Insulin-like growth factor I plays a role in gastric wound healing: Evidence using a zinc derivative, polaprezinc, and an in vitro rabbit wound repair model

Alimentary Pharmacology and Therapeutics

Volumn 12, Issue 11, 1998, Pages 1131-1138

  Watanabe, S ^a   Wang, X E ^a   Hirose, M ^a   Kivilioto, T ^a   Osada, T ^a   Miwa, H ^a   Oide, H ^a   Kitamura, T ^a   Yoneta, T ^b   Seto, K ^b   Sato, N ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b ZERIA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BROXURIDINE; MESSENGER RNA; POLAPREZINC; SCATTER FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG MECHANISM; FIBROBLAST; HUMAN; HUMAN CELL; MALE; MESENCHYME; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM; STOMACH ULCER; WOUND HEALING;

ANIMALS; BLOTTING, SOUTHERN; CARNOSINE; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; FIBROBLASTS; GASTRIC MUCOSA; GENE EXPRESSION; GROWTH SUBSTANCES; INSULIN-LIKE GROWTH FACTOR I; MALE; MESODERM; ORGANOMETALLIC COMPOUNDS; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; WOUND HEALING;

EID: 7844227321     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.1998.00408.x     Document Type: Article

References (39)

1. Vallee BL, Falchuk KH. The biochemical basis of zinc physiology. Physiol Rev 1993; 73: 79-118.
2. Vallee BL, Falchuk KH. Zinc and gene expression. Philos Trans R Soc London B, Biol Sci 1981; 294: 185-97.
3. Shin YA, Eichhorn GL. Interactions of metal ions with polynucleotides and related compounds. XI. The reversible unwinding and rewinding of deoxyribonucleic acid by zinc (II) ions through temperature manipulation. Biochemistry 1968; 7: 1026-32.
4. Follis RH, Day HG, McCollum EV. Histologic studies of the tissues of rats fed a diet extremely low in zinc. J Nutr 1941; 22: 223-37.
5. Whitham SE, Murphy P, Angel HJ, et al. Comparison of human stromelysis and collagenase by cloning and sequence analysis. J Biochem 1986; 240: 913-16.
6. Van Wart HE, Birkedal-Hansen. The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire metalloproteinase gene family. Proc Natl Acad Sci USA 1990; 87: 5578-5582.
7. Cho Ch, Ogle CW, Dai S. Effects of zinc chloride on gastric secretion and ulcer formation in pylorus-occluded rats. Eur J Pharmacol 1976; 38: 337-41.
8. Fraser PM, Doll R, Langman MSS, Mieiewicz JJ, Shawdon HH. Clinical trial of a new carbenoxolone analogue (BX24), zinc sulfate, and vitamin A in the treatment of gastric ulcer. Gut 1972; 13: 459-63.
9. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975; 2: 793-6.
10. Navarro C, Escolar G, Bravo ML, Jimenez E, Bulbena O. Effect of zinc acexamate and ranitidine on chronic gastric lesions in the rat. Digestion 1990; 45: 121-9.
11. Arakawa T, Satoh H, Nakamura H, et al. Effects of zinc L-calnosine on gastric mucosal and cell damage caused by ethanol in rats: correlation with endogenous prostaglandin E2. Dig Dis Sci 1990; 35: 559-66.
12. Ito M, Tanaka T, Suzuki Y. Effect of N-(3-aminopropionyl)-L-histinato zinc (Z-103) on healing and hydrocortisone-induced relapse of acetic acid ulcers in rats with limited food intake-time. Jpn J Pharmacol 1990; 52: 513-21.
13. Yamakawa A. Effect of 1-carnosine (N-2-M) on experimental gastric ulcer. J Showa Med Assoc 1975; 35: 113-26.
14. Humbel R. Insulin-like growth factors I and II. Eur J Biochem 1990; 190: 445-62.
15. Lund PK, Moats-Staats BM, Hynes MA, et al. Somatomedin/insulin-like growth factor-I and insulin-like growth factor-II in rat fetal and adult tissues. J Biol Chem 1986; 31: 14539-44.
16. Baker J, Liu JP, Robertson EJ, Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 1993; 75: 73-82.
17. Chen MC, Lee AT, Soll AH. Mitogenic response of canine fundic epithelial cells in short-term culture of transforming growth factor α and insulin like growth factor I. J Clin Invest 1991; 87: 1716-23.
18. Steenfos HH, Jansson JO. Gene expression of insulin-like growth factor-I and IGF-I receptor during wound healing in rats. Eur J Surg 1992; 158: 327-31.
19. Watanabe S, Hirose M, Yasuda T, Sato N. Role of actin and calmodulin in migration and proliferation of rabbit gastric mucosal cells in culture. J Gastroenterol Hepatol 1994; 9: 325-33.
20. Watanabe S, Wang XE, Hirose M, Sato N. Effect of myosin light chain kinase inhibitor wortmannin on the wound repair of cultured gastric mucosal cells. Biochem Biophys Res Commun 1994; 199: 799-806.
21. Mikami H, Watanabe S, Hirose M, Sato N. Role of extracellular matrix in wound repair by cultured gastric mucosal cells. Biochem Biophys Res Commun 1994; 202: 285-92.
22. Watanabe S, Wang XE, Hirose M, et al. Platelet-derived growth factor accelerates gastric epithelial restoration in a rabbit cultured cell model. Gastroenterology 1996; 110: 775-9.
23. Chomczynski P, Sacchi N. Single-step methods of isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-9.
24. Faber A, Chung C, Soll C, et al. Failure of senescent human fibroblasts to express insulin-like growth factor-I gene. J Biol Chem 1993; 268: 17883-8.
25. Fukamachi H, Ichinose M, Tsukada S, et al. Hepatocyte growth factor region specifically stimulates gastrointestinal epithelial growth in primary culture. Biochem Biophys Res Commun 1994; 205: 1445-51.
26. Van Zoelen EJJ, Delacy B, Burg VD, Huylebroeck B. Growth Factor: a Practical Approach. In: McKay IA, Leigh IM, eds. Oxford: Oxford University Press. 1993: 11-30 (in Japanese). Translated by T Nakamura, Medical Science International Tokyo, 1995.
27. Maehiro K, Watanabe S, Hirose M, Sato N. Effects of epidermal growth factor and insulin on the proliferation and migration of primary gastric epithelial cells in culture. J Gastroenterol 1997; 32: 573-8.
28. Kobayashi O, Watanabe S, Hirose M, Sato N. Effects of transforming growth factors on the wound repair of cultured gastric rabbit gastric mucosal cells. J Gastroenterol Hepatol 1996; 11: 129-36.
29. Watanabe S, Hirose M, Wang XE, et al. Hepatocyte growth factor accelerates the wound repair of cultured gastric mucosal cells. Biochem Biophys Res Commun 1994; 199: 1453-60.
30. Watanabe S, Wang XE, Hirose M, et al. Basic Fibroblast growth factor accelerates gastric mucosal repair in vitro by promoting mesenchymal cell migration and proliferation. J Gastroenterol Hepatol 1996; 11: 129-36.
31. Laburthe M, Rouyer-Fessard C, Gammeltoft S. Receptors for insulin-like growth factors I and II in rat gastrointestinal epithelium. Am J Physiol 1988; 254: G457-62.
32. Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Kondo M. The antioxidant properties of a novel zinc-carnosine chelate compound. N-(3-aminopropionyl)-L-histidinato zinc. Biochim Biophys Acta 1991; 1115: 15-22.
33. Yoshikawa T, Naito Y, Tanigawa T. et al. Effect of zinc-carnosine chelate compound (Z-103), a novel antioxidant, on acute gastric mucosal injury induced by ischemia-reperfusion in rat. Free Rad Res Commun 1991; 14: 289-96.
34. Fraser RM, Doll R, Langman MJS, Misiewicz JJ, Shawdon HH. Clinical trial of a new carbonoxolone analogue (BX24), zinc sulphate and vitamin A in the treatment of gastric ulcer. Gut 1972; 13: 459-61.
35. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1985; 2: 793-5.
36. Alcala-Santaella R, Castellanos D, Velo JL, Gonzalez-Lara V. Zinc acexamate in treatment of duodenal ulcer. Lancet 1985; 2: 157.
37. Coerper S, von Kiparski S, Ranke MB, Becker HD, Koveker G. Healing of experimental gastric full thickness ulcers is stimulated by local application of IGF-1. Gastroenterology 1997; 112: A92(Abstract).
38. Oureshi FG, Tchorzewski MT, Duncan MD, Harmon JW. IGF-1 promotes healing of experimental acid-pepsin induced erosive esophagitis. Gastroenterology 1997; 112: A263(Abstract).
39. Dignass AU, Podolsky DK. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor γ. Gastroenterology 1993; 105: 1323-32.