Isomerization-induced asymmetric coordination chemistry: From auxiliary control to asymmetric catalysis

Angewandte Chemie - International Edition

Volumn 49, Issue 43, 2010, Pages 7955-7957

  Gong, Lei ^a   Lin, Zhijie ^a   Harms, Klaus ^a   Meggers, Eric ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Asymmetric catalysis; Auxiliary control; Chirality; Coordination chemistry; Ruthenium

Indexed keywords

ASYMMETRIC CATALYSIS; AUXILIARY CONTROL; BIPYRIDINE LIGANDS; COORDINATION CHEMISTRY; ELECTRON-RICH; METHOXY; OCTAHEDRAL COORDINATION; RUTHENIUM COMPLEXES; TRANS-CIS ISOMERIZATION;

CATALYSIS; CHIRALITY; ENANTIOMERS; ISOMERIZATION; PHENOLS; RUTHENIUM; RUTHENIUM COMPOUNDS; SPHERES; STEREOCHEMISTRY;

COORDINATION REACTIONS;

EID: 78349273626     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201003139     Document Type: Article

References (25)

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23. Optimized reaction conditions for the asymmetric catalysis with chiral sulfoxides: 300 m M 1, 0.2 equiv (S)- SO or (S)- SO′, 1.0 equiv bpy, 6.0 equiv TFA, ethylene glycol, 95 C in a sealed brown-glass vial under air, 48 h; thereafter addition of 10 equiv bpy and another 2 h at 95 C to replace the ruthenium-bound catalyst. See the Supporting Information for more details.
24. The chiral sulfoxides are configurationally stable under the acidic reaction conditions.
25. The ruthenium complex intermediates and products were tested to be configurationally stable and soluble under the applied reactions conditions, which excludes mechanistic explanations for the observed enantiomeric excess involving chiral ion-pairing interactions or solubility differences of the intermediate ruthenium diastereomers.