Formulation and evaluation of topical liposomal gel for fluconazole

Indian Journal of Pharmaceutical Education and Research

Volumn 44, Issue 4, 2010, Pages 324-333

  Mitkari, B V ^a   Korde, S A ^a   Mahadik, K R ^a   Kokare, C R ^a,b  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^b Sinhgad Institute of Pharmacy   (India)

Author keywords

Factorial design; Fluconazole; Gels; Liposomes; Topical

Indexed keywords

CARBOPOL 934; CHOLESTEROL; FLUCONAZOLE; LIPOSOME; PHOSPHATIDYLCHOLINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG PENETRATION; DRUG STABILITY; FILM; FLOW KINETICS; GEL; LIPOSOMAL DELIVERY; NONHUMAN; PARTICLE SIZE; RAT; SKIN PERMEABILITY;

EID: 78249234388     PISSN: 00195464     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Schaeffer HE, Krohn DL. Liposomes in topical drug delivery. Invest. Ophthalmol. Vis. Sci. 1982;22:220-227.
2. Abdel-Mottaleb MMA, Mortada ND, Elshamy AA, Awad GAS. Preparatio and evaluation of fluconazole gels. Egypt. J. Biomed. Sci. 2007;23:266-286.
3. Mohamed MN. In vitro release of hydrophilic and hydrophobic drugs from liposomal dispersions and gels. Act. Pharm. 2006;56:311-324.
4. Kneep VM, Hinz RS, Szoka FS Jr, Guy RH. Controlled drug release from a novel liposomal delivery system I: investigation of transdermal potential. J. Control. Rel. 1988;5:211-221.
5. Schmid MH, Korting HC. Therapeutic progress with topical liposome drugs for skin Disease. Adv. Drug Del. Rev. 1996;18:335-342.
6. Glavas-Dodov M. Formulation and characterization of topical liposome gel bearing lidocaine HCl. Bull. Chem. Tech. Macedonia. 2005;24(1):59-65.
7. Singh M, Singh MP, Maiti SN, Gandhi A, Micetich RG, Atwal H. Prepartions of liposomal fluconazole and their in vitro antifungal activity. J. Microencapsul. 1993;10(2):229-236.
8. Nagarsenker MS. Preparation and evaluation of a liposomal formulation of sodium cromoglicate. Int. J. Pharm. 2003;251:49-56.
9. Sriram V, Rhodes CT. Preparat ion and chrecterization of liposomes as therapeutic delivery systems. A review. Pharm Acta Hel. 1995;70:95-111.
10. Du Plessis J, Ramchandran C, Weiner N, Muller DG. The influence of particle size of liposomes on the deposition of drug into skin. Int. J. Pharm. 1994;103:277-282.
11. Jia-You F, Yann-Lii L, Chia-Chun C, Chia-Hsuan L, Yi-Hung T. Lipid nano/submicron emulsion as vehicle for topical flurbiprofen delivery. Drug Del. 2004;11:97-105.
12. Bhatia A, Kumar R, Katare, OP. Tamoxifen in topical liposomes: development, characterization and in-vitro evaluat ion. J. Pharm. Sci. 2004;7(2):252-259.
13. Buchard W, Ross-murphy SB. Physical networks: polymers and gels. Elsevier Applied Sci. London. 1990;204-207.
14. Pavelic Z. Liposomal gel with chloramphenicol: characterization and invitro release. Act. Pharm 2004;54:319-330.
15. Bayarri S, Duran L, Costell E. Influence of sweetener on the viscoelasticity of hydrocolloids gelled systems. Food Hydrocolloids. 2004;18:611-619.
16. Calfors J, Edsman K, Petterson R. Rheological evaluation of gelrite in situ gels for ophthalmic use. Eur. J. Pharm. Sci. 1998;6:113-119.
17. Kobayashi M, Ishikawa S, Samejima M. Application of nonlinear viscoelastic analysis by the oscillation method to some pharmaceutical ointments in the Japanese Pharmacopeia. Chem. Pharm. Bull. 1982;30:4468-4478.
18. Thorgeirsdottira T, Kjoniksenb A, Kenneth DK, Kristmundsdóttira T, Nystromb B. Viscoelastic and structural properties of pharmaceutical hydrogels containing monocaprin. Eur. J. Pharm. Biopharm. 2005;59:333-342.
19. Torres LG, Iturbe R, Snowdenb MJ, Chowdhry BZ, Leharne SA. Preparation of o/w emulsions s tabi l ized by sol id par t icles and thei r characterization by oscillatory rheology. Colloid Surfac. 2007;302:439-448.
20. Tadros T. Application of rheology for assessment and prediction of thelong-term physical stability of emulsions. Adv. Colloid Interface. 2007;108-109:227-258.
21. Barry BW, Eccleston GM. Influence of gel networks in controlling consistency of o/w emulsions stabilized by mixed emulsifiers. J. Texture Stud. 1973;4:53-81.
22. Goindi S, Aggarwal N. Preparation of hydrogels of griseofulvin for dermal application. Int. J. Pharm. 2006;326:20-24.
23. Korhonen M, Hellen L, Hirvonen J, Yliruusi J. Rheological properties of creams with four different surfactant combinations-effect of storage time and conditions. Int. J. Pharm. 2001;221:187-196.
24. Lippacher A, Muller RH, Mader K. Liquid and semisolid SLNs dispersions for topical application: rheological characterization. Eur. J. Pharm. Biopharm. 2004;58:561-567.