LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma

Molecular Vision

Volumn 16, Issue , 2010, Pages 2236-2241

  Khan, Tanya T ^a   Li, Guorong ^a   Navarro, Iris D ^a   Kastury, Rama D ^a   Zeil, Carol J ^a   Semchyshyn, Taras M ^a   Moya, Frank J ^a   Epstein, David L ^a   Gonzalez, Pedro ^a   Challa, Pratap ^a  

^a DUKE UNIVERSITY EYE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; BRIMONIDINE; BRINZOLAMIDE; LATANOPROST; PROTEIN LYSINE 6 OXIDASE; TIMOLOL MALEATE;

ADULT; AQUEOUS HUMOR; ARTICLE; CATARACT; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FLANKING REGION; DRUG EFFECT; EXON; FEMALE; GENE EXPRESSION; GLAUCOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRAOCULAR PRESSURE; LENS CAPSULE; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOEXFOLIATION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TRABECULAR MESHWORK;

ADULT; AMINO ACID OXIDOREDUCTASES; EPITHELIAL CELLS; EXFOLIATION SYNDROME; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLAUCOMA; HUMANS; LENS CAPSULE, CRYSTALLINE; MALE; MIDDLE AGED;

EID: 78149486291     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Tarkkanen A, Kivela T, John G. Lindberg and the discovery of exfoliation syndrome. Acta Ophthalmol Scand 2002; 80:151-4.
2. Ghosh M, Speakman JS. The origin of senile lens exfoliation. Can J Ophthalmol 1983; 18:340-3.
3. Richardson TM, Epstein DL. Exfoliation glaucoma: a quantitative perfusion and ultrastructural study. Ophthalmology 1981; 88:968-80.
4. Ritch R, Schlotzer-Schrehardt U. Exfoliation syndrome. Surv Ophthalmol 2001; 45:265-315.
5. Konstas AG, Stewart WC, Stroman GA, Sine CS. Clinical presentation and initial treatment patterns in patients with exfoliation glaucoma versus primary open-angle glaucoma. Ophthalmic Surg Lasers 1997; 28:111-7.
6. Ringvold A. Epidemiology of glaucoma in northern Europe. Eur J Ophthalmol 1996; 6:26-9.
7. Jonasson F, Damji KF, Arnarsson A, Sverrisson T, Wang L, Sasaki H, Sasaki K. Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study. Eye (Lond) 2003; 17:747-53.
8. Friederich R. Eye disease in the Navajo indians. Ann Ophthalmol 1982; 14:38-40.
9. Forsius H. Prevalence of pseudoexfoliation of the lens in Finns, Lapps, Icelanders, Eskimos, and Russians. Trans Ophthalmol Soc U K 1979; 99:296-8.
10. Aström S, Linden C. Incidence and prevalence of pseudoexfoliation and open-angle glaucoma in northern Sweden: I. Baseline report. Acta Ophthalmol Scand 2007; 85:828-31.
11. Hiller R, Sperduto RD, Krueger DE. Pseudoexfoliation, intraocular pressure, and senile lens changes in a populationbased survey. Arch Ophthalmol 1982; 100:1080-2.
12. Thorleifsson G, Magnusson KP, Sulem P, Walters GB, Gudbjartsson DF, Stefansson H, Jonsson T, Jonasdottir A, Stefansdottir G, Masson G, Hardarson GA, Petursson H, Arnarsson A, Motallebipour M, Wallerman O, Wadelius C, Gulcher JR, Thorsteinsdottir U, Kong A, Jonasson F, Stefansson K. Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma. Science 2007; 317:1397-400.
13. Aragon-Martin JA, Ritch R, Liebmann J, O'Brien C, Blaaow K, Mercieca F, Spiteri A, Cobb CJ, Tarkkanen A, Rezaie T, Child AH, Sarfarazi M. Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma. Mol Vis 2008; 14:533-41.
14. Challa P, Schmidt S, Liu Y, Qin X, Vann RR, Gonzalez P, Allingham RR, Hauser MA. Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma. Mol Vis 2008; 14:146-9.
15. Fan BJ, Pasquale L, Grosskreutz CL, Rhee D, Chen T, DeAngelis MM, Kim I, del Bono E, Miller JW, Li T, Haines JL, Wiggs JL. DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinicbased population with broad ethnic diversity. BMC Med Genet 2008; 9:5.
16. Fingert JH, Alward WL, Kwon YH, Wang K, Streb LM, Sheffield VC, Stone EM. LOXL1 Mutations Are Associated with Exfoliation Syndrome in Patients from the Midwestern United States. Am J Ophthalmol 2007; 144:974-5.
17. Yang X, Zabriskie NA, Hau VS, Chen H, Tong Z, Gibbs D, Farhi P, Katz BJ, Luo L, Pearson E, Goldsmith J, Ma X, Kaminoh Y, Chen Y, Yu B, Zeng J, Zhang K, Yang Z. Genetic association of LOXL1 gene variants and exfoliation glaucoma in a Utah cohort. Cell Cycle 2008; 7:521-4.
18. Hewitt AW, Sharma S, Burdon KP, Wang JJ, Baird PN, Dimasi DP, Mackey DA, Mitchell P, Craig JE. Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people. Hum Mol Genet 2008; 17:710-6.
19. Pasutto F, Krumbiegel M, Mardin CY, Paoli D, Lammer R, Weber BH, Kruse FE, Schlotzer-Schrehardt U, Reis A. Association of LOXL1 common sequence variants in German and Italian patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci 2008; 49:1459-63.
20. Ramprasad VL, George R, Soumittra N, Sharmila F, Vijaya L, Kumaramanickavel G. Association of non-synonymous single nucleotide polymorphisms in the LOXL1 gene with pseudoexfoliation syndrome in India. Mol Vis 2008; 14:318-22.
21. Hayashi H, Gotoh N, Ueda Y, Nakanishi H, Yoshimura N. Lysyl oxidase-like 1 polymorphisms and exfoliation syndrome in the Japanese population. Am J Ophthalmol 2008; 145:582-5.
22. Mori K, Imai K, Matsuda A, Ikeda Y, Naruse S, Hitora-Takeshita H, Nakano M, Taniguchi T, Omi N, Tashiro K, Kinoshita S. LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population. Mol Vis 2008; 14:1037-40.
23. Ozaki M, Lee KY, Vithana EN, Yong VH, Thalamuthu A, Mizoguchi T, Venkatraman A, Aung T. Association of LOXL1 gene polymorphisms with pseudoexfoliation in the Japanese. Invest Ophthalmol Vis Sci 2008; 49:3976-80.
24. Fuse N, Miyazawa A, Nakazawa T, Mengkegale M, Otomo T, Nishida K. Evaluation of LOXL1 polymorphisms in eyes with exfoliation glaucoma in Japanese. Mol Vis 2008; 14:1338-43.
25. Mabuchi F, Sakurada Y, Kashiwagi K, Yamagata Z, Iijima H, Tsukahara S. Lysyl oxidase-like 1 gene polymorphisms in Japanese patients with primary open angle glaucoma and exfoliation syndrome. Mol Vis 2008; 14:1303-8.
26. Tanito M, Minami M, Akahori M, Kaidzu S, Takai Y, Ohira A, Iwata T. LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open-angle glaucoma, normal tension glaucoma, and cataract. Mol Vis 2008; 14:1898-905.
27. Lee KY, Ho SL, Thalamuthu A, Venkatraman A, Venkataraman D, Pek DC, Aung T, Vithana EN. Association of LOXL1 polymorphisms with pseudoexfoliation in the Chinese. Mol Vis 2009; 15:1120-6.
28. Chen L, Jia L, Wang N, Tang G, Zhang C, Fan S, Liu W, Meng H, Zeng W, Liu N, Wang H, Jia H. Evaluation of LOXL1 polymorphisms in exfoliation syndrome in a Chinese population. Mol Vis 2009; 15:2349-57.
29. Williams SE, Whigham BT, Liu Y, Carmichael TR, Qin X, Schmidt S, Ramsay M, Hauser MA, Allingham RR. Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population. Mol Vis 2010; 16:705-12.
30. Lucero HA, Kagan HM. Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell Mol Life Sci 2006; 63:2304-16.
31. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T. Elastic fiber homeostasis requires lysyl oxidase-like 1 protein. Nat Genet 2004; 36:178-82.
32. Zenkel M, Kruse FE, Junemann AG, Naumann GO, Schlotzer- Schrehardt U. Clusterin deficiency in eyes with pseudoexfoliation syndrome may be implicated in the aggregation and deposition of pseudoexfoliative material. Invest Ophthalmol Vis Sci 2006; 47:1982-90.
33. Zenkel M, Kruse FE, Naumann GO, Schlotzer-Schrehardt U. Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma. Invest Ophthalmol Vis Sci 2007; 48:5558-66.
34. Schlötzer-Schrehardt U, Pasutto F, Sommer P, Hornstra I, Kruse FE, Naumann GO, Reis A, Zenkel M. Genotypecorrelated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients. Am J Pathol 2008; 173:1724-35.
35. Grass GM, Lee VH. A model to predict aqueous humor and plasma pharmacokinetics of ocularly applied drugs. Invest Ophthalmol Vis Sci 1993; 34:2251-9.
36. Pascual G, Mendieta C, Mecham RP, Sommer P, Bellon JM, Bujan J. Down-regulation of lysyl oxydase-like in aging and venous insufficiency. Histol Histopathol 2008; 23:179-86.
37. Roth M, Epstein DL. Exfoliation syndrome. Am J Ophthalmol 1980; 89:477-81.