Reviewe: Genetics and genomics in equine exercise physiology: An overview of the new applications of molecular biology as positive and negative markers of performance and health

Equine Veterinary Journal

Volumn 42, Issue SUPPL. 38, 2010, Pages 561-568

  Barrey, E ^a,b  

^a Val d'Essonne University   (France)

^b UMR1313 GÉNÉTIQUE ANIMALE ET BIOLOGIE INTÉGRATIVE   (France)

Author keywords

DNA; Exercise; Gene; Horse; Microarray; Muscle; RNA; SNP; Transcript

Indexed keywords

EQUIDAE;

EID: 78249251162     PISSN: 04251644     EISSN: 20423306     Source Type: Journal    
DOI: 10.1111/j.2042-3306.2010.00299.x     Document Type: Review

References (43)

1. Barrey, E. and Galloux, P. (1997) Analysis of the equine jumping technique by accelerometry. Equine vet. J., Suppl. 23, 45-49.
2. Barrey, E., Valette, J.P., Jouglin, M., Blouin, C. and Langlois, B. (1999a) Heritability of percentage of fast myosin heavy chains in skeletal muscles and relationship with performance. Equine vet. J., Suppl. 30, 289-292.
3. Barrey, E., Courouce, A., Langlois, B., Blouin, C. and Auvinet, B. (1999b) Genetic component of exercise test parameters in French Trotters: first estimations. In: Conference on Equine Sports Medicine and Science, Ed: A. Lindner, Cordoba. pp 219-224.
4. Barrey, E., Evans, S.E., Evans, D.L., Curtis, R.A., Quinton, R. and Rose, R.J. (2001) Locomotion evaluation for racing in Thoroughbreds. Equine vet. J., Suppl. 33, 99-103.
5. Barrey, E., Desliens, F., Blouin, C. and Langlois, B. (2002a) Heritabilities of gait characteristics: application for breeding in dressage. In: Conference on Equine Sports Medicine and Science 2002, The Elite Dressage and Three-Day-Event Horse, Ed: A. Lindner. pp 91-95.
6. Barrey, E., Desliens, F., Blouin, C. and Langlois, B. (2002b) Mesures du modèle, des allures et du saut des étalons nationaux par la méthode Equimétrix. 27èmes Journées de la Recherche équine, Les Haras Nationaux, Paris. pp 157-176.
7. Barrey, E., Desliens, F., Poirel, D., Biau, S., Lemaire, S., Rivero, J.L. and Langlois, B. (2002c) Early evaluation of dressage ability in different breeds. Equine vet. J., Suppl. 34, 319-324.
8. Barrey, E. (2004) Influence of genetics in equine exercise physiology. 9th Annual Congress, European College of Sport Science, Clermont-Ferrand, Abstracts book. p 119.
9. Barrey, E., Mucher, E., Robert, C., Amiot, F. and Gidrol, X. (2006) Gene expression profiling in blood cells of endurance horses completing competition or disqualified due to metabolic disorder. Equine vet. J., Suppl. 36, 43-49.
10. Barrey, E., Mucher, E., Jeansoule, N., Larcher, T., Guigand, L., Herszberg, B., Chaffaux, S., Guérin, G., Mata, X., Benech, P., Canale, M., Alibert, O., Maltere, P. and Gidrol, X. (2009) Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions. BMC vet. Res. 7, 29.
11. Barrey, E., Bonnamy, B., Barrey, E., Barrey, E.J., Mata, X., Chaffaux, S. and Guérin, G. (2010) Muscular microRNA expressions in healthy and myopathic horses suffering from polysaccharide storage myopathy or recurrent exertional rhabdomyolysis. Equine vet. J., Suppl. In Press.
12. Bray, M.S., Hagberg, J.M., Pérusse, L., Rankinen, T., Roth, S.M., Wolfarth, B. and Bouchard, C. (2009) The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med. Sci. Sports Exerc. 41, 35-73.
13. Calin, G.A. and Croce, C.M. (2006) MicroRNA signatures in human cancers. Nat. Rev. Cancer 6, 857-866.
14. Caetano, A.R., Shiue, Y.L., Lyons, L.A., O'Brien, S.J., Laughlin, T.F., Bowling, A.T. and Murray, J.D. (1999) A comparative gene map of the horse (Equus caballus). Genome Res. 9, 1239-1249.
15. Chowdhary, B.P., Raudsepp, T., Kata, S.R., Goh, G., Millon, L.V., Allan, V., Piumi, F., Guérin, G., Swinburne, J., Binns, M., Lear, T.L., Mickelson, J., Murray, J., Antczak, D.F., Womack, J.E. and Skow, L.C. (2003) The first-generation whole-genome radiation hybrid map in the horse identifies conserved segments in human and mouse genomes. Genome Res. 13, 742-751. Erratum: Genome Res. 13, 1258.
16. Dierks, C., Löhring, K., Lampe, V., Wittwer, C., Drögemüller, C. and Distl, O. (2007) Genome-wide search for markers associated with osteochondrosis in Hanoverian Warmblood horses. Mamm. Genome 18, 739-747.
17. Firshman, A.M., Valberg, S.J., Bender, J.B., Annandale, E.J. and Hayden, D.W. (2006) Comparison of histopathologic criteria and skeletal muscle fixation techniques for the diagnosis of polysaccharide storage myopathy in horses. Vet. Pathol. 43, 257-269.
18. Gu, J., Orr, N., Park, S.D., Katz, L.M., Sulimova, G., Sulimova, G., MacHugh, D.E. and Hill, E.W. (2009) A genome scan for positive selection in Thoroughbred horses. PLoS ONE 4, e5767.
19. Herszberg, B., McCue, M.E., Larcher, T., Mata, X., Vaiman, A., Chaffaux, S., Chérel, Y., Valberg, S.J., Mickelson, J.R. and Guérin, G. (2009) A GYS1 gene mutation is highly associated with polysaccharide storage myopathy in Cob Normand draught horses. Anim. Genet. 40, 94-96.
20. Hill, E.W., Gu, J., Eivers, S.S., Fonseca, R.G., McGivney, B.A., Govindarajan, P., Orr, N., Katz, L.M. and MacHugh, D.A. (2010) Sequence polymorphism in MSTN predicts sprinting ability and racing stamina in Thoroughbred horses. PLoS ONE 5, e8645.
21. Hintz, R.L. (1980) Genetics of performance in the horse. J. anim. Sci. 51, 582-594.
22. Jayr, L. (2009) Predisposition à la rhabdomyolyse d'effort chez le Trotteur Français: Analyse Génomique. Thèse vétérinaire ENV Alfort. Presented 24th September, pp 84.
23. Lampe, V., Dierks, C. and Distl, O. (2009a) Refinement of a quantitative trait locus on equine chromosome 5 responsible for fetlock osteochondrosis in Hanoverian warmblood horses. Anim. Genet. 40, 553-555.
24. Lampe, V., Dierks, C., Komm, K. and Distl, O. (2009b) Identification of a new quantitative trait locus on equine chromosome 18 responsible for osteochondrosis in Hanoverian warmblood horses. J. anim. Sci. 87, 3477-3481.
25. Langlois, B. (1980) Heritability of racing ability in Thoroughbreds - a review. Livestock Prod. Sci. 7, 583-594.
26. Leleu, C., Cotrel, C. and Barrey, E. (2003) Relationships between locomotor test and racing performances in Standardbreds. In: 54th Annual Meeting of the European Association for Animal Production, Horse Production, Rome. Abstract H2.9.
27. McCue, M.E. and Valberg, S.J. (2007) Estimated prevalence of polysaccharide storage myopathy among overtly healthy Quarter Horses in the United States. J. Am. vet. med. Ass. 231, 746-750.
28. McCue, M.E., Ribeiro, W.P. and Valberg, S.J. (2006) Prevalence of polysaccharide storage myopathy in horses with neuromuscular disorders. Equine vet. J., Suppl. 36, 340-344.
29. McCue, M.E., Valberg, S.J., Jackson, M., Borgia, L., Lucio, M. and Mickelson, J.R. (2009) Polysaccharide storage myopathy phenotype in quarter horse-related breeds is modified by the presence of an RYR1 mutation. Neuromuscul.. Disord. 19, 37-43.
30. McCue, M.E., Valberg, S.J., Miller, M.B., Wade, C., DiMauro, S., Akman, H.O. and Mickelson, J.R. (2008) Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis. Genomics 91, 458-466.
31. McGivney, B.A., Eivers, S.S., MacHugh, D.E., MacLeod, J.N., O'Gorman, G.M., Park, S.D., Katz, L.M. and Hill, E.W. (2009) Transcriptional adaptations following exercise in Thoroughbred horse skeletal muscle highlights molecular mechanisms that lead to muscle hypertrophy. BMC Genom. 30, 638.
32. McGowan, C.M., McGowan, T.W. and Patterson-Kane, J.C. (2009) Prevalence of equine polysaccharide storage myopathy and other myopathies in two equine populations in the United Kingdom. Vet. J. 180, 330-336.
33. Milenkovic, D., Oustry-Vaiman, A., Lear, T.L., Billault, A., Mariat, D., Piumi, F., Schibler, L., Cribiu, E. and Guérin, G. (2002) Cytogenetic localization of 136 genes in the horse: comparative mapping with the human genome. Mamm. Genome 13, 524-534.
34. Quiroz-Rothe, E., Novales, M., Aguilera-Tejero, E. and Rivero, J.L. (2002) Polysaccharide storage myopathy in the M. longissimus lumborum of showjumpers and dressage horses with back pain. Equine vet. J. 34, 171-176.
35. Ricard, A., Bruns, E. and Cunningham, E.P. (2000) Genetics of performance traits. In: Genetics of the horse, Eds: A.T. Bowling and A. Ruvinsky, CABI Publishing, New York. pp 411-438.
36. Rivero, J.L. and Barrey, E. (2001) Heritabilities and genetic and phenotypic parameters for gluteus medius muscle fibre type composition, fibre size and capillaries in purebred Spanish horses. Livestock Prod. Sci. 72, 233-241.
37. Saastamoinen, M.T. and Barrey, E. (2000) The genetics of the horse: 16 conformation and physiological traits: Their evaluation and heritability. In: The genetics of the horse, Eds: A.T. Bowling and A. Ruvinsky, CABI Publishing, New York. pp 441-472.
38. Valberg, S.J., Cardinet, G.H. 3rd, Carlson, G.P. and DiMaruro, S. (1992) Polysaccharide storage myopathy associated with recurrent exertional rhabdomyolysis in horses. Neuromusc. Disord. 2, 351-359.
39. Valentine, B.A. and Cooper, B.J. (2005) Incidence of polysaccharide storage myopathy:necropsy study of 225 horses. Vet. Pathol. 42, 823-837.
40. Wade, C.M., Giulotto, E., Sigurdsson, S., Zoli, M., Gnerre, S., Imsland, F., Lear, T.L., Adelson, D.L., Bailey, E., Bellone, R.R., Blöcker, H., Distl, O., Edgar, R.C., Garber, M., Leeb, T., Mauceli, E., MacLeod, J.N., Penedo, M.C., Raison, J.M., Sharpe, T., Vogel, J., Andersson, L., Antczak, D.F., Biagi, T., Binns, M.M., Chowdhary, B.P., Coleman, S.J., Della Valle, G., Fryc, S., Guérin, G., Hasegawa, T., Hill, E.W., Jurka, J., Kiialainen, A., Lindgren, G., Liu, J., Magnani, E., Mickelson, J.R., Murray, J., Nergadze, S.G., Onofrio, R., Pedroni, S., Piras, M.F., Raudsepp, T., Rocchi, M., Røed, K.H., Ryder, O.A., Searle, S., Skow, L., Swinburne, J.E., Syvänen, A.C., Tozaki, T., Valberg, S.J., Vaudin, M., White, J.R., Zody, M.C., Broad Institute Genome Sequencing Platform; Broad Institute Whole Genome Assembly Team, Lander, E.S. and Lindblad-Toh, K. (2009) Genome sequence, comparative analysis, and population genetics of the domestic horse. Science 326, 865-867.
41. Ward, T.L., Valberg, S.J., Adelson, D.L., Abbey, C.A., Binns, M.M. and Mickelson, J.R. (2004) Glycogen branching enzyme (GBE1) mutation causing equine glycogen storage disease IV. Mamm. Genome 15, 570-577.
42. Xu, X. and Arnason, U. (1994) The complete mitochondrial DNA sequence of the horse, Equus caballus: Extensive heteroplasmy of the control region. Gene 148, 357-362.
43. Yoon, S.S. (2006) Glycogen storage disease: Clinical, biochemichal and molecular heterogeneity. Semin. Pediatr. Neurol. 13, 115-120.