Glucosamine and osteoarthritis: Conclusions not supported by methods and results

BMJ (Online)

Volumn 341, Issue 7781, 2010, Pages 1110-

  Giacovelli, Giampaolo ^a,b   Rovati, Lucio C ^b  

^a Department of Biostatistics ^*  (United States)

^b Rotta Research Laboratorium   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSAMINE; GLUCOSAMINE SULFATE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL;

BAYES THEOREM; CLINICAL RESEARCH; EFFECT SIZE; LETTER; METHODOLOGY; OSTEOARTHRITIS; PRESCRIPTION; PRIORITY JOURNAL; STUDY DESIGN;

EID: 78349280816     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.c6338     Document Type: Letter

References (6)

1. Wandel S, Jüni P, Tendal B, Nüesch E, Villiger PM, Welton NJ, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010;341:c4675. (16 September.)
2. Zhang W, Nuki G, Moskowitz RW, Abramson S, Altman RD, Arden NK, et al. OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage 2010;18:476-99.
3. Towheed TE, Maxwell L, Anastassiades TP, Shea B, Houpt J, Robinson V, et al. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev 2009;2:CD002946.
4. Reginster JY. The efficacy of glucosamine sulfate in osteoarthritis: financial and nonfinancial conflict of interest. Arthritis Rheum 2007;56:2105-10.
5. Pocock SJ. Safety of drug-eluting stents: demystifying network meta-analysis. Lancet 2007;370:2099-100.
6. Reginster JY, Altman RD, Hochberg MC. Prescription glucosamine sulphate is effective in knee osteoarthritis. bmj.com 2010. www.bmj.com/content/341/bmj. c4675.full/reply#bmj-el-242366.