Identification, isolation and characterization of a new degradation product in sultamicillin drug substance

Journal of Pharmaceutical and Biomedical Analysis

Volumn 54, Issue 3, 2011, Pages 582-587

  Kumar, Vundavilli Jagadeesh ^a   Gupta, P Badarinadh ^a   Kumar, K S R Pavan ^a   Ray, Uttam Kumar ^a   Sreenivasulu, B ^a   Kumar, G S Siva ^a   Rao, K Ranga ^a   Sharma, Hemant Kumar ^a   Mukkanti, K ^b  

^a Aurobindo Pharma Ltd   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

2D NMR; Characterization; Impurities; Stability; Sultamicillin

Indexed keywords

5 OXO 4 PHENYLIMIDAZOLIDIN 1 YL; FORMALDEHYDE; IMIDAZOLIDINE DERIVATIVE; SULTAMICILLIN; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DEGRADATION; DRUG IDENTIFICATION; DRUG IMPURITY; DRUG ISOLATION; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMPICILLIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DRUG CONTAMINATION; DRUG STABILITY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PNEUMONIA; SPECTROPHOTOMETRY, INFRARED; SULBACTAM; TANDEM MASS SPECTROMETRY;

EID: 78149499872     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.09.016     Document Type: Article

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