Aplastic anemia with concurrent temozolomide treatment in a patient with glioblastoma multiforme

Current Oncology

Volumn 17, Issue 4, 2010, Pages 124-126

  Oh, Jiwon ^a   Kutas, G J ^a   Davey, P ^a   Morrison, M ^a   Perry, J R ^a  

^a DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

Author keywords

Aplastic anemia; Glioblastoma multiforme; Pancytopenia; Temozolomide

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; CIPROFLOXACIN; DEXAMETHASONE; ERYTHROPOIETIN; FLUCONAZOLE; MEROPENEM; MOUTHWASH; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TEMOZOLOMIDE;

ADULT; ANAMNESIS; APHASIA; APLASTIC ANEMIA; ARTICLE; BACTERIUM DETECTION; BLADDER SURGERY; BLOOD CULTURE; BONE MARROW BIOPSY; BRAIN EDEMA; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER RECURRENCE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONFUSION; CRANIOTOMY; DRUG TOLERABILITY; DYSPHAGIA; EMERGENCY WARD; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; FEVER; FUSOBACTERIUM; GLIOBLASTOMA; HEADACHE; HEMOGLOBIN BLOOD LEVEL; HERPETIC STOMATITIS; HOSPITAL READMISSION; HUMAN; HUMAN TISSUE; HYPERTENSION; HYPOTHYROIDISM; LEUKOCYTE COUNT; MUCOSA INFLAMMATION; NEUROIMAGING; PANCYTOPENIA; SIDE EFFECT; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THRUSH; TUMOR BIOPSY; URINARY TRACT INFECTION;

EID: 78149488462     PISSN: None     EISSN: 17187729     Source Type: Journal    
DOI: 10.3747/co.v17i4.526     Document Type: Article

References (5)

1. Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-96.
2. Doyle TJ, Mikkelsen T, Croteau D, et al. Fatal hematologic toxicity with prolonged continuous administration of temozolomide (tmz) during radiation therapy (rt) in the treatment of newly-diagnosed glioblastoma multiforme (gbm): report of a phase ii trial [abstract 1546]. Proc Am Soc Clin Oncol 2005;23: [Available online at: www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=3 4&abstractID=33183; cited June 9, 2010]
3. Villano JL, Collins CA, Manasanch EE, Ramaprasad C, van Besien K. Aplastic anaemia in patient with glioblastoma multiforme treated with temozolomide. Lancet Oncol 2006;7:436-8.
4. Jalali R, Singh P, Menon H, Gujral S. Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with temozolomide. J Neurooncol 2007;85:105-7.
5. Morris EB, Kasow K, Reiss U, Ellison D, Broniscer A. Bone marrow transplantation for severe aplastic anemia secondary to temozolomide. J Neurooncol 2009;91:237-9.