Isolation and characterization of cytotoxic compounds from Euphorbia cornigera Boiss.

Journal of Asian Natural Products Research

Volumn 12, Issue 11, 2010, Pages 985-991

  Baloch, Imam Bakhsh ^a   Baloch, Musa Kaleem ^a  

^a GOMAL UNIVERSITY   (Pakistan)

Author keywords

cytotoxicity; Euphorbia cornigera Boiss; Euphorbiaceae; ingenol

Indexed keywords

13 O DODECANOYL 20 O HEXANOYLINGENOL; 3 O (2,3 DIMETHYLBUTANOYL) 13 O DODECANOYL 20 O HEXADECANOYLINGENOL; 3 O (2,3 DIMETHYLBUTANOYL) 13 O DODECANOYL 20 O TETRADECANOYLINGENOL; 3 O DECANOYL 20 O HEXANOYLINGENOL; AMRUBICIN; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; EUPHORBIA CORNIGERA; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; INFRARED SPECTROSCOPY; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; SHOOT; STEREOCHEMISTRY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; EUPHORBIA; HT29 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PAKISTAN; PLANT STEMS; PLANTS, MEDICINAL;

EUPHORBIA; EUPHORBIACEAE;

EID: 78249269119     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020.2010.512007     Document Type: Article

References (16)

1. M. Shoeb, Bangladesh J. Pharmacol. 1, 35 (Minireview), and references cited therein (2006)
2. I.B. Baloch, M.K. Baloch, and Q.N. Saqib, Planta Med. 72, 830 (2006).
3. I.B. Baloch, M.K. Baloch, and Q.N. Saqib, Eur. J. Med. Chem. 43, 274 (2008).
4. Y.B. Wang, R. Huang, H.B. Wang, H.Z. Jin, L.G. Lou, and G.W. Qin, J. Nat. Prod. 69, 967 (2006).
5. L. Su, S.G. Feng, L. Qiao, Y.Z. Zhou, R.P. Yang, and Y.H. Pei, J. Asian Nat. Prod. Res. 11, 38 (2009).
6. J.W. Yarbro, The scientific basis ofcancer chemotherapy, in The Chemotherapy Source Book, edited by M.C. Perry (Williams & Wilkins, Baltimore, MD, 1992), p. 2.
7. B.A. Chabner, Anti-cancer drugs, in Cancer: Principles and Practice, edited by V.T. DeVita Jr., S. Hellman, A.S. Rosenberg, 4th ed. (Lippincott, Philadel-phia, MD, 1991), Chap. 18, p. 325.
8. J.M. Jessup, L.S. McGinnis, D.P. Winche-ster, H. Eyre, A. Fremgen, G.P. Murphy, and H.R. Menck, CA Cancer J. Clin. 46, 185 (1996).
9. I.B. Baloch, M.K. Baloch, and Q.N. Saqib, Helv. Chim. Acta 88, 3145 (2005).
10. I.B. Baloch, M.K. Baloch, Q.N. Saqib, and M. Ahmed, Chem. Pharm. Med. J. Int. 2, 107 (2004).
11. I.B. Baloch, and M.K. Baloch, J. Asian Nat. Prod. Res. 12, 600 (2010)
12. I.B. Baloch, M.K. Baloch, and A.K. Baloch, Planta Med. 76, 809 (2010).
13. I.B. Baloch, M.K. Baloch, and A.K. Baloch, Eur. J. Med. Chem. 44, 3188 (2009).
14. D. Uemura and Y. Hirata, Tetrahedron Lett. 29, 2529 (1974).
15. T.T. Wu, Y.M. Lin, M. Haruna, D.J. Pan, and T. Shingu, J. Nat. Prod. 54, 823 (1991).
16. Z.Q. Lu, M. Yang, J.Q. Zhang, G.T. Chen, H.L. Huang, S.H. Guan, C. Ma, X. Liu, and D.A. Guo, Phytochemistry 69, 812 (2008).