Tumour auto-antibody screening: Performance of protein microarrays using SEREX derived antigens

BMC Cancer

Volumn 10, Issue , 2010, Pages

  Stempfer, René ^a   Syed, Parvez ^a   Vierlinger, Klemens ^a   Pichler, Rudolf ^a   Meese, Eckart ^b   Leidinger, Petra ^b   Ludwig, Nicole ^b   Kriegner, Albert ^a   Nöhammer, Christa ^a   Weinhäusel, Andreas ^a  

^a AIT AUSTRIAN INSTITUTE OF TECHNOLOGY   (Austria)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMIDAZOLE; AUTOANTIBODY; AUTOANTIGEN; CANCER ANTIBODY; RECOMBINANT PROTEIN; TUMOR ANTIGEN; TUMOR MARKER;

ANTIBODY SCREENING; ANTIGEN DETECTION; ARTICLE; BIOMASS; BRAIN TUMOR; CONTROLLED STUDY; ESCHERICHIA COLI; HUMAN; LUNG TUMOR; MOLECULAR DYNAMICS; MOLECULAR HYBRIDIZATION; PROCESS OPTIMIZATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PROCESSING; PROTEIN PURIFICATION; REPRODUCIBILITY; SEROLOGY; TEMPERATURE; CHEMISTRY; GENETIC PROCEDURES; IMMUNOLOGY; MASS SCREENING; METABOLISM; METHODOLOGY;

ANTIBODIES, NEOPLASM; ANTIGENS, NEOPLASM; AUTOANTIBODIES; AUTOANTIGENS; BRAIN NEOPLASMS; ESCHERICHIA COLI; GENETIC TECHNIQUES; HUMANS; LUNG NEOPLASMS; MASS SCREENING; PROTEIN ARRAY ANALYSIS; RECOMBINANT PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 78149492783     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-627     Document Type: Article

References (29)

1. Committee on Developing Biomarker-Based Tools for Cancer Screening DaT Cancer Biomarkers: The Promises and Challenges of Improving Detection and Treatment 2009, The National Academic Press, Committee on Developing Biomarker-Based Tools for Cancer Screening DaT.
2. Li Y, Lee HJ, Corn RM. Detection of protein biomarkers using RNA aptamer microarrays and enzymatically amplified surface plasmon resonance imaging. Anal Chem 2007, 79:1082-1088. 10.1021/ac061849m, 2515860, 17263339.
3. Ferreira CS, Matthews CS, Missailidis S. DNA aptamers that bind to MUC1 tumour marker: design and characterization of MUC1-binding single-stranded DNA aptamers. Tumour Biol 2006, 27:289-301. 10.1159/000096085, 17033199.
4. Vicens MC, Sen A, Vanderlaan A, Drake TJ, Tan W. Investigation of molecular beacon aptamer-based bioassay for platelet-derived growth factor detection. Chembiochem 2005, 6:900-907. 10.1002/cbic.200400308, 15812865.
5. Casiano CA, Mediavilla-Varela M, Tan EM. Tumor-associated antigen arrays for the serological diagnosis of cancer. Mol Cell Proteomics 2006, 5:1745-1759. 10.1074/mcp.R600010-MCP200, 2790463, 16733262.
6. Anderson KS, LaBaer J. The sentinel within: exploiting the immune system for cancer biomarkers. J Proteome Res 2005, 4:1123-1133. 10.1021/pr0500814, 2522321, 16083262.
7. Wang X, Yu J, Sreekumar A, Varambally S, Shen R, Giacherio D, et al. Autoantibody signatures in prostate cancer. N Engl J Med 2005, 353:1224-1235. 10.1056/NEJMoa051931, 16177248.
8. Sanchez-Carbayo M. Antibody arrays: technical considerations and clinical applications in cancer. Clin Chem 2006, 52:1651-1659. 10.1373/clinchem.2005.059592, 16809399.
9. Robinson WH, Steinman L, Utz PJ. Protein arrays for autoantibody profiling and fine-specificity mapping. Proteomics 2003, 3:2077-2084. 10.1002/pmic.200300583, 14595805.
10. Gunawardana CG, Diamandis EP. High throughput proteomic strategies for identifying tumour-associated antigens. Cancer Lett 2007, 249:110-119. 10.1016/j.canlet.2007.01.002, 17306453.
11. Heubeck B, Wendler O, Bumm K, Schafer R, Muller-Vogt U, Hausler M, et al. Tumor-associated antigenic pattern in squamous cell carcinomas of the head and neck - Analysed by SEREX. Eur J Cancer 2006,
12. Tureci O, Sahin U, Zwick C, Neumann F, Pfreundschuh M. Exploitation of the antibody repertoire of cancer patients for the identification of human tumor antigens. Hybridoma 1999, 18:23-28. 10.1089/hyb.1999.18.23, 10211784.
13. Krebs P, Kurrer M, Sahin U, Tureci O, Ludewig B. Autoimmunity seen through the SEREX-scope. Autoimmun Rev 2003, 2:339-345. 10.1016/S1568-9972(03)00047-8, 14550875.
14. Zhong X, Ran YL, Lou JN, Hu D, Yu L, Zhang YS, et al. Construction of human liver cancer vascular endothelium cDNA expression library and screening of the endothelium-associated antigen genes. World J Gastroenterol 2004, 10:1402-1408.
15. Tomaino B, Cappello P, Capello M, Fredolini C, Ponzetto A, Novarino A, et al. Autoantibody signature in human ductal pancreatic adenocarcinoma. J Proteome Res 2007, 6:4025-4031. 10.1021/pr070281a, 17824682.
16. Weiner H, Faupel T, Büssow K. Protein Arrays From cDNA Expression Libraries. Protein Arrays 2004, 1-13.
17. Diesinger I, Bauer C, Brass N, Schaefers HJ, Comtesse N, Sybrecht G, et al. Toward a more complete recognition of immunoreactive antigens in squamous cell lung carcinoma. Int J Cancer 2002, 102:372-378. 10.1002/ijc.10714, 12402307.
18. Comtesse N, Zippel A, Walle S, Monz D, Backes C, Fischer U, et al. Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets. Proc Natl Acad Sci USA 2005, 102:9601-9606. 10.1073/pnas.0500404102, 1172238, 15983380.
19. Büssow K, Nordhoff E, Lubbert C, Lehrach H, Walter G. A Human cDNA Library for High-Throughput Protein Expression Screening. Genomics 2000, 65:1-8. 10.1006/geno.2000.6141, 10777659.
20. Bussow K, Cahill D, Nietfeld W, Bancroft D, Scherzinger E, Lehrach H, et al. A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library. Nucleic Acids Res 1998, 26:5007-5008. 10.1093/nar/26.21.5007, 147919, 9776767.
21. Studier FW. Protein production by auto-induction in high density shaking cultures. Protein Expr Purif 2005, 41:207-234. 10.1016/j.pep.2005.01.016, 15915565.
22. Preininger C, Bodrossy L, Sauer U, Pichler R, Weilharter A. ARChip epoxy and ARChip UV for covalent on-chip immobilization of pmoA gene-specific oligonucleotides. Anal Biochem 2004, 330:29-36. 10.1016/j.ab.2003.12.037, 15183758.
23. R Development Core Team R: A Language and Environment for Statistical Computing. 2005, R Foundation for Statistical Computing, R Development Core Team.
24. Simon R, Lam A. BRB-ArrayTools User Guide, version 3.2. Biometric Research Branch, National Cancer Institute 2009, Biometric Research Branch, National Cancer Institute., http://linus.nci.nih.gov/brb
25. Tibshirani R, Hastie T, Narasimhan B, Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci USA 2002, 99:6567-6572. 10.1073/pnas.082099299, 124443, 12011421.
26. Shoshan SH, Admon A. Novel technologies for cancer biomarker discovery: humoral proteomics. Cancer Biomark 2007, 3:141-152.
27. Fernandez MF. Autoantibodies in breast cancer sera: candidate biomarkers and reporters of tumorigenesis. Cancer Lett 2005, 230:187-198. 10.1016/j.canlet.2004.12.017, 16297705.
28. Amos MD, Bridges AJ. Standards for autoantibody testing; addressing future needs for autoimmune disease and cancer diagnosis. Cancer Biomark 2005, 1:221-227.
29. Caron M, Choquet-Kastylevsky G, Joubert-Caron R. Cancer immunomics using autoantibody signatures for biomarker discovery. Mol Cell Proteomics 2007, 6:1115-1122. 10.1074/mcp.R600016-MCP200, 17376768.