Strong detrimental effect of a minute enantiomeric impurity of a chiral selector on the enantioselectivity factor

Angewandte Chemie - International Edition

Volumn 49, Issue 42, 2010, Pages 7742-7744

  Levkin, Pavel A ^b   Maier, Norbert M ^a   Schurig, Volker ^b   Lindner, Wolfgang ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Chiral chromatography; Chiral selectors; Enantiomer separation; Enantioselectivity; Liquid chromatography

Indexed keywords

CHIRAL CHROMATOGRAPHY; CHIRAL SELECTOR; DETRIMENTAL EFFECTS; ENANTIOMER SEPARATION; ENANTIOMERIC PURITY; ENANTIOSEPARATIONS;

CHIRALITY; ENANTIOMERS; ENANTIOSELECTIVITY; IMPURITIES; LIQUIDS;

LIQUID CHROMATOGRAPHY;

AMINO ACID; DRUG; NITROBENZENE DERIVATIVE; QUINIDINE; QUININE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; STEREOISOMERISM;

AMINO ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINITROBENZENES; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; QUINIDINE; QUININE; STEREOISOMERISM;

EID: 78249273303     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201002215     Document Type: Article

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