In vivo evaluation of MMP sensitive high-molecular weight HA-based hydrogels for bone tissue engineering

Journal of Biomedical Materials Research - Part A

Volumn 95, Issue 3 A, 2010, Pages 673-681

  Kim, Jungju ^a,b   Kim, In Sook ^c   Cho, Tae Hyung ^c   Kim, Ho Chul ^b   Yoon, So Jeong ^a,b   Choi, Jaesoon ^b   Park, Yongdoo ^a,b   Sun, Kyung ^a,b   Hwang, Soon Jung ^c  

^a Korea University College of Medicine   (South Korea)

^b Korea University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Bone; Hyaluronic acid; Hydrogel; Matrix metalloproteinase; Tissue engineering

Indexed keywords

ALKALINE PHOSPHATASE; ARG GLY ASPS; BINDING DOMAIN; BONE TISSUE ENGINEERING; CALVARIAL DEFECTS; CELL ADHESION PEPTIDES; CELL SPREADING; CROSSLINKER; EXTRACELLULAR MATRICES; GENE EXPRESSION ANALYSIS; HIGH MOLECULAR WEIGHT; HUMAN MESENCHYMAL STEM CELLS (HMSCS); HYALURONIC ACID; HYALURONIC ACIDS; IMMOBILIZED CELLS; IN-VITRO; IN-VIVO; INTEGRINS; MATRIX METALLOPROTEINASES; MATURE BONE; MICROCOMPUTED TOMOGRAPHY; OSTEOCALCIN; OSTEOPONTIN; REGENERATION ACTIVITY; RGD PEPTIDE; SWELLING RATIO; TISSUE REMODELING; WEIGHT PERCENTAGES;

ADHESION; BIOMECHANICS; BONE; CELL ADHESION; CELL CULTURE; COMPUTERIZED TOMOGRAPHY; ENZYME ACTIVITY; GENE EXPRESSION; MECHANICAL PROPERTIES; ORGANIC ACIDS; PEPTIDES; PHOSPHATASES; STEM CELLS; TISSUE ENGINEERING;

HYDROGELS;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; GELATINASE A; HYALURONIC ACID; MATRIX METALLOPROTEINASE; OSTEOCALCIN; OSTEOPONTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE REGENERATION; BONE TISSUE; CELL SPREADING; GENE EXPRESSION; HUMAN; HUMAN CELL; HYDROGEL; HYPEROSTOSIS; IMMOBILIZED CELL; IN VIVO STUDY; MALE; MESENCHYME CELL; NONHUMAN; PHYSICAL CHEMISTRY; RAT; TISSUE ENGINEERING; YOUNG MODULUS;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE AND BONES; BONE REGENERATION; CELL CULTURE TECHNIQUES; CELLS, CULTURED; ELASTICITY; GENE EXPRESSION; HUMANS; HYALURONIC ACID; HYDROGELS; MALE; MATERIALS TESTING; MATRIX METALLOPROTEINASES; MESENCHYMAL STEM CELLS; MOLECULAR WEIGHT; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; VISCOSITY;

EID: 78249279058     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32884     Document Type: Article

References (43)

1. Lutolf MP, Hubbell JA,. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005; 23: 47 -55.
2. Batorsky A, Liao J, Lund AW, Plopper GE, Stegemann JP,. Encapsulation of adult human mesenchymal stem cells within collagen-agarose microenvironments. Biotechnol Bioeng 2005; 92: 492 -500.
3. Laurent TC, Laurent UB, Fraser JR,. Functions of hyaluronan. Ann Rheum Dis 1995; 54: 429 -432.
4. Allison DD, Grande-Allen KJ,. Review. Hyaluronan: A powerful tissue engineering tool. Tissue Eng 2006; 12: 2131 -2140.
5. Evanko SP, Angello JC, Wight TN,. Formation of hyaluronan-and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1999; 19: 1004 -1013.
6. Itano N, Atsumi F, Sawai T, Yamada Y, Miyaishi O, Senga T, Hamaguchi M, Kimata K,. Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration. Proc Natl Acad Sci USA 2002; 99: 3609 -3614.
7. Trochon V, Mabilat C, Bertrand P, Legrand Y, Smadja-Joffe F, Soria C, Delpech B, Lu H,. Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro. Int J Cancer 1996; 66: 664 -668.
8. Karvinen S, Pasonen-Seppanen S, Hyttinen JM, Pienimaki JP, Torronen K, Jokela TA, Tammi MI, Tammi R,. Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 and 3. J Biol Chem 2003; 278: 49495 -49504.
9. Trabucchi E, Pallotta S, Morini M, Corsi F, Franceschini R, Casiraghi A, Pravettoni A, Foschi D, Minghetti P,. Low molecular weight hyaluronic acid prevents oxygen free radical damage to granulation tissue during wound healing. Int J Tissue React 2002; 24: 65 -71.
10. West DC, Hampson IN, Arnold F, Kumar S,. Angiogenesis induced by degradation products of hyaluronic acid. Science 1985; 228: 1324 -1326.
11. Slevin M, Krupinski J, Gaffney J, Matou S, West D, Delisser H, Savani RC, Kumar S,. Hyaluronan-mediated angiogenesis in vascular disease: Uncovering RHAMM and CD44 receptor signaling pathways. Matrix Biol 2007; 26: 58 -68.
12. Entwistle J, Hall CL, Turley EA,. HA receptors: Regulators of signalling to the cytoskeleton. J Cell Biochem 1996; 61: 569 -577.
13. English NM, Lesley JF, Hyman R,. Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding. Cancer Res 1998; 58: 3736 -3742.
14. Zhang S, Chang MC, Zylka D, Turley S, Harrison R, Turley EA,. The hyaluronan receptor RHAMM regulates extracellular-regulated kinase. J Biol Chem 1998; 273: 11342 -11348.
15. Bastow ER, Byers S, Golub SB, Clarkin CE, Pitsillides AA, Fosang AJ,. Hyaluronan synthesis and degradation in cartilage and bone. Cell Mol Life Sci 2008; 65: 395 -413.
16. Ariyoshi W, Takahashi T, Kanno T, Ichimiya H, Takano H, Koseki T, Nishihara T,. Mechanisms involved in enhancement of osteoclast formation and function by low molecular weight hyaluronic acid. J Biol Chem 2005; 280: 18967 -18972.
17. Falconi D, Aubin JE,. LIF inhibits osteoblast differentiation at least in part by regulation of HAS2 and its product hyaluronan. J Bone Miner Res 2007; 22: 1289 -1300.
18. Prestwich GD, Marecak DM, Marecek JF, Vercruysse KP, Ziebell MR,. Controlled chemical modification of hyaluronic acid: Synthesis, applications, and biodegradation of hydrazide derivatives. J Control Release 1998; 53: 93 -103.
19. Bulpitt P, Aeschlimann D,. New strategy for chemical modification of hyaluronic acid: Preparation of functionalized derivatives and their use in the formation of novel biocompatible hydrogels. J Biomed Mater Res 1999; 47: 152 -169.
20. Baier Leach J, Bivens KA, Patrick CW Jr, Schmidt CE,. Photocrosslinked hyaluronic acid hydrogels: Natural, biodegradable tissue engineering scaffolds. Biotechnol Bioeng 2003; 82: 578 -589.
21. Park YD, Tirelli N, Hubbell JA,. Photopolymerized hyaluronic acid-based hydrogels and interpenetrating networks. Biomaterials 2003; 24: 893 -900.
22. Kim GW, Choi YJ, Kim MS, Park Y, Lee KB, Kim IS, Hwang SJ, Noh I,. Synthesis and evaluation of hyaluronic acid -poly(ethylene oxide) hydrogel via Michael-type addition reaction. Curr Appl Phys 2007; 7 (suppl 1): e28 -e32.
23. Kim J, Kim IS, Cho TH, Lee KB, Hwang SJ, Tae G, Noh I, Lee SH, Park Y, Sun K,. Bone regeneration using hyaluronic acid-based hydrogel with bone morphogenic protein-2 and human mesenchymal stem cells. Biomaterials 2007; 28: 1830 -1837.
24. Kim J, Park Y, Tae G, Lee KB, Hwang CM, Hwang SJ, Kim IS, Noh I, Sun K,. Characterization of low-molecular-weight hyaluronic acid-based hydrogel and differential stem cell responses in the hydrogel microenvironments. J Biomed Mater Res A 2009; 88: 967 -975.
25. Zhong SP, Campoccia D, Doherty PJ, Williams RL, Benedetti L, Williams DF,. Biodegradation of hyaluronic acid derivatives by hyaluronidase. Biomaterials 1994; 15: 359 -365.
26. Nwomeh BC, Liang HX, Diegelmann RF, Cohen IK, Yager DR,. Dynamics of the matrix metalloproteinases MMP-1 and MMP-8 in acute open human dermal wounds. Wound Repair Regen 1998; 6: 127 -134.
27. Bai S, Thummel R, Godwin AR, Nagase H, Itoh Y, Li L, Evans R, McDermott J, Seiki M, Sarras MP Jr,. Matrix metalloproteinase expression and function during fin regeneration in zebrafish: Analysis of MT1-MMP. MMP2 and TIMP2. Matrix Biol 2005; 24: 247 -260.
28. Kasper G, Glaeser JD, Geissler S, Ode A, Tuischer J, Matziolis G, Perka C, Duda GN,. Matrix metalloprotease activity is an essential link between mechanical stimulus and mesenchymal stem cell behavior. Stem Cells 2007; 25: 1985 -1994.
29. Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB, Hubbell JA,. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics. Proc Natl Acad Sci USA 2003; 100: 5413 -5418.
30. Zisch AH, Lutolf MP, Ehrbar M, Raeber GP, Rizzi SC, Davies N, Schmokel H, Bezuidenhout D, Djonov V, Zilla P, Hubbell JA,. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth. FASEB J 2003; 17: 2260 -2262.
31. Seliktar D, Zisch AH, Lutolf MP, Wrana JL, Hubbell JA,. MMP-2 sensitive. VEGF-bearing bioactive hydrogels for promotion of vascular healing. J Biomed Mater Res A 2004; 68: 704 -716.
32. Park Y, Lutolf MP, Hubbell JA, Hunziker EB, Wong M,. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Eng 2004; 10: 515 -522.
33. Levesque SG, Shoichet MS,. Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels. Bioconjug Chem 2007; 18: 874 -885.
34. Kim J, Park Y, Tae G, Lee KB, Hwang SJ, Kim IS, Noh I, Sun K,. Synthesis and characterization of matrix metalloprotease sensitive-low molecular weight hyaluronic acid based hydrogels. J Mater Sci Mater Med 2008; 19: 3311 -3318.
35. Hong SR, Chong MS, Lee SB, Lee YM, Song KW, Park MH, Hong SH,. Biocompatibility and biodegradation of cross-linked gelatin/hyaluronic acid sponge in rat subcutaneous tissue. J Biomater Sci Polym Ed 2004; 15: 201 -214.
36. Stites J, Wessels D, Uhl A, Egelhoff T, Shutt D, Soll DR,. Phosphorylation of the Dictyostelium myosin II heavy chain is necessary for maintaining cellular polarity and suppressing turning during chemotaxis. Cell Motil Cytoskeleton 1998; 39: 31 -51.
37. Park Y, Sugimoto M, Watrin A, Chiquet M, Hunziker EB,. BMP-2 induces the expression of chondrocyte-specific genes in bovine synovium-derived progenitor cells cultured in three-dimensional alginate hydrogel. Osteoarthritis Cartilage. 2005; 13: 527 -536.
38. Yoon SJ, Fang YH, Lim CH, Kim BS, Son HS, Park Y, Sun K,. Regeneration of ischemic heart using hyaluronic acid-based injectable hydrogel. J Biomed Mater Res B Appl Biomater 2009; 91: 163 -171.
39. Park J, Lim E, Back S, Na H, Park Y, Sun K,. Nerve regeneration following spinal cord injury using matrix metalloproteinase-sensitive, hyaluronic acid-based biomimetic hydrogel scaffold containing brain-derived neurotrophic factor. J Biomed Mater Res A 2010; 93: 1091 -1099.
40. Lutolf MP, Tirelli N, Cerritelli S, Cavalli L, Hubbell JA,. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjug Chem 2001; 12: 1051 -1056.
41. Kim J, Park Y, Tae G, Lee KB, Hwang CM, Hwang SJ, Kim IS, Noh I, Sun K,. Characterization of low-molecular-weight hyaluronic acid-based hydrogel and differential stem cell responses in the hydrogel microenvironments. J Biomed Mater Res A 2009; 88: 967 -975.
42. Saha K, Keung AJ, Irwin EF, Li Y, Little L, Schaffer DV, Healy KE,. Substrate modulus directs neural stem cell behavior. Biophys J 2008; 95: 4426 -4438.
43. Qu ZH, Wang HJ, Tang TT, Zhang XL, Wang JY, Dai KR,. Evaluation of the zein/inorganics composite on biocompatibility and osteoblastic differentiation. Acta Biomater 2008; 4: 1360 -1368.