Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution

Journal of Biological Chemistry

Volumn 285, Issue 47, 2010, Pages 36456-36470

  Bontjer, Ilja ^a   Melchers, Mark ^a   Eggink, Dirk ^a   David, Kathryn ^b   Moore, John P ^b   Berkhout, Ben ^a   Sanders, Rogier W ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE GLYCOPROTEINS; HUMORAL IMMUNITY; HYDROPHOBIC PATCH; HYDROPHOBIC RESIDUES; HYDROPHOBIC SURFACES; IMMUNOGENICITY; NEUTRALIZING ANTIBODIES; PROTEIN MISFOLDING; STRUCTURAL STUDIES; VACCINE DEVELOPMENT; VARIABLE DOMAIN;

ANTIBODIES; CARBOHYDRATES; DISEASES; GLYCOPROTEINS; HYDROPHOBICITY; SURFACE CHEMISTRY;

VIRUSES;

EPITOPE; GLYCAN; GLYCOPROTEIN GP 140; NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; GENE DELETION; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHILICITY; HYDROPHOBICITY; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; VIROGENESIS; VIRUS ISOLATION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; DIRECTED MOLECULAR EVOLUTION; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV ANTIBODIES; HIV ANTIGENS; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NEUTRALIZATION TESTS; POLYSACCHARIDES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; PAXTON;

EID: 78449241664     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.156588     Document Type: Article

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