Simple and convenient methods for the synthesis of indolo[3,2-c]acridines

Synthetic Communications

Volumn 40, Issue 23, 2010, Pages 3528-3537

  Prabakaran, Kumaresan ^a   Rajendra Prasad, Karnam Jayarampillai ^a  

^a BHARATHIAR UNIVERSITY   (India)

Author keywords

13H indolo 3,2 c acridine; 2,3,4,9 tetrahydro 1H carbazol 1 ones; 5,6 dihydro 13H indolo 3,2 c acridine 7 carboxylic acids; 7 Chloro 5,6 dihydro 13H indolo 3,2 c acridine

Indexed keywords

13H INDOLO[3,2 C]ACRIDINE; 3H INDOLO[3,2 C]ACRIDINE; 5,6 DIHYDRO 13H INDOLO[3,2 C]ACRIDINE 7 CARBOXYLIC ACID; 7 CHLORO 5,6 DIHYDRO 13H INDOLO[3,2 C]ACRIDINE; ACRIDINE DERIVATIVE; ANTHRANILIC ACID; DIPHENYL ETHER; ISATIN; SODIUM HYDROXIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL ANALYSIS; CHEMICAL REACTION; DECHLORINATION; DEHYDROGENATION; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PFITZINGER REACTION; SUBSTITUTION REACTION; SYNTHESIS;

EID: 78149462507     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910903457365     Document Type: Article

References (12)

1. Gribble, G. W. Recent developments in indole ring synthesis-methodology and applications. J. Chem. Soc., Perkin Trans. 1 2000, 1045-1075.
2. Pindur, U.; Abdoust, H. E. Indolo-2,3-quinodimethanes and stable cyclic analogs for regio- and stereocontrolled syntheses of [b]-annelated indoles. Chem. Rev. 1989, 89, 1681-1689.
3. Knolker, H-J.; Reddy, K. R. Isolation and synthesis of biologically active carbazole alkaloids. Chem. Rev. 2002, 102, 4303-4427.
4. Kirsch, G. H. Heterocyclic analogues of carbazole alkaloids. Curr. Org. Chem. 2001, 5, 507-518.
5. Katritzky, A. R.; Rachwal, S.; Rachwal, B. Recent progress in the synthesis of 1,2,3,4,-tetrahydroquinolines. Tetrahedron 1996, 52, 15031-15070.
6. Kouznetsov, V. V.; Vargas Mendez, L. Y.; Melendez Gomez, C. M. Recent progress in the synthesis of quinolines. Curr. Org. Chem. 2005, 9, 141-161.
7. Gribble, G. W. Synthetic approaches to the ellipticine alkaloids via metallation and cycloaddition chemistry. In Advances in Heterocyclic Natural Product Synthesis; W. H. Pearson (Ed.); JAI Press: Greenwich, 1990; vol. 1, p. 43.
8. Bistocchi, G. A.; Orvietani, P.; Mauffret, O.; Antri, S. E.; Deroussent, A.; Jacquignon, P. C.; Fermandjian, S.; Ricci, A.; Lescot, E. Isomeric ellipticines. Part 1. Synthesis of two linear isomers of the antitumour alkaloid ellipticine. J. Chem. Soc. Perkin Trans. 1 1992, 2935-2942.
9. Sridharan, M.; Rajendra Prasad, K. J. Novel 13H-indolo[3,2-c]acridines and their methyl derivatives. J. Chem. Res. 2007, 164-169.
10. 0-dimethoxybenzylidene)-2,3,4,9-tetrahydrocarbazol- 1-ones. J. Chem. Res. 2008, 572-577.
11. Sridharan, M.; Rajendra Prasad, K. J.; Ngendahimana, A. K.; Zeller, M. Structural investigations of novel indoloacridines. J. Chem. Crystallogr. 2009, 39, 270-278.
12. Rajendra Prasad, K. J.; Vijayalashmi, C. S. Synthesis of 4-methyl-1-oxo-tetrahydrocarba-zole. Indian J. Chem. 1994, 33B, 481.