Association between bone turnover rate and bone microarchitecture in men: The STRAMBO study

Journal of Bone and Mineral Research

Volumn 25, Issue 11, 2010, Pages 2313-2323

  Chaitou, Ali ^a   Boutroy, Stephanie ^a   Vilayphiou, Nicolas ^a   Munoz, Françoise ^a   Delmas, Pierre D ^a   Chapurlat, Roland ^a   Szulc, Pawel ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

bone turnover markers; cortical bone; men; osteoporosis; trabecular bone

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; BIOLOGICAL MARKER; DEOXYPYRIDINOLINE; OSTEOCALCIN; PROCOLLAGEN; PROCOLLAGEN TYPE 1 AMINO TERMINAL PROPEPTIDE; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; BONE DENSITY; BONE STRUCTURE; BONE TURNOVER; CORTICAL BONE; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; MALE; OSSIFICATION; OSTEOLYSIS; RADIUS; THICKNESS; TIBIA; TRABECULAR BONE; URINARY EXCRETION;

ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; AGING; BIOLOGICAL MARKERS; BONE AND BONES; BONE REMODELING; BONE RESORPTION; COHORT STUDIES; HUMANS; MALE; MIDDLE AGED; OSTEOGENESIS; RADIUS; TIBIA; YOUNG ADULT;

EID: 78349298254     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.124     Document Type: Article

References (28)

1. Cooper C, Campion G, Melton LJ III., Hip fractures in the elderly: a worldwide projection. Osteoporosis Int. 1992; 2: 285 -289.
2. Siris ES, Miller PD, Barrett-Connor E, et al. Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: result from the National Osteoporosis Risk Assessment. JAMA. 2001; 286: 2815 -2822.
3. Schuit SC, van der Klift M, Weel AE, et al. Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam study. Bone. 2006; 34: 195 -202.
4. Sornay-Rendu E, Munoz F, Garnero P, Duboeuf F, Delmas PD,. Identification of osteopenic women at high risk of fracture: the OFELY study. J Bone Miner Res. 2005; 20: 1813 -1819.
5. Szulc P, Munoz F, Duboeuf F, Marchand F, Delmas PD,. Bone mineral density predicts osteoporotic fractures in elderly men: the MINOS study. Osteoporos Int. 2005; 16: 1184 -1192.
6. Black DM, Bouxsein ML, Marshall LM, et al. Osteoporotic Fractures in Men (MrOS) Research Group. Proximal femoral structure and the prediction of hip fracture in men: A large prospective study using QCT. J Bone Miner Res. 2008; 23: 1326 -1333.
7. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy 2001 Osteoporosis prevention, diagnosis, and therapy. JAMA. 285: 785 -795.
8. Majumdar S, Genant HK, Grampp S, et al. Correlation of trabecular bone structure with age, bone mineral density, and osteoporotic status: in vivo studies in the distal radius using high resolution magnetic resonance imaging. J Bone Miner Res. 1997; 12: 111 -118.
9. Sornay-Rendu E, Boutroy S, Munoz F, Delmas PD,. Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study. J Bone Miner Res. 2007; 22: 425 -433.
10. Sornay-Rendu E, Cabrera-Bravo JL, Boutroy S, Munoz F, Delmas PD,. Severity of vertebral fractures is associated with alterations of cortical architecture in postmenopausal women. J Bone Miner Res. 2009; 24: 737 -743.
11. Boutroy S, Vilayphiou N, Chapurlat R, Szulc P,. -Age-related changes in bone microarchitecture in men -the STRAMBO study. (manuscript in preparation).
12. Szulc P, Kaufman JM, Delmas PD,. Biochemical assessment of bone turnover and bone fragility in men. Osteoporos Int. 2007; 18: 1451 -1461.
13. Szulc P, Garnero P, Munoz F, Marchand F, Delmas PD,. Cross-sectional evaluation of bone metabolism in men. J Bone Miner Res. 2001; 16: 1642 -1650.
14. Khosla S, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Klee GG, Riggs BL,. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. 1998; 83: 2266 -2274.
15. Wishart JM, Need AG, Horowitz M, Morris HA, Nordin BE,. Effect of age on bone density and bone turnover in men. Clin Endocrinol. 1995; 42: 141 -146.
16. Fatayerji D, Eastell R,. Age-related changes in bone turnover in men. J Bone Miner Res. 1999; 14: 1203 -1210.
17. Melton LJ, Khosla S, Atkinson E, O'fallon WM, Riggs BL,. Relationship of bone turnover to bone density and fractures. J Bone Miner Res. 1997; 12: 1083 -1091.
18. Khosla S, Melton LJ 3rd, Achenbach SJ, Oberg AL, Riggs BL,. Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men. J Clin Endocrinol Metab. 2006; 91: 885 -891.
19. Riggs BL, Melton LJ, Robb RA, et al. A Population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res. 2008; 23: 205 -214.
20. Boutroy S, Bouxsein ML, Munoz F, Delmas PD,. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab. 2005; 90: 6508 -6515.
21. Qvist P, Christgau S, Pedersen BJ, Schlemmer A, Christiansen C,. Circadian variation in the serum concentration of C-terminal telopeptide of type I collagen (serum CTx): Effects of gender, age, menopausal status, posture, daylight, serum cortisol, and fasting. Bone. 2002; 31: 57 -61.
22. Bollen AM, Martin MD, Leroux BG, Eyre DR,. Circadian variation in urinary excretion of bone collagen cross-links. J Bone Miner Res. 1995; 10: 1885 -1890.
23. Zebaze R, Ghasem A, Bohte A, et al. The neglected role of intracortical remodelling in age-related bone loss. J Bone Miner Res. 2008; 23 (Suppl 1): S29.
24. Szulc P, Montella A, Delmas PD,. High bone turnover is associated with accelerated bone loss but not with increased fracture risk in men aged 50 and over -the prospective MINOS study. Ann Rheum Dis. 2008; 67: 1249 -1255.
25. Goemaere SJA, Zmierczak H, Van Pottelbergh I, Demuynck R, Myny H, Kaufman JM,. Association of bone turnover with longitudinally assessed bone loss in community-dwelling elderly men. J Bone Miner Res. 2001; 16 (Suppl 1): S395.
26. Riggs BL, Melton LJ 3rd, Robb RA, et al. Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res. 2004; 19: 1945 -1954.
27. Aaron JE, Makins NB, Sagreiya K,. The microanatomy of trabecular bone loss in normal aging men and women. Clin Orthop Relat Res. 1987; 215: 260 -271.
28. Bauer DC, Garnero P, Harrison SL, et al. Biochemical markers of bone turnover, hip bone loss and non-spine fracture in men: a prospective study. J Bone Miner Res. 2009; 24: 2032 -2038.