Opportunistic disorders of the gastrointestinal tract in the age of highly active antiretroviral therapy

Human Pathology

Volumn 41, Issue 12, 2010, Pages 1777-1787

  Huppmann, Alison R ^a   Orenstein, Jan Marc ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Gastrointestinal; HAART; HIV AIDS; Opportunistic infections

Indexed keywords

ADENOVIRUS; ARTICLE; CANDIDA; COLON; CRYPTOCOCCUS; CRYPTOSPORIDIUM; CYTOMEGALOVIRUS; DIGESTIVE SYSTEM ULCER; ENTEROPATHOGENIC ESCHERICHIA COLI INFECTION; ESOPHAGUS BIOPSY; ESOPHAGUS CANDIDIASIS; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL CARCINOMA; GASTROINTESTINAL ENDOSCOPY; GASTROINTESTINAL INFECTION; GIARDIA; HELICOBACTER PYLORI; HERPES SIMPLEX VIRUS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN TISSUE; ISOSPORA; KAPOSI SARCOMA; LYMPHOID HYPERPLASIA; MAJOR CLINICAL STUDY; MICROSPORIDIOSIS; MYCOBACTERIUM INTRACELLULARE AVIUM; NONHODGKIN LYMPHOMA; OPPORTUNISTIC INFECTION; PSEUDOMEMBRANOUS COLITIS; RECTUM; RECTUM BIOPSY; SMALL INTESTINE; SPIROCHETE INFECTION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; COMORBIDITY; DISTRICT OF COLUMBIA; ENDOSCOPY, GASTROINTESTINAL; GASTROINTESTINAL DISEASES; HUMANS;

EID: 78449273484     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2010.06.007     Document Type: Article

References (31)

1. + T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy J Virol 77 2003 11708 11717
2. + T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract J Exp Med 200 2004 149 159
3. + T lymphocytes from effector sites in the gastrointestinal tract J Exp Med 200 2004 761 770
4. + T-cell depletion during acute and early human immunodeficiency virus type 1 infection J Virol 81 2007 599 612 (Pubitemid 46067887)
5. Orenstein J.M. HIV expression in surgical specimens AIDS Res Hum Retroviruses 24 2008 947 955
6. Silver S., Wahl S.M., Orkin B.A., and Orenstein J.M. Changes in circulating levels of HIV, CD4, and tissue expression of HIV in a patient with recent onset ulcerative colitis treated by surgery: a case report J Hum Virol 2 1999 52 57
7. Kotler D.P., Reka S., Orenstein J.M., and Fox C.F. Chronic idiopathic esophageal ulceration in the acquired immunodeficiency syndrome: characterization and treatment with corticosteroids J Clin Gastroenterol 15 1992 284 290
8. Johnson L., Jarvis J.N., Wilkins E.G.L., and Hay P.E. Thalidomide treatment for refractory HIV-associated colitis: a case series CID 47 2008 133 136
9. Orenstein J.M. The role of electron microscopy in infectious disease diagnosis J Histotech 18 1995 211 224
10. Orenstein J.M. Ultrastructure of HIV/AIDS Ultrastruct Pathol 26 2002 245 250
11. Smith P.D., Saini S.S., and Orenstein J.M. Infections of the large intestine in the immunocompromised host S.F. Phillips, J.H. Pemberton, R.G. Shorter, The large intestine: physiology, pathophysiology, and disease 1991 437 444
12. Orenstein J.M., and Dieterich D.T. The histopathology of 103 consecutive colonoscopy biopsies from 82 symptomatic patients with acquired immunodeficiency syndrome Arch Pathol Lab Med 125 2001 1042 1046
13. Romanelli F., Smith K.M., and Murphy B.S. Does HIV infection alter the incidence or pathology of Helicobacter pylori infection? AIDS Patient Care STDs 21 2007 908 919
14. Janoff E.N., Orenstein J.M., Manischewitz J.F., and Smith P.D. Adenovirus colitis in the acquired immunodeficiency syndrome Gastroenterology 100 1991 976 979
15. Benator D.A., French A.L., Beaudet L.M., Levy C.S., and Orenstein J.M. Isospora belli infection associated with acalculous cholecystitis in a patient with AIDS Ann Intern Med 121 1994 663 664
16. Kotler D.P., and Orenstein J.M. Chronic diarrhea and malabsorption associated with enteropathogenic bacterial infection in a patient with AIDS Ann Int Med 119 1993 127 128
17. Kotler D.P., Giang T.T., and Thiim M. Chronic bacterial enteropathy in patients with AIDS J Infect Dis 171 1995 552 558
18. Orenstein J.M., and Kotler D.P. Diarrheogenic bacterial enteritis in acquired immunodeficiency syndrome: a light and electron microscopy study of 52 cases Hum Pathol 26 1995 481 492
19. Orenstein J.M., Chiang J., and Steinberg W. Intestinal microsporidiosis as a cause of diarrhea in human immunodeficiency virus-infected patients: a report of 20 cases Hum Pathol 21 1990 475 481
20. Orenstein J.M. Microsporidiosis in the acquired immunodeficiency syndrome J Parasitol 77 1991 843 864
21. Cali A., Kotler D.P., and Orenstein J.M. Septata intestinalis, N.G., N.SP, an intestinal microsporidian associated with chronic diarrhea and dissemination in AIDS patients J Euk Microbiol 40 1993 101 112
22. Shadduck J.A., and Orenstein J.M. Comparative pathology of microsporidiosis Arch Pathol Lab Med 117 1993 1215 1219
23. Orenstein J.M., Dieterich D.T., and Kotler D.R. Biopsy diagnosis of intestinal microsporidiosis AIDS 7 Suppl 3 1993 S49 S54
24. Kotler D.P., Giang T.T., Garro M.L., and Orenstein J.M. Light microscopic diagnosis of microsporidiosis in patients with AIDS Amer J Gastroenterol 89 1994 540 544
25. Orenstein J.M. Diagnostic pathology of microsporidiosis Ultrastruct Pathol 27 2003 141 149
26. Soule J.B., Halverson A.L., and Becker R.B. A patient with acquired immunodeficiency syndrome and untreated Encephalitozoon (Septata) intestinalis microsporidiosis leading to small bowel perforation. Response to albendazole Arch Pathol Lab Med 121 1997 880 887
27. Orenstein J.M., Tenner M., and Kotler D.P. Localization of infection by the microsporidian Enterocytozoon bieneusi in the gastrointestinal tract of AIDS patients with diarrhea AIDS 6 1992 195 197
28. Orenstein J.M., Alkan S., and Blauvelt A. Visualization of human herpesvirus in Kaposi's sarcoma by light and transmission electron microscopy AIDS 11 1997 F35 F45
29. Batman P.A., Kotler D.P., and Kapembwa M.S. HIV enteropathy: increased proliferation in stem cells and transit cells induces crypt hyperplastic villous atrophy in HIV/microsporidia-infected jejunal mucosa AIDS 21 2007 433 439
30. Poles M.A., Boscardin W.J., and Elliott J. Lack of decay of HIV-1 in gut-associated lymphoid tissue reservoirs in maximally suppressed individuals J Acquir Immune Defic Syndr 43 2006 65 68
31. Monkemüller KE Lazenby A.J., and Lee D.H. Occurrence of gastrointestinal opportunistic disorders in AIDS despite the use of highly active antiretroviral therapy Dig Dis Sci 50 2005 230 234