Is an involved circumferential resection margin following oesphagectomy for cancer an important prognostic indicator?

Interactive Cardiovascular and Thoracic Surgery

Volumn 11, Issue 5, 2010, Pages 645-648

  Khan, Omar A ^a   Cruttenden Wood, David ^b   Toh, Simon K ^a  

^a QUEEN ALEXANDRA HOSPITAL   (United Kingdom)

^b ROYAL BOURNEMOUTH HOSPITAL   (United Kingdom)

Author keywords

Circumferential resection margin; Oesophageal cancer

Indexed keywords

ARTICLE; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CIRCUMFERENTIAL RESECTION MARGIN; CLINICAL INDICATOR; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS CANCER; ESOPHAGUS RESECTION; EVIDENCE BASED MEDICINE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; LYMPH NODE METASTASIS; ONCOLOGICAL PARAMETERS; OUTCOME ASSESSMENT; PREDICTION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROGNOSIS; RECURRENCE RISK; STANDARDIZATION; SURGICAL APPROACH; SURVIVAL RATE; SURVIVAL TIME; TREATMENT PLANNING; TUMOR CLASSIFICATION;

BENCHMARKING; CHEMOTHERAPY, ADJUVANT; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; EVIDENCE-BASED MEDICINE; HUMANS; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; NEOPLASM, RESIDUAL; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 78149491752     PISSN: 15699293     EISSN: None     Source Type: Journal    
DOI: 10.1510/icvts.2010.236778     Document Type: Article

References (11)

1. Dunning J, Prendergast B, Mackway-Jones K. Towards evidence-based medicine in cardiothoracic surgery: best BETS. Interact CardioVasc Thorac Surg 2003;2:405-409.
2. Sagar PM, Johnston D, McMahon MJ, Dixon MF, Quirke P. Significance of circumferential resection margin involvement after oesophagectomy for cancer. Br J Surg 1993;80:1386-1388.
3. Dexter SP, Sue-Ling H, McMahon MJ, Quirke P, Mapstone N, Martin IG. Circumferential resection margin involvement: an independent predictor of survival following surgery for oesophageal cancer. Gut 2001; 48:667-670.
4. Zafirellis K, Dolan K, Fountoulakis A, Dexter SP, Martin IG, Sue-Ling HM. Multivariate analysis of clinical, operative and pathologic features of esophageal cancer: who needs adjuvant therapy? Dis Esophagus 2002; 15:155-159.
5. Khan OA, Fitzgerald JJ, Soomro I, Beggs FD, Morgan WE, Duffy JP. Prognostic significance of circumferential resection margin involvement following oesophagectomy for cancer. Br J Cancer 2003; 88:1549-1552.
6. Griffiths EA, Brummell Z, Gorthi G, Pritchard SA, Welch IM. The prognostic value of circumferential resection margin involvement in oesophageal malignancy. Eur J Surg Oncol 2006;32:413-419.
7. Sujendran V, Wheeler J, Baron R, Warren BF, Maynard N. Effect of neoadjuvant chemotherapy on circumferential margin positivity and its impact on prognosis in patients with resectable oesophageal cancer. Br J Surg 2008;95:191-194.
8. Scheepers JJ, van der Peet DL, Veenhof AA, Cuesta MA. Influence of circumferential resection margin on prognosis in distal esophageal and gastroesophageal cancer approached through the transhiatal route. Dis Esophagus 2009;22:42-48.
9. Saha AK, Sutton C, Rotimi O, Dexter S, Sue-Ling H, Sarela AI. Neoadjuvant chemotherapy and surgery for esophageal adenocarcinoma: prognostic value of circumferential resection margin and stratification of N1 category. Ann Surg Oncol 2009;16:1364-1370.
10. Hulscher JB, van Sandick JW, de Boer AG, Wijnhoven BP, Tijssen JG, Fockens P, Stalmeier PF, ten Kate FJ, van Dekken H, Obertop H, Tilanus HW, van Lanschot JJ. Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus. N Engl J Med 2002;347:1662-1669.
11. Medical Research Council Oesophageal Cancer Working Party. Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomised controlled trial. Lancet 2002;359:1727-1733