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Volumn 62, Issue 11, 2010, Pages 3467-3476

Inactivation of the cannabinoid receptor CB1 prevents leukocyte infiltration and experimental fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CANNABINOID 1 RECEPTOR; HYDROXYPROLINE; N (4 HYDROXY 2 METHYLPHENYL)ARACHIDONAMIDE;

EID: 78249233276     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27642     Document Type: Article
Times cited : (66)

References (39)
  • 2
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: A prototypic multisystem fibrotic disorder
    • Varga J, Abraham D,. Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 2007; 117: 557 - 67.
    • (2007) J Clin Invest , vol.117 , pp. 557-67
    • Varga, J.1    Abraham, D.2
  • 3
    • 0023876160 scopus 로고
    • Identification of fibroblasts responsible for increased collagen production in localized scleroderma by in situ hybridization
    • Kahari VM, Sandberg M, Kalimo H, Vuorio T, Vuorio E,. Identification of fibroblasts responsible for increased collagen production in localized scleroderma by in situ hybridization. J Invest Dermatol 1988; 90: 664 - 70.
    • (1988) J Invest Dermatol , vol.90 , pp. 664-70
    • Kahari, V.M.1    Sandberg, M.2    Kalimo, H.3    Vuorio, T.4    Vuorio, E.5
  • 4
    • 42349116262 scopus 로고    scopus 로고
    • Cannabinoid receptors: Where they are and what they do
    • Mackie K,. Cannabinoid receptors: where they are and what they do. J Neuroendocrinol 2008; 20 Suppl 1: 10 - 4.
    • (2008) J Neuroendocrinol , vol.20 , Issue.SUPPL. 1 , pp. 10-4
    • MacKie, K.1
  • 5
    • 42349088314 scopus 로고    scopus 로고
    • Endogenous cannabinoids: Structure and metabolism
    • Bisogno T,. Endogenous cannabinoids: structure and metabolism. J Neuroendocrinol 2008; 20 Suppl 1: 1 - 9.
    • (2008) J Neuroendocrinol , vol.20 , Issue.SUPPL. 1 , pp. 1-9
    • Bisogno, T.1
  • 7
    • 38349132542 scopus 로고    scopus 로고
    • Cannabinoid receptors and the regulation of bone mass
    • Bab I, Zimmer A,. Cannabinoid receptors and the regulation of bone mass. Br J Pharmacol 2008; 153: 182 - 8.
    • (2008) Br J Pharmacol , vol.153 , pp. 182-8
    • Bab, I.1    Zimmer, A.2
  • 8
    • 18844400058 scopus 로고    scopus 로고
    • Cannabinoid-based drugs as anti-inflammatory therapeutics
    • Klein TW,. Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol 2005; 5: 400 - 11.
    • (2005) Nat Rev Immunol , vol.5 , pp. 400-11
    • Klein, T.W.1
  • 9
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI,. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990; 346: 561 - 4.
    • (1990) Nature , vol.346 , pp. 561-4
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 10
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M,. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993; 365: 61 - 5.
    • (1993) Nature , vol.365 , pp. 61-5
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 11
    • 22544439953 scopus 로고    scopus 로고
    • Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
    • Idris AI, van 't Hof RJ, Greig IR, Ridge SA, Baker D, Ross RA, et al. Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors. Nat Med 2005; 11: 774 - 9.
    • (2005) Nat Med , vol.11 , pp. 774-779
    • Idris, A.I.1    Van 'T Hof, R.J.2    Greig, I.R.3    Ridge, S.A.4    Baker, D.5    Ross, R.A.6
  • 13
    • 67651155822 scopus 로고    scopus 로고
    • Cannabinoid receptor CB1 antagonists state of the art and challenges
    • Bifulco M, Santoro A, Laezza C, Malfitano AM,. Cannabinoid receptor CB1 antagonists state of the art and challenges. Vitam Horm 2009; 81: 159 - 89.
    • (2009) Vitam Horm , vol.81 , pp. 159-89
    • Bifulco, M.1    Santoro, A.2    Laezza, C.3    Malfitano, A.M.4
  • 14
    • 61749097782 scopus 로고    scopus 로고
    • Use of cannabinoid CB1 receptor antagonists for the treatment of metabolic disorders
    • Scheen AJ, Paquot N,. Use of cannabinoid CB1 receptor antagonists for the treatment of metabolic disorders. Best Pract Res Clin Endocrinol Metab 2009; 23: 103 - 16.
    • (2009) Best Pract Res Clin Endocrinol Metab , vol.23 , pp. 103-16
    • Scheen, A.J.1    Paquot, N.2
  • 15
    • 65249092549 scopus 로고    scopus 로고
    • The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis
    • Akhmetshina A, Dees C, Busch N, Beer J, Sarter K, Zwerina J, et al. The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis. Arthritis Rheum 2009; 60: 1129 - 36.
    • (2009) Arthritis Rheum , vol.60 , pp. 1129-1136
    • Akhmetshina, A.1    Dees, C.2    Busch, N.3    Beer, J.4    Sarter, K.5    Zwerina, J.6
  • 16
    • 0036682222 scopus 로고    scopus 로고
    • The endogenous cannabinoid system controls extinction of aversive memories
    • Marsicano G, Wotjak CT, Azad SC, Bisogno T, Rammes G, Cascio MG, et al. The endogenous cannabinoid system controls extinction of aversive memories. Nature 2002; 418: 530 - 4.
    • (2002) Nature , vol.418 , pp. 530-534
    • Marsicano, G.1    Wotjak, C.T.2    Azad, S.C.3    Bisogno, T.4    Rammes, G.5    Cascio, M.G.6
  • 17
    • 33846209989 scopus 로고    scopus 로고
    • Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
    • Distler JH, Jungel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, et al. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum 2007; 56: 311 - 22.
    • (2007) Arthritis Rheum , vol.56 , pp. 311-322
    • Distler, J.H.1    Jungel, A.2    Huber, L.C.3    Schulze-Horsel, U.4    Zwerina, J.5    Gay, R.E.6
  • 18
    • 0033060910 scopus 로고    scopus 로고
    • Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1)
    • Hillard CJ, Manna S, Greenberg MJ, DiCamelli R, Ross RA, Stevenson LA, et al. Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J Pharmacol Exp Ther 1999; 289: 1427 - 33.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 1427-1433
    • Hillard, C.J.1    Manna, S.2    Greenberg, M.J.3    Dicamelli, R.4    Ross, R.A.5    Stevenson, L.A.6
  • 19
    • 33748535430 scopus 로고    scopus 로고
    • Arachidonyl-2-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model
    • Luszczki JJ, Czuczwar P, Cioczek-Czuczwar A, Czuczwar SJ,. Arachidonyl-2-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model. Eur J Pharmacol 2006; 547: 65 - 74.
    • (2006) Eur J Pharmacol , vol.547 , pp. 65-74
    • Luszczki, J.J.1    Czuczwar, P.2    Cioczek-Czuczwar, A.3    Czuczwar, S.J.4
  • 20
    • 0017250167 scopus 로고
    • Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton
    • Green MC, Sweet HO, Bunker LE,. Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton. Am J Pathol 1976; 82: 493 - 512.
    • (1976) Am J Pathol , vol.82 , pp. 493-512
    • Green, M.C.1    Sweet, H.O.2    Bunker, L.E.3
  • 21
    • 46749154199 scopus 로고    scopus 로고
    • Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis
    • Akhmetshina A, Dees C, Pileckyte M, Maurer B, Axmann R, Jungel A, et al. Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis. FASEB J 2008; 22: 2214 - 22.
    • (2008) FASEB J , vol.22 , pp. 2214-2222
    • Akhmetshina, A.1    Dees, C.2    Pileckyte, M.3    Maurer, B.4    Axmann, R.5    Jungel, A.6
  • 22
    • 33745996622 scopus 로고
    • The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid
    • Woessner JF Jr., The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 1961; 93: 440 - 7.
    • (1961) Arch Biochem Biophys , vol.93 , pp. 440-7
    • Woessner, Jr.J.F.1
  • 23
    • 74849137794 scopus 로고    scopus 로고
    • The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis
    • Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, et al. The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis. Arthritis Rheum 2010; 62: 280 - 90.
    • (2010) Arthritis Rheum , vol.62 , pp. 280-290
    • Reich, N.1    Maurer, B.2    Akhmetshina, A.3    Venalis, P.4    Dees, C.5    Zerr, P.6
  • 24
    • 40149090411 scopus 로고    scopus 로고
    • Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis
    • Skhirtladze C, Distler O, Dees C, Akhmetshina A, Busch N, Venalis P, et al. Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis. Arthritis Rheum 2008; 58: 1475 - 84.
    • (2008) Arthritis Rheum , vol.58 , pp. 1475-1484
    • Skhirtladze, C.1    Distler, O.2    Dees, C.3    Akhmetshina, A.4    Busch, N.5    Venalis, P.6
  • 25
    • 58249120518 scopus 로고    scopus 로고
    • Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis
    • Akhmetshina A, Venalis P, Dees C, Busch N, Zwerina J, Schett G, et al. Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis. Arthritis Rheum 2009; 60: 219 - 24.
    • (2009) Arthritis Rheum , vol.60 , pp. 219-224
    • Akhmetshina, A.1    Venalis, P.2    Dees, C.3    Busch, N.4    Zwerina, J.5    Schett, G.6
  • 26
    • 36448979570 scopus 로고    scopus 로고
    • Hospitalizations and mortality in systemic sclerosis: Results from the Nationwide Inpatient Sample
    • Chung L, Krishnan E, Chakravarty EF,. Hospitalizations and mortality in systemic sclerosis: results from the Nationwide Inpatient Sample. Rheumatology (Oxford) 2007; 46: 1808 - 13.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 1808-13
    • Chung, L.1    Krishnan, E.2    Chakravarty, E.F.3
  • 27
    • 33646572542 scopus 로고    scopus 로고
    • Systemic sclerosis: Hypothesis-driven treatment strategies
    • Charles C, Clements P, Furst DE,. Systemic sclerosis: hypothesis-driven treatment strategies. Lancet 2006; 367: 1683 - 91.
    • (2006) Lancet , vol.367 , pp. 1683-91
    • Charles, C.1    Clements, P.2    Furst, D.E.3
  • 28
    • 33745003240 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis
    • Teixeira-Clerc F, Julien B, Grenard P, Tran Van Nhieu J, Deveaux V, Li L, et al. CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis. Nat Med 2006; 12: 671 - 6.
    • (2006) Nat Med , vol.12 , pp. 671-676
    • Teixeira-Clerc, F.1    Julien, B.2    Grenard, P.3    Tran Van Nhieu, J.4    Deveaux, V.5    Li, L.6
  • 29
    • 51849169053 scopus 로고    scopus 로고
    • Decreased expression of caveolin 1 in patients with systemic sclerosis: Crucial role in the pathogenesis of tissue fibrosis
    • Del Galdo F, Sotgia F, de Almeida CJ, Jasmin JF, Musick M, Lisanti MP, et al. Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis. Arthritis Rheum 2008; 58: 2854 - 65.
    • (2008) Arthritis Rheum , vol.58 , pp. 2854-2865
    • Del Galdo, F.1    Sotgia, F.2    De Almeida, C.J.3    Jasmin, J.F.4    Musick, M.5    Lisanti, M.P.6
  • 30
    • 73449115656 scopus 로고    scopus 로고
    • Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis
    • Maurer B, Busch N, Jungel A, Pileckyte M, Gay RE, Michel BA, et al. Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis. Circulation 2009; 120: 2367 - 76.
    • (2009) Circulation , vol.120 , pp. 2367-2376
    • Maurer, B.1    Busch, N.2    Jungel, A.3    Pileckyte, M.4    Gay, R.E.5    Michel, B.A.6
  • 33
    • 34848886433 scopus 로고    scopus 로고
    • Therapeutic potential of cannabinoid-based drugs
    • Klein TW, Newton CA,. Therapeutic potential of cannabinoid-based drugs. Adv Exp Med Biol 2007; 601: 395 - 413.
    • (2007) Adv Exp Med Biol , vol.601 , pp. 395-413
    • Klein, T.W.1    Newton, C.A.2
  • 34
    • 58749101889 scopus 로고    scopus 로고
    • Monocyte chemoattractant proteins in the pathogenesis of systemic sclerosis
    • review
    • Distler JH, Akhmetshina A, Schett G, Distler O,. Monocyte chemoattractant proteins in the pathogenesis of systemic sclerosis. Rheumatology (Oxford) 2009; 48: 98 - 103 [review].
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 98-103
    • Distler, J.H.1    Akhmetshina, A.2    Schett, G.3    Distler, O.4
  • 35
    • 0035149215 scopus 로고    scopus 로고
    • Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: Role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis
    • Distler O, Pap T, Kowal-Bielecka O, Meyringer R, Guiducci S, Landthaler M, et al. Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis. Arthritis Rheum 2001; 44: 2665 - 78.
    • (2001) Arthritis Rheum , vol.44 , pp. 2665-2678
    • Distler, O.1    Pap, T.2    Kowal-Bielecka, O.3    Meyringer, R.4    Guiducci, S.5    Landthaler, M.6
  • 38
    • 31044456861 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells
    • Distler JH, Jungel A, Caretto D, Schulze-Horsel U, Kowal-Bielecka O, Gay RE, et al. Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells. Arthritis Rheum 2006; 54: 214 - 25.
    • (2006) Arthritis Rheum , vol.54 , pp. 214-225
    • Distler, J.H.1    Jungel, A.2    Caretto, D.3    Schulze-Horsel, U.4    Kowal-Bielecka, O.5    Gay, R.E.6
  • 39
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn TA,. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol 2004; 4: 583 - 94.
    • (2004) Nat Rev Immunol , vol.4 , pp. 583-94
    • Wynn, T.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.