Cost-effectiveness of adding decolonization to a surveillance strategy of screening and isolation for methicillin-resistant Staphylococcus aureus carriers

Clinical Microbiology and Infection

Volumn 16, Issue 12, 2010, Pages 1740-1746

  Nelson, R E ^a   Samore, M H ^a   Smith, K J ^b   Harbarth, S ^c   Rubin, M A ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Active surveillance; Chlorhexidine; Cost effectiveness analysis; Decolonization; MRSA; Mupirocin

Indexed keywords

CHLORHEXIDINE; PSEUDOMONIC ACID;

ACTIVE SURVEILLANCE; ANALYTIC METHOD; ARTICLE; BACTERIUM ISOLATION; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DECISION ANALYTICAL MODEL; HUMAN; INFECTION RISK; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MONITORING; MONTE CARLO METHOD; NONHUMAN; ONE WAY SENSITIVITY ANALYSIS; PRIORITY JOURNAL; SCREENING; TWO WAY SENSITIVITY ANALYSIS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 78349299754     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2010.03324.x     Document Type: Article

References (30)

1. Eber MR, Laxminarayan R, Perencevich EN, Malani A. Clinical and economic outcomes attributable to health care-associated sepsis and pneumonia. Arch Intern Med 2010; 170: 347-353.
2. European Centre for Disease Prevention and Control. Annual epidemiological report on communicable disease in Europe. Stockholm: European Centre for Disease Prevention and Control, 2008.
3. Huang SS, Platt R. Risk of methicillin-resistant Staphylococcus aureus infection after previous infection or colonization. Clin Infect Dis 2003; 36: 281-285.
4. Harbarth S, Fankhauser C, Schrenzel J et al. Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. JAMA 2008; 299: 1149-1157.
5. Muder RR, Cunningham C, McCray E et al. Implementation of an industrial systems-engineering approach to reduce the incidence of methicillin-resistant Staphylococcus aureus infection. Infect Control Hosp Epidemiol 2008; 29: 702-708.
6. Ammerlaan HS, Kluytmans JA, Wertheim HF, Nouwen JL, Bonten MJ. Eradication of methicillin-resistant Staphylococcus aureus carriage: a systematic review. Clin Infect Dis 2009; 48: 922-930.
7. Murthy A, De Angelis G, Pittet D, Schrenzel J, Uckay I, Harbarth S. Cost-effectiveness of universal MRSA screening on admission to surgery. Clin Microbiol Infect 2010; 16: 1747-1753.
8. Noskin GA, Rubin RJ, Schentag JJ et al. Budget impact analysis of rapid screening for Staphylococcus aureus colonization among patients undergoing elective surgery in US hospitals. Infect Control Hosp Epidemiol 2008; 29: 16-24.
9. Ritchie K, Bradbury I, Craig J et al. The clinical and cost effectiveness of screening for methicillin-resistant Staphylococcus aureus (MRSA). Health Technology Assessment Report 9. Glasgow: NHS Quality Improvement Scotland, 2007.
10. Young LS, Winston LG. Preoperative use of mupirocin for the prevention of healthcare-associated Staphylococcus aureus infections: a cost-effectiveness analysis. Infect Control Hosp Epidemiol 2006; 27: 1304-1312.
11. Bloom BS, Fendrick AM, Chernew ME, Patel P. Clinical and economic effects of mupirocin calcium on preventing Staphylococcus aureus infection in hemodialysis patients: a decision analysis. Am J Kidney Dis 1996; 27: 687-694.
12. Baker SE, Brecher SM, Robillard E, Strymish J, Lawler E, Gupta K. Extranasal methicillin-resistant Staphylococcus aureus colonization at admission to an acute care Veterans Affairs hospital. Infect Control Hosp Epidemiol 2010; 31: 42-46.
13. Cook A, Berne J, Norwood S. The incidence and complications of methicillin-resistant Staphylococcus aureus in a community Level I trauma center. J Trauma 2009; 67: 102-107.
14. Croft CA, Mejia VA, Barker DE et al. Methicillin-resistant Staphylococcus aureus in a trauma population: does colonization predict infection? Am Surg 2009; 75: 458-461. Discussion 61-62.
15. Marshall C, Spelman D, Harrington G, McBryde E. Daily hazard of acquisition of methicillin-resistant Staphylococcus aureus infection in the intensive care unit. Infect Control Hosp Epidemiol 2009; 30: 125-129.
16. Ohara S, Malhotra-Kumar S, Haccuria K, Van Heirstraeten L, Ieven M, Goossens H. Novel rapid culture-based detection method for methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2008; 46: 3181. Author reply 381-382.
17. Datta R, Huang SS. Risk of infection and death due to methicillin-resistant Staphylococcus aureus in long-term carriers. Clin Infect Dis 2008; 47: 176-181.
18. Kluytmans J, Harbarth S. Methicillin-resistant Staphylococcus aureus decolonization: 'yes, we can', but will it help? Infect Control Hosp Epidemiol 2009; 30: 633-635.
19. Hudgens MG, Halloran ME. Toward causal inference with interference. J Am Stat Assoc 2008; 103: 832-842.
20. Harbarth S, Masuet-Aumatell C, Schrenzel J et al. Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study. Crit Care 2006; 10: R25.
21. Mangini E, Segal-Maurer S, Burns J et al. Impact of contact and droplet precautions on the incidence of hospital-acquired methicillin-resistant Staphylococcus aureus infection. Infect Control Hosp Epidemiol 2007; 28: 1261-1266.
22. Anderson DJ, Kaye KS, Chen LF et al. Clinical and financial outcomes due to methicillin resistant Staphylococcus aureus surgical site infection: a multi-center matched outcomes study. PLoS ONE 2009; 4: e8305.
23. Edmond MB, Ober JF, Bearman G. Active surveillance cultures are not required to control MRSA infections in the critical care setting. Am J Infect Control 2008; 36: 461-463.
24. Evans HL, Dellit TH, Chan J, Nathens AB, Maier RV, Cuschieri J. Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients. Arch Surg 2010; 145: 240-246.
25. Puzniak LA, Gillespie KN, Leet T, Kollef M, Mundy LM. A cost-benefit analysis of gown use in controlling vancomycin-resistant Enterococcus transmission: is it worth the price? Infect Control Hosp Epidemiol 2004; 25: 418-424.
26. DeFrances CJ, Hall MJ, Podgomik MN. 2003 National hospital discharge survey. Advance data from vital and health statistics; no. 359. Hyattsville, MD: National Center for Health Statistics, 2005.
27. Cummings KL, Anderson DJ, Kaye KS. Hand hygiene noncompliance and the cost of hospital-acquired methicillin-resistant Staphylococcus aureus infection. Infect Control Hosp Epidemiol 2010; 31: 357-364.
28. Lee BY, Tsui BY, Bailey RR et al. Should vascular surgery patients be screened preoperatively for methicillin-resistant Staphylococcus aureus? Infect Control Hosp Epidemiol 2009; 30: 1158-1165.
29. Harbarth S, Liassine N, Dharan S, Herrault P, Auckenthaler R, Pittet D. Risk factors for persistent carriage of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2000; 31: 1380-1385.
30. Paule SM, Pasquariello AC, Thomson RB Jr, Kaul KL, Peterson LR. Real-time PCR can rapidly detect methicillin-susceptible and methicillin-resistant Staphylococcus aureus directly from positive blood culture bottles. Am J Clin Pathol 2005; 124: 404-407.