메뉴 건너뛰기




Volumn 191, Issue 4, 2010, Pages 783-784

PIASy-dependent SUMOylation regulates DNA topoisomerase IIα activity

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE TYPE 2 ALPHA; LYSINE; UNCLASSIFIED DRUG;

EID: 78349263872     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.201004033     Document Type: Article
Times cited : (58)

References (45)
  • 1
    • 42049102803 scopus 로고    scopus 로고
    • Conjugation of human topoisomerase 2alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: Cell cycle stage and chromosome domain specificity
    • DOI 10.1158/0008-5472.CAN-07-2092
    • Agostinho, M., V. Santos, F. Ferreira, R. Costa, J. Cardoso, I. Pinheiro, J. Rino, E. Jaffray, R.T. Hay, and J. Ferreira. 2008. Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity. Cancer Res. 68:2409-2418. doi:10.1158/0008-5472.CAN-07-2092 (Pubitemid 351521816)
    • (2008) Cancer Research , vol.68 , Issue.7 , pp. 2409-2418
    • Agostinho, M.1    Santos, V.2    Ferreira, F.3    Costa, R.4    Cardoso, J.5    Pinheiro, I.6    Rino, J.7    Jaffray, E.8    Hay, R.T.9    Ferreira, J.10
  • 2
    • 0036021789 scopus 로고    scopus 로고
    • Active, but not inactive, human centromeres display topoisomerase II activity in vivo
    • doi:10.1023/A:1016571825025
    • Andersen, C.L., A. Wandall, E. Kjeldsen, C. Mielke, and J. Koch. 2002. Active, but not inactive, human centromeres display topoisomerase II activity in vivo. Chromosome Res. 10:305-312. doi:10.1023/A:1016571825025
    • (2002) Chromosome Res. , vol.10 , pp. 305-312
    • Andersen, C.L.1    Wandall, A.2    Kjeldsen, E.3    Mielke, C.4    Koch, J.5
  • 3
    • 0038686567 scopus 로고    scopus 로고
    • The Ran GTPase regulates kinetochore function
    • doi:10.1016/S1534-5807(03)00194-1
    • Arnaoutov, A., and M. Dasso. 2003. The Ran GTPase regulates kinetochore function. Dev. Cell. 5:99-111. doi:10.1016/S1534-5807(03)00194-1
    • (2003) Dev. Cell. , vol.5 , pp. 99-111
    • Arnaoutov, A.1    Dasso, M.2
  • 4
    • 73949099075 scopus 로고    scopus 로고
    • Analysis of SUMOylation of topoisomerase IIalpha with Xenopus egg extracts
    • doi:10.1007/ 978-1-60761-340-4-17
    • Azuma, Y. 2009. Analysis of SUMOylation of topoisomerase IIalpha with Xenopus egg extracts. Methods Mol. Biol. 582:221-231. doi:10.1007/ 978-1-60761-340-4-17
    • (2009) Methods Mol. Biol. , vol.582 , pp. 221-231
    • Azuma, Y.1
  • 6
    • 0242509262 scopus 로고    scopus 로고
    • SUMO-2/3 regulates topoisomerase II in mitosis
    • doi:10.1083/jcb.200304088
    • Azuma, Y., A. Arnaoutov, and M. Dasso. 2003. SUMO-2/3 regulates topoisomerase II in mitosis. J. Cell Biol. 163:477-487. doi:10.1083/jcb. 200304088
    • (2003) J. Cell Biol. , vol.163 , pp. 477-487
    • Azuma, Y.1    Arnaoutov, A.2    Dasso, M.3
  • 7
    • 21844437072 scopus 로고    scopus 로고
    • PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes
    • doi:10.1038/sj.emboj.7600700
    • Azuma, Y., A. Arnaoutov, T. Anan, and M. Dasso. 2005. PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes. EMBO J. 24:2172-2182. doi:10.1038/sj.emboj.7600700
    • (2005) EMBO J. , vol.24 , pp. 2172-2182
    • Azuma, Y.1    Arnaoutov, A.2    Anan, T.3    Dasso, M.4
  • 8
    • 0036291014 scopus 로고    scopus 로고
    • The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II
    • doi:10.1016/S1097-2765(02)00543-9
    • Bachant, J., A. Alcasabas, Y. Blat, N. Kleckner, and S.J. Elledge. 2002. The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol. Cell. 9:1169-1182. doi:10.1016/S1097-2765(02)00543-9
    • (2002) Mol. Cell. , vol.9 , pp. 1169-1182
    • Bachant, J.1    Alcasabas, A.2    Blat, Y.3    Kleckner, N.4    Elledge, S.J.5
  • 9
    • 22144473328 scopus 로고    scopus 로고
    • Etoposide, topoisomerase II and cancer
    • doi:10.2174/ 1568011054222364
    • Baldwin, E.L., and N. Osheroff. 2005. Etoposide, topoisomerase II and cancer. Curr Med Chem Anticancer Agents. 5:363-372. doi:10.2174/ 1568011054222364
    • (2005) Curr Med Chem Anticancer Agents , vol.5 , pp. 363-372
    • Baldwin, E.L.1    Osheroff, N.2
  • 10
    • 0030045003 scopus 로고    scopus 로고
    • Structure and mechanism of DNA topoisomerase II
    • doi: 10.1038/379225a0
    • Berger, J.M., S.J. Gamblin, S.C. Harrison, and J.C. Wang. 1996. Structure and mechanism of DNA topoisomerase II. Nature. 379:225-232. doi: 10.1038/379225a0
    • (1996) Nature , vol.379 , pp. 225-232
    • Berger, J.M.1    Gamblin, S.J.2    Harrison, S.C.3    Wang, J.C.4
  • 11
    • 0036177128 scopus 로고    scopus 로고
    • Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
    • doi:10.1016/S0092-8674(02)00630-X
    • Bernier-Villamor, V., D.A. Sampson, M.J. Matunis, and C.D. Lima. 2002. Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell. 108:345-356. doi:10.1016/S0092-8674(02)00630-X
    • (2002) Cell. , vol.108 , pp. 345-356
    • Bernier-Villamor, V.1    Sampson, D.A.2    Matunis, M.J.3    Lima, C.D.4
  • 12
    • 0034754698 scopus 로고    scopus 로고
    • Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces Cerevisiae
    • Biggins, S., N. Bhalla, A. Chang, D.L. Smith, and A.W. Murray. 2001. Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics. 159:453-470.
    • (2001) Genetics , vol.159 , pp. 453-470
    • Biggins, S.1    Bhalla, N.2    Chang, A.3    Smith, D.L.4    Murray, A.W.5
  • 13
    • 0348013023 scopus 로고    scopus 로고
    • RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate
    • doi:10.1242/jcs.00797
    • Chang, C.J., S. Goulding, W.C. Earnshaw, and M. Carmena. 2003. RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate. J. Cell Sci. 116:4715-4726. doi:10.1242/jcs.00797
    • (2003) J. Cell Sci. , vol.116 , pp. 4715-4726
    • Chang, C.J.1    Goulding, S.2    Earnshaw, W.C.3    Carmena, M.4
  • 14
    • 40749131181 scopus 로고    scopus 로고
    • Emerging roles of the SUMO pathway in mitosis
    • doi:10.1186/1747-1028-3-5
    • Dasso, M. 2008. Emerging roles of the SUMO pathway in mitosis. Cell Div. 3:5. doi:10.1186/1747-1028-3-5
    • (2008) Cell Div. , vol.3 , pp. 5
    • Dasso, M.1
  • 15
  • 17
    • 48049100157 scopus 로고    scopus 로고
    • Chromosome cohesion - Rings, knots, orcs and fellowship
    • doi:10.1242/jcs.029132
    • Díaz-Martínez, L.A., J.F. Giménez-Abián, and D.J. Clarke. 2008. Chromosome cohesion - rings, knots, orcs and fellowship. J. Cell Sci. 121:2107-2114. doi:10.1242/jcs.029132
    • (2008) J. Cell Sci. , vol.121 , pp. 2107-2114
    • Díaz-Martínez, L.A.1    Giménez-Abián, J.F.2    Clarke, D.J.3
  • 18
    • 37549023863 scopus 로고    scopus 로고
    • Structural basis for gate-DNA recognition and bending by type IIA topoisomerases
    • doi:10.1038/nature06396
    • Dong, K.C., and J.M. Berger. 2007. Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature. 450:1201-1205. doi:10.1038/nature06396
    • (2007) Nature , vol.450 , pp. 1201-1205
    • Dong, K.C.1    Berger, J.M.2
  • 19
    • 36548998840 scopus 로고    scopus 로고
    • Concepts in sumoylation: A decade on
    • doi:10.1038/nrm2293
    • Geiss-Friedlander, R., and F. Melchior. 2007. Concepts in sumoylation: a decade on. Nat. Rev. Mol. Cell Biol. 8:947-956. doi:10.1038/nrm2293
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 947-956
    • Geiss-Friedlander, R.1    Melchior, F.2
  • 20
    • 0028329736 scopus 로고
    • Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane)
    • Gorbsky, G.J. 1994. Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane). Cancer Res. 54:1042-1048.
    • (1994) Cancer Res. , vol.54 , pp. 1042-1048
    • Gorbsky, G.J.1
  • 21
    • 0034993496 scopus 로고    scopus 로고
    • The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family
    • doi:10 .1101/gad.877901
    • Hari, K.L., K.R. Cook, and G.H. Karpen. 2001. The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family. Genes Dev. 15:1334-1348. doi:10 .1101/gad.877901
    • (2001) Genes Dev. , vol.15 , pp. 1334-1348
    • Hari, K.L.1    Cook, K.R.2    Karpen, G.H.3
  • 23
    • 0027965213 scopus 로고
    • Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events
    • doi:10.1083/jcb.126.6.1341
    • Ishida, R., M. Sato, T. Narita, K.R. Utsumi, T. Nishimoto, T. Morita, H. Nagata, and T. Andoh. 1994. Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events. J. Cell Biol. 126:1341-1351. doi:10.1083/jcb.126.6.1341
    • (1994) J. Cell Biol. , vol.126 , pp. 1341-1351
    • Ishida, R.1    Sato, M.2    Narita, T.3    Utsumi, K.R.4    Nishimoto, T.5    Morita, T.6    Nagata, H.7    Andoh, T.8
  • 25
    • 3943099375 scopus 로고    scopus 로고
    • Protein modification by SUMO
    • doi:10.1146/annurev.biochem.73.011303.074118
    • Johnson, E.S. 2004. Protein modification by SUMO. Annu. Rev. Biochem. 73:355-382. doi:10.1146/annurev.biochem.73.011303.074118
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 355-382
    • Johnson, E.S.1
  • 26
    • 0037128207 scopus 로고    scopus 로고
    • SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles
    • doi:10.1083/jcb.200110109
    • Joseph, J., S.H. Tan, T.S. Karpova, J.G. McNally, and M. Dasso. 2002. SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J. Cell Biol. 156:595-602. doi:10.1083/jcb.200110109
    • (2002) J. Cell Biol. , vol.156 , pp. 595-602
    • Joseph, J.1    Tan, S.H.2    Karpova, T.S.3    McNally, J.G.4    Dasso, M.5
  • 27
    • 0037151026 scopus 로고    scopus 로고
    • A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain
    • doi:10.1074/jbc.C200198200
    • Kane, S., H. Sano, S.C. Liu, J.M. Asara, W.S. Lane, C.C. Garner, and G.E. Lienhard. 2002. A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. J. Biol. Chem. 277:22115-22118. doi:10.1074/jbc.C200198200
    • (2002) J. Biol. Chem. , vol.277 , pp. 22115-22118
    • Kane, S.1    Sano, H.2    Liu, S.C.3    Asara, J.M.4    Lane, W.S.5    Garner, C.C.6    Lienhard, G.E.7
  • 28
    • 0242622698 scopus 로고    scopus 로고
    • Analysis of the cell cycle using Xenopus egg extracts
    • K. M. Yamada, editor. John Wiley & Sons, Inc., New York, NY
    • Kornbluth, S., J. Yang, and M. Powers. 2001. Analysis of the cell cycle using Xenopus egg extracts. In Current Protocols in Cell Biology. K. M. Yamada, editor. John Wiley & Sons, Inc., New York, NY. 11.11.1-11.11.13.
    • (2001) Current Protocols in Cell Biology
    • Kornbluth, S.1    Yang, J.2    Powers, M.3
  • 29
    • 63049138013 scopus 로고    scopus 로고
    • SUMO modification of DNA topoisomerase II: Trying to get a CENse of it all
    • doi:10.1016/j.dnarep.2009.01.004
    • Lee, M.T., and J. Bachant. 2009. SUMO modification of DNA topoisomerase II: trying to get a CENse of it all. DNA Repair (Amst.). 8:557-568. doi:10.1016/j.dnarep.2009.01.004
    • (2009) DNA Repair (Amst.) , vol.8 , pp. 557-568
    • Lee, M.T.1    Bachant, J.2
  • 31
    • 0037059619 scopus 로고    scopus 로고
    • The nucleoporin RanBP2 has SUMO1 E3 ligase activity
    • doi: 10.1016/S0092-8674(01)00633-X
    • Pichler, A., A. Gast, J.S. Seeler, A. Dejean, and F. Melchior. 2002. The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell. 108:109-120. doi: 10.1016/S0092-8674(01)00633-X
    • (2002) Cell. , vol.108 , pp. 109-120
    • Pichler, A.1    Gast, A.2    Seeler, J.S.3    Dejean, A.4    Melchior, F.5
  • 32
    • 13544254815 scopus 로고    scopus 로고
    • Topoisomerase II: Untangling its contribution at the centromere
    • doi:10.1023/B: CHRO.0000036608.91085.d1
    • Porter, A.C., and C.J. Farr. 2004. Topoisomerase II: untangling its contribution at the centromere. Chromosome Res. 12:569-583. doi:10.1023/B: CHRO.0000036608.91085.d1
    • (2004) Chromosome Res. , vol.12 , pp. 569-583
    • Porter, A.C.1    Farr, C.J.2
  • 33
    • 0029961651 scopus 로고    scopus 로고
    • DNA transport by a type II topoisomerase: Direct evidence for a two-gate mechanism
    • doi:10.1073/pnas.93.9.4057
    • Roca, J., J.M. Berger, S.C. Harrison, and J.C. Wang. 1996. DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. Proc. Natl. Acad. Sci. USA. 93:4057-4062. doi:10.1073/pnas.93.9.4057
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4057-4062
    • Roca, J.1    Berger, J.M.2    Harrison, S.C.3    Wang, J.C.4
  • 34
    • 77957770103 scopus 로고    scopus 로고
    • Rod/Zw10 complex is required for PIASydependent centromeric SUMOylation
    • doi:10.1074/jbc.M110.153817
    • Ryu, H., and Y. Azuma. 2010. Rod/Zw10 complex is required for PIASydependent centromeric SUMOylation. J. Biol. Chem. 285:32576-32585. doi:10.1074/jbc.M110.153817
    • (2010) J. Biol. Chem. , vol.285 , pp. 32576-32585
    • Ryu, H.1    Azuma, Y.2
  • 35
    • 77951985475 scopus 로고    scopus 로고
    • PIASy mediates SUMO-2/3 conjugation of poly(ADPribose) polymerase 1 (PARP1) on mitotic chromosomes
    • doi:10.1074/jbc.M109.074583
    • Ryu, H., G. Al-Ani, K. Deckert, D. Kirkpatrick, S.P. Gygi, M. Dasso, and Y. Azuma. 2010. PIASy mediates SUMO-2/3 conjugation of poly(ADPribose) polymerase 1 (PARP1) on mitotic chromosomes. J. Biol. Chem. 285:14415-14423. doi:10.1074/jbc.M109.074583
    • (2010) J. Biol. Chem. , vol.285 , pp. 14415-14423
    • Ryu, H.1    Al-Ani, G.2    Deckert, K.3    Kirkpatrick, D.4    Gygi, S.P.5    Dasso, M.6    Azuma, Y.7
  • 36
    • 28844455588 scopus 로고    scopus 로고
    • Recent advances in understanding structure-function relationships in the type II topoisomerase mechanism
    • doi:10.1042/BST20051465
    • Schoeffler, A.J., and J.M. Berger. 2005. Recent advances in understanding structure-function relationships in the type II topoisomerase mechanism. Biochem. Soc. Trans. 33:1465-1470. doi:10.1042/BST20051465
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 1465-1470
    • Schoeffler, A.J.1    Berger, J.M.2
  • 37
    • 50649101663 scopus 로고    scopus 로고
    • DNA topoisomerases: Harnessing and constraining energy to govern chromosome topology
    • Schoeffler, A.J., and J.M. Berger. 2008. DNA topoisomerases: harnessing and constraining energy to govern chromosome topology. Q. Rev. Biophys. 41:41-101.
    • (2008) Q. Rev. Biophys. , vol.41 , pp. 41-101
    • Schoeffler, A.J.1    Berger, J.M.2
  • 38
    • 33644761942 scopus 로고    scopus 로고
    • SIZ1/ SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II
    • doi:10.1534/ genetics.105.047167
    • Takahashi, Y., V. Yong-Gonzalez, Y. Kikuchi, and A. Strunnikov. 2006. SIZ1/ SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II. Genetics. 172:783-794. doi:10.1534/ genetics.105.047167
    • (2006) Genetics , vol.172 , pp. 783-794
    • Takahashi, Y.1    Yong-Gonzalez, V.2    Kikuchi, Y.3    Strunnikov, A.4
  • 39
    • 0037043338 scopus 로고    scopus 로고
    • Rapid exchange of mammalian topoisomerase II α at kinetochores and chromosome arms in mitosis
    • doi:10.1083/jcb.200202053
    • Tavormina, P.A., M.G. Côme, J.R. Hudson, Y.Y. Mo, W.T. Beck, and G.J. Gorbsky. 2002. Rapid exchange of mammalian topoisomerase II α at kinetochores and chromosome arms in mitosis. J. Cell Biol. 158:23-29. doi:10.1083/jcb.200202053
    • (2002) J. Cell Biol. , vol.158 , pp. 23-29
    • Tavormina, P.A.1    Côme, M.G.2    Hudson, J.R.3    Mo, Y.Y.4    Beck, W.T.5    Gorbsky, G.J.6
  • 40
    • 2942715083 scopus 로고    scopus 로고
    • A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells
    • doi:10.1074/jbc.M312314200
    • Walker, J.V., K.C. Nitiss, L.H. Jensen, C. Mayne, T. Hu, P.B. Jensen, M. Sehested, T. Hsieh, and J.L. Nitiss. 2004. A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells. J. Biol. Chem. 279:25947-25954. doi:10.1074/jbc.M312314200
    • (2004) J. Biol. Chem. , vol.279 , pp. 25947-25954
    • Walker, J.V.1    Nitiss, K.C.2    Jensen, L.H.3    Mayne, C.4    Hu, T.5    Jensen, P.B.6    Sehested, M.7    Hsieh, T.8    Nitiss, J.L.9
  • 41
    • 41149168802 scopus 로고    scopus 로고
    • Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation
    • doi:10.1007/ s00412-007-0131-7
    • Wang, L.H., T. Schwarzbraun, M.R. Speicher, and E.A. Nigg. 2008. Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma. 117:123-135. doi:10.1007/ s00412-007-0131-7
    • (2008) Chromosoma , vol.117 , pp. 123-135
    • Wang, L.H.1    Schwarzbraun, T.2    Speicher, M.R.3    Nigg, E.A.4
  • 42
    • 77149154656 scopus 로고    scopus 로고
    • Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division
    • doi:10.1242/jcs.058255
    • Wang, L.H., B. Mayer, O. Stemmann, and E.A. Nigg. 2010. Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. J. Cell Sci. 123:806-813. doi:10.1242/jcs.058255
    • (2010) J. Cell Sci. , vol.123 , pp. 806-813
    • Wang, L.H.1    Mayer, B.2    Stemmann, O.3    Nigg, E.A.4
  • 43
    • 33846636841 scopus 로고    scopus 로고
    • The role of SUMO in chromosome segregation
    • doi:10.1007/s00412-006-0079-z
    • Watts, F.Z. 2007. The role of SUMO in chromosome segregation. Chromosoma. 116:15-20. doi:10.1007/s00412-006-0079-z
    • (2007) Chromosoma , vol.116 , pp. 15-20
    • Watts, F.Z.1
  • 44
    • 33747838835 scopus 로고    scopus 로고
    • SUMOsp: A web server for sumoylation site prediction
    • doi: 10.1093/nar/gkl207
    • Xue, Y., F. Zhou, C. Fu, Y. Xu, and X. Yao. 2006. SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res. 34:W254-W257. doi: 10.1093/nar/gkl207
    • (2006) Nucleic Acids Res. , vol.34
    • Xue, Y.1    Zhou, F.2    Fu, C.3    Xu, Y.4    Yao, X.5
  • 45
    • 67649484355 scopus 로고    scopus 로고
    • Clearing the way for mitosis: Is cohesin a target?
    • doi:10.1038/nrm2712
    • Yanagida, M. 2009. Clearing the way for mitosis: is cohesin a target? Nat. Rev. Mol. Cell Biol. 10:489-496. doi:10.1038/nrm2712
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 489-496
    • Yanagida, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.