-
1
-
-
37049000817
-
Randomized adjuvant therapy trials in melanoma: Surgical and systemic
-
A.M. Eggermont, and M. Gore Randomized adjuvant therapy trials in melanoma: surgical and systemic Semin Oncol 34 2007 509 515
-
(2007)
Semin Oncol
, vol.34
, pp. 509-515
-
-
Eggermont, A.M.1
Gore, M.2
-
2
-
-
3843113670
-
Re-evaluating the role of dacarbazine in metastatic melanoma: What have we learned in 30 years?
-
A.M. Eggermont, and J.M. Kirkwood Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years? Eur J Cancer 40 2004 1825 1836
-
(2004)
Eur J Cancer
, vol.40
, pp. 1825-1836
-
-
Eggermont, A.M.1
Kirkwood, J.M.2
-
3
-
-
0037108861
-
Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: Results of a randomized trial
-
P. Hersey, A.S. Coates, and W.H. McCarthy Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: results of a randomized trial J Clin Oncol 20 2002 4181 4190
-
(2002)
J Clin Oncol
, vol.20
, pp. 4181-4190
-
-
Hersey, P.1
Coates, A.S.2
McCarthy, W.H.3
-
4
-
-
0037089687
-
Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Overall results of a randomized trial of the Southwest Oncology Group
-
V.K. Sondak, P.Y. Liu, and R.J. Tuthill Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group J Clin Oncol 20 2002 2058 2066
-
(2002)
J Clin Oncol
, vol.20
, pp. 2058-2066
-
-
Sondak, V.K.1
Liu, P.Y.2
Tuthill, R.J.3
-
5
-
-
78449262515
-
Ten-year analysis of vaccinia melanoma oncolysate (VMO) phase III trial
-
M.K. Wallack, M. Berenji, K. Alam, and A.A. Bartolucci Ten-year analysis of vaccinia melanoma oncolysate (VMO) phase III trial [abstract 19031] J Clin Oncol 28 Suppl 2010
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Wallack, M.K.1
Berenji, M.2
Alam, K.3
Bartolucci, A.A.4
-
6
-
-
34548249596
-
An international, randomised, phase III trial of BCG plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional nodes or distant sites
-
D. Morton, N. Mozzillo, and J. Thompson An international, randomised, phase III trial of BCG plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional nodes or distant sites [abstract] J Clin Oncol 25 Suppl 2007 8508
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
, pp. 8508
-
-
Morton, D.1
Mozzillo, N.2
Thompson, J.3
-
7
-
-
0035339880
-
High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: Results of intergroup trial E1694/S9512/C509801
-
J.M. Kirkwood, J.G. Ibrahim, and J.A. Sosman High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801 J Clin Oncol 19 2001 2370 2380
-
(2001)
J Clin Oncol
, vol.19
, pp. 2370-2380
-
-
Kirkwood, J.M.1
Ibrahim, J.G.2
Sosman, J.A.3
-
8
-
-
58849101306
-
EORTC 18961: Post-operative adjuvant ganglioside GM2-KLH21 vaccination treatment vs observation in stage II (T3-T4N0M0) melanoma: 2nd interim analysis led to an early disclosure of the results
-
A.M. Eggermont, S. Suciu, and W. Ruka EORTC 18961: post-operative adjuvant ganglioside GM2-KLH21 vaccination treatment vs observation in stage II (T3-T4N0M0) melanoma: 2nd interim analysis led to an early disclosure of the results [abstract] J Clin Oncol 26 Suppl 2008 9004
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
, pp. 9004
-
-
Eggermont, A.M.1
Suciu, S.2
Ruka, W.3
-
9
-
-
67650938101
-
Therapeutic vaccines in solid tumours: Can they be harmful?
-
A.M.M. Eggermont Therapeutic vaccines in solid tumours: can they be harmful? Eur J Cancer 45 2009 2087 2090
-
(2009)
Eur J Cancer
, vol.45
, pp. 2087-2090
-
-
Eggermont, A.M.M.1
-
10
-
-
78449263060
-
Randomized phase III trial comparing postoperative adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation in stage II (T3-T4N0M0) melanoma: Final results of study EORTC 18961
-
A.M.M. Eggermont, S. Suciu, and P. Rutkowski Randomized phase III trial comparing postoperative adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation in stage II (T3-T4N0M0) melanoma: final results of study EORTC 18961 [abstract 8505] J Clin Oncol 28 Suppl 2010
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Eggermont, A.M.M.1
Suciu, S.2
Rutkowski, P.3
-
11
-
-
78449242173
-
E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage III-IV melanoma
-
D.H. Lawson, S.J. Lee, A.A. Tarhini, K.A. Margolin, M.S. Ernstoff, and J.M. Kirkwood E4697: phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage III-IV melanoma [abstract 8504] J Clin Oncol 28 Suppl 2010
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Lawson, D.H.1
Lee, S.J.2
Tarhini, A.A.3
Margolin, K.A.4
Ernstoff, M.S.5
Kirkwood, J.M.6
-
12
-
-
72549086588
-
Impact of GM-CSF on vaccination with an allogeneic whole-cell melanoma vaccine
-
M.B. Faries, E.C. Hsueh, X. Ye, M. Hoban, and D.L. Morton Impact of GM-CSF on vaccination with an allogeneic whole-cell melanoma vaccine Clin Cancer Res 15 2009 7029 7035
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7029-7035
-
-
Faries, M.B.1
Hsueh, E.C.2
Ye, X.3
Hoban, M.4
Morton, D.L.5
-
13
-
-
72549116845
-
Effect of GM-CSF on circulating CD8+ and CD4+ T cell responses to a multipeptide melanoma vaccine: Outcome of a multicenter randomized trial
-
C.L. Slingluff, G.R. Pettron, and W. Cison Effect of GM-CSF on circulating CD8+ and CD4+ T cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trial Clin Cancer Res 15 2009 7036 7044
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7036-7044
-
-
Slingluff, C.L.1
Pettron, G.R.2
Cison, W.3
-
14
-
-
72549108633
-
Immunostimulation versus immunosuppression after multiple vaccinations: The woes of therapeutic vaccine development
-
A.M.M. Eggermont Immunostimulation versus immunosuppression after multiple vaccinations: the woes of therapeutic vaccine development Clin Cancer Res 15 2009 6745 6747
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6745-6747
-
-
Eggermont, A.M.M.1
-
15
-
-
0034777045
-
The role interferon-alpha in malignant melanoma remains to be defined
-
A.M.M. Eggermont The role interferon-alpha in malignant melanoma remains to be defined Eur J Cancer 37 2001 2147 2153
-
(2001)
Eur J Cancer
, vol.37
, pp. 2147-2153
-
-
Eggermont, A.M.M.1
-
16
-
-
0028872887
-
Randomized, surgical adjuvant clinical trial of recombinant interferon alfa-2a in selected patients with malignant melanoma
-
E.T. Creagan, R.J. Dalton, and D.L. Ahmann Randomized, surgical adjuvant clinical trial of recombinant interferon alfa-2a in selected patients with malignant melanoma J Clin Oncol 13 1995 2776 2783
-
(1995)
J Clin Oncol
, vol.13
, pp. 2776-2783
-
-
Creagan, E.T.1
Dalton, R.J.2
Ahmann, D.L.3
-
17
-
-
0030030347
-
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group trial EST 1684
-
J.M. Kirkwood, M.H. Strawderman, M.S. Ernstoff, T.J. Smith, E.C. Borden, and R.H. Blum Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group trial EST 1684 J Clin Oncol 14 1996 7 17
-
(1996)
J Clin Oncol
, vol.14
, pp. 7-17
-
-
Kirkwood, J.M.1
Strawderman, M.H.2
Ernstoff, M.S.3
Smith, T.J.4
Borden, E.C.5
Blum, R.H.6
-
18
-
-
0034088027
-
High- and low-dose interferon alfa-2b in high-risk melanoma: First analysis of intergroup trial E1690/S9111/C9190
-
J.M. Kirkwood, J.G. Ibrahim, and V.K. Sondak High- and low-dose interferon alfa-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190 J Clin Oncol 18 2000 2444 2459
-
(2000)
J Clin Oncol
, vol.18
, pp. 2444-2459
-
-
Kirkwood, J.M.1
Ibrahim, J.G.2
Sondak, V.K.3
-
20
-
-
25844465690
-
Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): Randomised controlled trial
-
A.M. Eggermont, S. Suciu, and R. MacKie Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial Lancet 366 2005 1189 1196
-
(2005)
Lancet
, vol.366
, pp. 1189-1196
-
-
Eggermont, A.M.1
Suciu, S.2
MacKie, R.3
-
21
-
-
67650784545
-
Results of the Nordic radomized adjuvant trial of intermediate-doe interferon alfa-2b in high-risk melanoma
-
J. Hansson, S. Aamdal, L. Bastholt, M. Hernberg, B. Nilsson, U. Stierner, and H. von der Maase Results of the Nordic radomized adjuvant trial of intermediate-doe interferon alfa-2b in high-risk melanoma [abstract 4] Eur J Cancer 5 Suppl 2007
-
(2007)
Eur J Cancer
, vol.5
, Issue.SUPPL.
-
-
Hansson, J.1
Aamdal, S.2
Bastholt, L.3
Hernberg, M.4
Nilsson, B.5
Stierner, U.6
Von Der Maase, H.7
-
22
-
-
7144228601
-
Randomised trial of interferon alpha-2a as adjuvant therapy in resected primary melanoma thicker than 1.5 mm without clinically detectable node metastases
-
J.J. Grob, B. Dreno, and P. de la Salmonire Randomised trial of interferon alpha-2a as adjuvant therapy in resected primary melanoma thicker than 1.5 mm without clinically detectable node metastases Lancet 351 1998 1905 1910
-
(1998)
Lancet
, vol.351
, pp. 1905-1910
-
-
Grob, J.J.1
Dreno, B.2
De La Salmonire, P.3
-
23
-
-
7144264391
-
Adjuvant interferon alfa-2a treatment in resected primary stage II cutaneous melanoma: Austrian Malignant Melanoma Cooperative Group
-
H. Pehamberger, H.P. Soyer, and A. Steiner Adjuvant interferon alfa-2a treatment in resected primary stage II cutaneous melanoma Austrian Malignant Melanoma Cooperative Group J Clin Oncol 16 1998 1425 1429
-
(1998)
J Clin Oncol
, vol.16
, pp. 1425-1429
-
-
Pehamberger, H.1
Soyer, H.P.2
Steiner, A.3
-
24
-
-
0035805053
-
Adjuvant interferon alpha 2b in high risk melanomathe Scottish study
-
D.A. Cameron, M.C. Cornbleet, and R.M. Mackie Adjuvant interferon alpha 2b in high risk melanomathe Scottish study Br J Cancer 84 2001 1146 1149
-
(2001)
Br J Cancer
, vol.84
, pp. 1146-1149
-
-
Cameron, D.A.1
Cornbleet, M.C.2
MacKie, R.M.3
-
25
-
-
3242686449
-
Adjuvant interferon in high-risk melanoma: The AIM HIGH StudyUnited Kingdom Coordinating Committee on Cancer Research randomized study of adjuvant low-dose extended-duration interferon alfa-2a in high-risk resected malignant melanoma
-
B.W. Hancock, K. Wheatley, and S. Harris Adjuvant interferon in high-risk melanoma: the AIM HIGH StudyUnited Kingdom Coordinating Committee on Cancer Research randomized study of adjuvant low-dose extended-duration interferon alfa-2a in high-risk resected malignant melanoma J Clin Oncol 22 2004 53 61
-
(2004)
J Clin Oncol
, vol.22
, pp. 53-61
-
-
Hancock, B.W.1
Wheatley, K.2
Harris, S.3
-
26
-
-
0035883950
-
Effect of long-term adjuvant therapy with interferon alpha-2a in patients with regional node metastases from cutaneous melanoma: A randomised trial
-
N. Cascinelli, F. Belli, and R.M. MacKie Effect of long-term adjuvant therapy with interferon alpha-2a in patients with regional node metastases from cutaneous melanoma: a randomised trial Lancet 358 2001 866 869
-
(2001)
Lancet
, vol.358
, pp. 866-869
-
-
Cascinelli, N.1
Belli, F.2
MacKie, R.M.3
-
27
-
-
44849131339
-
Adjuvant low-dose interferon α2a with or without dacarbazine compared with surgery alone: A prospective-randomized phase III DeCOG trial in melanoma patients with regional lymph node metastasis
-
C. Garbe, P. Radny, and R. Linse Adjuvant low-dose interferon α2a with or without dacarbazine compared with surgery alone: a prospective- randomized phase III DeCOG trial in melanoma patients with regional lymph node metastasis Ann Oncol 19 2008 1195 1201
-
(2008)
Ann Oncol
, vol.19
, pp. 1195-1201
-
-
Garbe, C.1
Radny, P.2
Linse, R.3
-
28
-
-
1642554821
-
Final results of the EORTC 18871/DKG 80-1 randomised phase III trial: RIFN-alpha2b versus rIFN-gamma versus ISCADOR M versus observation after surgery in melanoma patients with either high-risk primary (thickness >3 mm) or regional lymph node metastasis
-
U.R. Kleeberg, S. Suciu, and E.B. Brcker Final results of the EORTC 18871/DKG 80-1 randomised phase III trial rIFN-alpha2b versus rIFN-gamma versus ISCADOR M versus observation after surgery in melanoma patients with either high-risk primary (thickness >3 mm) or regional lymph node metastasis Eur J Cancer 40 2004 390 402
-
(2004)
Eur J Cancer
, vol.40
, pp. 390-402
-
-
Kleeberg, U.R.1
Suciu, S.2
Brcker, E.B.3
-
29
-
-
0041409703
-
Does adjuvant interferon-alpha for high-risk melanoma provide a worthwhile benefit?: A meta-analysis of the randomised trials
-
K. Wheatley, N. Ives, and B. Hancock Does adjuvant interferon-alpha for high-risk melanoma provide a worthwhile benefit? A meta-analysis of the randomised trials Cancer Treat Rev 29 2003 241 252
-
(2003)
Cancer Treat Rev
, vol.29
, pp. 241-252
-
-
Wheatley, K.1
Ives, N.2
Hancock, B.3
-
30
-
-
35648931008
-
Interferon-α as adjuvant therapy for melanoma: An individual patient data meta-analysis of randomised trials
-
K. Wheatley, N. Ives, and A.M. Eggermont Interferon-α as adjuvant therapy for melanoma: an individual patient data meta-analysis of randomised trials [abstract 8526] J Clin Oncol 25 Suppl 2007
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Wheatley, K.1
Ives, N.2
Eggermont, A.M.3
-
31
-
-
46749103710
-
Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: Final results of EORTC 18991, a randomised phase III trial
-
A.M. Eggermont, S. Suciu, and M. Santinami Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial Lancet 372 2008 117 126
-
(2008)
Lancet
, vol.372
, pp. 117-126
-
-
Eggermont, A.M.1
Suciu, S.2
Santinami, M.3
-
32
-
-
72449177399
-
Ulceration of primary melanoma and responsiveness to adjuvant interferon therapy: Analysis of the adjuvant trials EORTC18952 and EORTC18991 in 2644 patients
-
A.M. Eggermont, S. Suciu, and A. Testori Ulceration of primary melanoma and responsiveness to adjuvant interferon therapy: analysis of the adjuvant trials EORTC18952 and EORTC18991 in 2644 patients [abstract 9007] J Clin Oncol 18 Suppl 2009
-
(2009)
J Clin Oncol
, vol.18
, Issue.SUPPL.
-
-
Eggermont, A.M.1
Suciu, S.2
Testori, A.3
-
33
-
-
61449090474
-
Phase I/II trial of tremelimumab in patients with metastatic melanoma
-
L.H. Camacho, S. Antonia, and J. Sosman Phase I/II trial of tremelimumab in patients with metastatic melanoma J Clin Oncol 27 2009 1075 1081
-
(2009)
J Clin Oncol
, vol.27
, pp. 1075-1081
-
-
Camacho, L.H.1
Antonia, S.2
Sosman, J.3
-
34
-
-
55949137090
-
Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma
-
A. Ribas, A. Hauschild, and R. Kefford Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma [abstract 9011] J Clin Oncol 26 Suppl 2008
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Ribas, A.1
Hauschild, A.2
Kefford, R.3
-
35
-
-
78449239072
-
Phase II evaluation of tremelimumab (Treme) combined with high-dose interferon alpha-2b (HDI) for metastatic melanoma
-
A.A. Tarhini, S.J. Moschos, and H. Tawbi Phase II evaluation of tremelimumab (Treme) combined with high-dose interferon alpha-2b (HDI) for metastatic melanoma [abstract 8524] J Clin Oncol 28 Suppl 2010
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Tarhini, A.A.1
Moschos, S.J.2
Tawbi, H.3
-
36
-
-
55949101240
-
Disease control and long-term survival in chemotherapy-naive patients with advanced melanoma treated with ipilimumab (MDX- 010) with or without dacarbazine
-
E.M. Hersh, J.S. Weber, and J.D. Powderly Disease control and long-term survival in chemotherapy-naive patients with advanced melanoma treated with ipilimumab (MDX- 010) with or without dacarbazine [abstract 9022] J Clin Oncol 26 Suppl 2008
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Hersh, E.M.1
Weber, J.S.2
Powderly, J.D.3
-
37
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
P. Attia, G.Q. Phan, and A.V. Maker Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4 J Clin Oncol 23 2005 6043 6053
-
(2005)
J Clin Oncol
, vol.23
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.V.3
-
38
-
-
36748999428
-
Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade
-
S.G. Downey, J.A. Klapper, and F.O. Smith Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade Clin Cancer Res 13 2007 6681 6688
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6681-6688
-
-
Downey, S.G.1
Klapper, J.A.2
Smith, F.O.3
-
39
-
-
33744792341
-
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
-
K.E. Beck, J.A. Blansfield, and K.Q. Tran Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4 J Clin Oncol 24 2006 2283 2289
-
(2006)
J Clin Oncol
, vol.24
, pp. 2283-2289
-
-
Beck, K.E.1
Blansfield, J.A.2
Tran, K.Q.3
-
40
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study
-
J.D. Wolchok, B. Neyns, and G. Linette Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study Lancet Oncol 11 2010 155 164
-
(2010)
Lancet Oncol
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
-
41
-
-
78449243659
-
Activity of ipilimumab at 10mg/kg in patients with advanced melanoma is independent of baseline prognostic factors
-
D. Schadendorf, J. Wolchok, and B. Neyns Activity of ipilimumab at 10mg/kg in patients with advanced melanoma is independent of baseline prognostic factors Eur J Cancer Suppl 7 2009 579
-
(2009)
Eur J Cancer Suppl
, vol.7
, pp. 579
-
-
Schadendorf, D.1
Wolchok, J.2
Neyns, B.3
-
42
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
F.S. Hodi, S.J. O'Day, and D.F. McDermott Improved survival with ipilimumab in patients with metastatic melanoma N Engl J Med 363 2010 711 723
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
|