Design and generation of MLPA probe sets for combined copy number and small-mutation analysis of human genes: EGFR as an example

TheScientificWorldJournal

Volumn 10, Issue , 2010, Pages 2003-2018

  Marcinkowska, Malgorzata ^a   Wong, Kwok Kin ^b,c   Kwiatkowski, David J ^d   Kozlowski, Piotr ^a  

^a INSTITUTE OF BIOORGANIC CHEMISTRY   (Poland)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c DANA FARBER HARVARD CANCER CENTER   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Amplification; CNV; Copy number variation; EGFR; Large deletion; MLPA; Multiplex ligation dependent probe amplification; Mutation detection

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FORMAMIDE; GENOMIC DNA; OLIGONUCLEOTIDE; POLYMER;

AMPLICON; ANALYTICAL EQUIPMENT; CAPILLARY ELECTROPHORESIS; GENE DOSAGE; GENE MUTATION; GENE SEQUENCE; HUMAN; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; POLYMERASE CHAIN REACTION; REVIEW; SYNTHESIS; ARTICLE; GENE DELETION; GENETICS; LIGASE CHAIN REACTION; METHODOLOGY; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; REPRODUCIBILITY;

BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; GENE DOSAGE; HUMANS; LIGASE CHAIN REACTION; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE PROBES; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRODUCIBILITY OF RESULTS; SEQUENCE DELETION;

EID: 78349262236     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2010.195     Document Type: Review

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