Expression level of augmenter of liver regeneration in patients with hepatic failure and hepatocellular carcinoma

Hepatobiliary and Pancreatic Diseases International

Volumn 9, Issue 5, 2010, Pages 492-498

  Yu, Hai Ying ^a   Xiang, Dai Rong ^a   Huang, Hai Jun ^a   Li, Jun ^a   Sheng, Ji Fang ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Chronic hepatitis B; Expression level; Hepatic failure; Hepatocellular carcinoma; Liver regeneration

Indexed keywords

AUGMENTER OF LIVER REGENERATION; BETA ACTIN; IMMUNOGLOBULIN G; MESSENGER RNA; POLYCLONAL ANTIBODY; POLYPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL REGENERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPATITIS B; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL; LIVER CELL CARCINOMA; LIVER FAILURE; LIVER REGENERATION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROGNOSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATITIS B; HUMANS; LIVER FAILURE; LIVER NEOPLASMS; LIVER REGENERATION; PROGNOSIS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 78249272699     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Pawlowski R, Jura J. ALR and liver regeneration. Mol Cell Biochem 2006;288:159-169.
2. de Juan C, Benito M, Alvarez A, Fabregat I. Differential proliferative response of cultured fetal and regenerating hepatocytes to growth factors and hormones. Exp Cell Res 1992;202:495-500.
3. Gandhi CR, Kuddus R, Subbotin VM, Prelich J, Murase N, Rao AS, et al. A fresh look at augmenter of liver regeneration in rats. Hepatology 1999;29:1435-1445.
4. Thasler WE, Schlott T, Thelen P, Hellerbrand C, Bataille F, Lichtenauer M, et al. Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma. Histopathology 2005;47:57-66.
5. Tang L, Sun H, Zhang L, Guo H, Zhang L, Liu Q. Inhibitory effect of blocking expression of human augmenter of liver regeneration (hALR) on proliferation of hepatocellular carcinoma cell line HepG2. Ai Zheng 2006;25:671-676.
6. Tang L, Sun H, Zhang L, Guo H, Chen XH, Deng JC, et al. Effects of anti-human augmenter of liver regeneration monoclonal antibody on proliferation of HepG2 cells in vitro. J Chongqing Med Univ 2005;30:7-9, 17.
7. Elias E. Liver failure and liver disease. Hepatology 2006;43: S239-242.
8. Sheng J, Yu H, Li J, Sheng G, Zhou L, Lu Y. Cloning and expression of the human augmenter of liver regeneration at low temperature in Escherichia coli. J Biochem Biophys Methods 2007;70:465-470.
9. Li J, Li LJ, Cao HC, Sheng GP, Yu HY, Xu W, et al. Establishment of highly differentiated immortalized human hepatocyte line with simian virus 40 large tumor antigen for liver based cell therapy. ASAIO J 2005;51:262-268.
10. LaBrecque DR, Pesch LA. Preparation and partial characterization of hepatic regenerative stimulator substance (SS) from rat liver. J Physiol 1975;248:273-284.
11. Hagiya M, Francavilla A, Polimeno L, Ihara I, Sakai H, Seki T, et al. Cloning and sequence analysis of the rat augmenter of liver regeneration (ALR) gene: expression of biologically active recombinant ALR and demonstration of tissue distribution. Proc Natl Acad Sci U S A 1994;91:8142-8146.
12. Giorda R, Hagiya M, Seki T, Shimonishi M, Sakai H, Michaelson J, et al. Analysis of the structure and expression of the augmenter of liver regeneration (ALR) gene. Mol Med 1996;2:97-108.
13. Riordan SM, Williams R. Mechanisms of hepatocyte injury, multiorgan failure, and prognostic criteria in acute liver failure. Semin Liver Dis 2003;23:203-215.
14. Schirmacher P, Geerts A, Pietrangelo A, Dienes HP, Rogler CE. Hepatocyte growth factor/hepatopoietin A is expressed in fat-storing cells from rat liver but not myofibroblast-like cells derived from fat-storing cells. Hepatology 1992;15:5-11.
15. Vujanovic NL, Polimeno L, Azzarone A, Francavilla A, Chambers WH, Starzl TE, et al. Changes of liver-resident NK cells during liver regeneration in rats. J Immunol 1995;154: 6324-6238.
16. Tanigawa K, Sakaida I, Masuhara M, Hagiya M, Okita K. Augmenter of liver regeneration (ALR) may promote liver regeneration by reducing natural killer (NK) cell activity in human liver diseases. J Gastroenterol 2000;35:112-119.
17. Bruix J, Llovet JM. Prognostic prediction and treatment strategy in hepatocellular carcinoma. Hepatology 2002;35: 519-524.
18. Campbell JS, Johnson MM, Bauer RL, Hudkins KL, Gilbertson DG, Riehle KJ, et al. Targeting stromal cells for the treatment of platelet-derived growth factor C-induced hepatocellular carcinogenesis. Differentiation 2007;75:843-852.
19. Fausto N, Webber EM. Mechanisms of growth regulation in liver regeneration and hepatic carcinogenesis. Prog Liver Dis 1993;11:115-137.
20. El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007;132:2557-2576.
21. Sun H, Yu HF, Wu CX, Guan XQ, Liu Q. Expression of augmenter of liver regeneration in hepatic tumor cells and its clinical significance. Zhonghua Gan Zang Bing Za Zhi 2005; 13:205-208.