Isolation of periportal, midlobular, and centrilobular rat liver sinusoidal endothelial cells enables study of zonated drug toxicity

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 299, Issue 5, 2010, Pages

  Xie, Guanhua ^a   Wang, Lin ^a   Wang, Xiangdong ^a   Wang, Lei ^a   DeLeve, Laurie D ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Acetaminophen; CD45; Drug induced liver injury; endocytosis; Liver circulation

Indexed keywords

ALBUMIN; CD45 ANTIGEN; PARACETAMOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL POPULATION; CELL SIZE; CHRONIC GRAFT REJECTION; DRUG INDUCED DISEASE; ENDOCYTOSIS; ENDOTHELIUM CELL; FIBROSIS; FLOW CYTOMETRY; HELLP SYNDROME; IMMUNOHISTOCHEMISTRY; IMMUNOMAGNETIC SEPARATION; ISCHEMIA; LIVER INJURY; LIVER SINUSOID; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; LIVER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SPRAGUE DAWLEY RAT; TOXIC HEPATITIS;

ACETAMINOPHEN; ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD45; CELLS, CULTURED; DRUG-INDUCED LIVER INJURY; ENDOCYTOSIS; ENDOTHELIAL CELLS; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MICROSCOPY, ELECTRON, SCANNING; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78149473244     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00302.2010     Document Type: Article

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