Glucosamine and osteoarthritis: Effect size is encouraging

BMJ (Online)

Volumn 341, Issue 7781, 2010, Pages 1110-

  Pelletier, Jean Pierre ^a,b   Hochberg, Marc C ^a,c   Du Souich, Patrick ^b   Kahan, André ^a,d   Michel, Beat A ^e  

^a Department of Medicine ^*  (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN; CHONDROITIN SULFATE; GLUCOSAMINE; GLUCOSAMINE SULFATE; PARACETAMOL; PLACEBO; ANTIINFLAMMATORY AGENT;

CLINICAL RESEARCH; EFFECT SIZE; KNEE ARTHROPLASTY; LETTER; OSTEOARTHRITIS; PAIN ASSESSMENT; PRIORITY JOURNAL; STUDY DESIGN; HUMAN; NOTE; SAMPLE SIZE;

ANTI-INFLAMMATORY AGENTS; CHONDROITIN; GLUCOSAMINE; HUMANS; OSTEOARTHRITIS; SAMPLE SIZE;

EID: 78349251938     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.c6328     Document Type: Letter

References (5)

1. Wandel S, Jüni P, Tendal B, Nüesch E, Villiger PM, Welton NJ, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010;341:c4675. (16 September.)
2. Committee for Products for Medicinal Use. Guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis. CPMP/EWP/784/97 Rev 1; 23 April 2009.
3. Michel BA, Stucki G, Frey D, De Vathaire F, Vignon E, Bruehlmann P, et al. Chondroitins 4 and 6 sulfate in osteoarthritis of the knee: a randomized, controlled trial. Arthritis Rheum 2005;52:779-86.
4. Hochberg MC. Structure-modifying effects of chondroitin sulfate in knee osteoarthritis: an updated meta-analysis of randomized placebo-controlled trials of 2-year duration. Osteoarthritis Cartilage2010;18 (suppl 1):S28-31.
5. Bruyere O, Pavelka K, Rovati LC, Gatterová J, Giacovelli G, Olejarová M, et al. Total joint replacement after glucosamine sulfate treatment in knee osteoarthritis: results of a mean 8-year observation of patients from two previous 3-year, randomised, placebo-controlled trials. Osteoarthritis Cartilage 2008;16:254-60.