamic therapy with methyl aminolevulinate and imiquimod compared with conventional surgery for the treatment of superficial basal cell carcinoma and Bowen's disease of the lower extremities

Journal of the European Academy of Dermatology and Venereology

Volumn 24, Issue 12, 2010, Pages 1431-1436

  Aguilar, M ^a   De Troya, M ^a   Martin, L ^a   Benitez N ^a   Gonzalez M ^a  

^a HOSPITAL COSTA DEL SOL   (Spain)

Author keywords

analysis; cost analysis; imiquimod; methyl aminolevulinate photodynamic therapy; retrospective study; surgery

Indexed keywords

AMINOLEVULINIC ACID METHYL ESTER; IMIQUIMOD;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; BOWEN DISEASE; COST BENEFIT ANALYSIS; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; LEG; MAJOR CLINICAL STUDY; MALE; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SKIN SURGERY; TREATMENT RESPONSE;

AMINOLEVULINIC ACID; AMINOQUINOLINES; BOWEN'S DISEASE; CARCINOMA, BASAL CELL; COST-BENEFIT ANALYSIS; HUMANS; PHOTOCHEMOTHERAPY; SKIN NEOPLASMS;

EID: 78449285801     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2010.03664.x     Document Type: Article

References (18)

1. Ellis CN, Reiter KL, Wheeler JR, et al. Economic analysis in dermatology. J Am Acad Dermatol 2002; 46: 271-283.
2. Buhler-Singer S, Hiller D, Albrecht HP, et al. Disturbances of cutaneous microcirculation in patients with diabetic legs: additional parameters for a new therapeutic concept? Acta Derm Venereol 1994; 74: 250-256.
3. Tallon B, Lamb S, Patel D,. Randomized nonblinded comparison of convalescence for 2 and 7 days after split-thickness skin grafting to the lower legs. Dermatol Surg 2009; 35: 634-637.
4. Coldiron BM, Rivera E,. Delayed full-thickness grafting of lower leg defects following removal of skin malignancies. Dermatol Surg 1996; 22: 23-26.
5. Gerritsen MJ, De Rie MA, Beljaards RC, et al. Survey among patients with basal cell carcinoma in The Netherlands. J Dermatolog Treat 2009; 1: 1-6.
6. Higashi MK, Veenstra DL, Langley PC,. Health economic evaluation of non-melanoma skin cancer and actinic keratosis. Pharmacoeconomics 2004; 22: 83-94.
7. Braathen LR, Szeimies RM, Basset-Seguin N, et al. Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005. J Am Acad Dermatol 2007; 56: 125-143.
8. Karve SJ, Feldman SR, Yentzer BA, et al. Imiquimod: a review of basal cell carcinoma treatments. J Drugs Dermatol 2008; 7: 1044-1051.
9. Annemans L, Caekelbergh K, Roelandts R, et al. Real-life practice study of the clinical outcome and cost-effectiveness of photodynamic therapy using methyl aminolevulinate (MAL-PDT) in the management of actinic keratosis and basal cell carcinoma. Eur J Dermatol 2008; 18: 539-546.
10. Caekelbergh K, Annemans L, Lambert J, et al. Economic evaluation of methyl aminolaevulinate-based photodynamic therapy in the management of actinic keratosis and basal cell carcinoma. Br J Dermatol 2006; 155: 784-790.
11. Vanaclocha F, Dauden E, Badia X, et al. Cost-effectiveness of treatment of superficial basal cell carcinoma: surgical excision vs. imiquimod 5% cream. Br J Dermatol 2007; 156: 769-771.
12. Carpenter J, Bithell J,. Bootstrap confidence intervals: when, which, what? A practical guide for medical statisticians. Stat Med 2000; 19: 1141-1164.
13. Clayton TH, Tait J, Whitehurst C, et al. Photodynamic therapy for superficial basal cell carcinoma and Bowen's disease. Eur J Dermatol 2006; 16: 39-41.
14. Morton CA, Brown SB, Collins S, et al. Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group. Br J Dermatol 2002; 146: 552-567.
15. Gollnick H, Barona CG, Frank RG, et al. Recurrence rate of superficial basal cell carcinoma following treatment with imiquimod 5% cream: conclusion of a 5-year long-term follow-up study in Europe. Eur J Dermatol 2008; 18: 677-682.
16. Roberts RR, Frutos PW, Ciavarella GG, et al. Distribution of variable vs. fixed costs of hospital care. JAMA 1999; 281: 644-649.
17. Weston A, Fitzgerald P,. Discrete choice experiment to derive willingness to pay for methyl aminolevulinate photodynamic therapy versus simple excision surgery in basal cell carcinoma. Pharmacoeconomics 2004; 22: 1195-1208.
18. Asgari MM, Bertenthal D, Sen S, et al. Patient satisfaction after treatment of nonmelanoma skin cancer. Dermatol Surg 2009; 35: 1041-1049.