From predisposition to illness: Genetically sensitive intermediate pathways to mood disorders

British Journal of Psychiatry

Volumn 197, Issue 5, 2010, Pages 341-342

  Duffy, Anne ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; HYDROCORTISONE; SEROTONIN TRANSPORTER;

ADOLESCENT; DEPRESSION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETICS; HIGH RISK POPULATION; HUMAN; MOOD DISORDER; REVIEW; RISK FACTOR;

ADOLESCENT; CHILD; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MOOD DISORDERS; YOUNG ADULT;

EID: 78249285971     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.bp.110.079665     Document Type: Review

References (10)

1. Akiskal HS. Interaction of biologic and psychologic factors in the origin of depressive disorders. Acta Psychiatr Scand Suppl 1985; 319: 131-9.
2. McMahon FJ, Akula N, Schulze TG, Muglia P, Tozzi F, Detera-Wadleigh SD, et al. Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet 2010; 42: 128-31.
3. Grof P, Duffy A, Alda M, Hajek T. Lithium response across generations. Acta Psychiatr Scand 2009; 120: 378-85.
4. Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010; 167: 509-27.
5. Goodyer IM, Bacon A, Ban M, Croudace T, Herbert J. Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents. Br J Psychiatry 2009; 195: 39-45.
6. Szyf M, McGowan P, Meaney MJ. The social environment and the epigenome. Environ Mol Mutagen 2008; 49: 46-60.
7. Halligan SL, Herbert J, Goodyer I, Murray L. Disturbances in morning cortisol secretion in association with maternal postnatal depression predict subsequent depressive symptomatology in adolescents. Biol Psychiatry 2007; 62: 40-6.
8. Deshauer D, Grof E, Alda M, Grof P. Patterns of DST positivity in remitted affective disorders. Biol Psychiatry 1999; 45: 1023-9.
9. Ellenbogen MA, Santo JB, Linnen AM, Walker CD, Hodgins S. High cortisol levels in the offspring of parents with bipolar disorder during two weeks of daily sampling. Bipolar Disord 2010; 12: 77-86.
10. Duffy A, Alda M, Hajek T, Sherry SB, Grof P. Early stages in the development of bipolar disorder. J Affect Disord 2010; 121: 127-35.