Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits

Blood

Volumn 116, Issue 19, 2010, Pages 3809-3817

  Valeri, Valerio W ^a   Hryniewicz, Anna ^a   Andresen, Vibeke ^a   Jones, Kathy ^b   Fenizia, Claudio ^a   Bialuk, Izabela ^a   Chung, Hye Kyung ^c   Fukumoto, Risaku ^a   Parks, Robyn Washington ^a   Ferrari, Maria Grazia ^c   Nicot, Christophe ^d   Cecchinato, Valentina ^a   Ruscetti, Frank ^e   Franchini, Genoveffa ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c ADVANCED BIOSCIENCE LABORATORIES INC   (United States)

^d UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; PROTEIN P12; PROTEIN P30; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; GENOTYPE; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; MACACA; NONHUMAN; PRIORITY JOURNAL; RABBIT; RETROVIRUS INFECTION; VIRUS INFECTIVITY; VIRUS MUTANT; VIRUS REPLICATION;

EID: 78149439865     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-05-284141     Document Type: Article

References (51)

1. Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci U S A. 1980;77(12):7415-7419.
2. Gessain A, Barin F, Vernant J-C, et al. Antibodies to human T-lymphotropic virus type I in patients with tropical spastic paraparesis. Lancet. 1985;2(8452):407-410. (Pubitemid 15231248)
3. Ciminale V, Pavlakis GN, Derse D, Cunningham CP, Felber BK. Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV-I. J Virol. 1992;66(3):1737-1745.
4. Koralnik I, Gessain A, Klotman ME, Lo Monico A, Berneman ZN, Franchini G. Protein isoforms encoded by the pX region of the human T-cell leukemia/lymphotropic virus type I. Proc Natl Acad Sci U S A. 1992;89(18):8813-8817.
5. Lairmore MD, Franchini G. Human T-cell leukemia/lymphoma virus types 1 and 2. In: Knipe DM, Howley PM, editors. Fields Virology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007:2071-2106.
6. Matsuoka M. Human T-cell leukemia virus type I and adult T-cell leukemia. Oncogene. 2003;22(33):5131-5140. (Pubitemid 37059594)
7. Mesnard JM, Devaux C. Multiple control levels of cell proliferation by human T-cell leukemia virus type 1 Tax protein. Virology. 1999;257(2):277-284.
8. Johnson JM, Nicot C, Fullen J, et al. Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein. J Virol. 2001;75(13):6086-6094. (Pubitemid 32553139)
9. Koralnik IJ, Fullen J, Franchini G. The p12I, p13II, and p30II proteins encoded by human T-cell leukemia/lymphotropic virus type I open reading frames I and II are localized in three different cellular compartments. J Virol. 1993;67(4):2360-2366. (Pubitemid 23088414)
10. Ding W, Albrecht B, Luo R, et al. Endoplasmic reticulum and cis-Golgi localization of human T-lymphotropic virus type 1 p12(I): association with calreticulin and calnexin. J Virol. 2001;75(16):7672-7682. (Pubitemid 32738025)
11. Kim SJ, Nair AM, Fernandez S, Mathes L, Lairmore MD. Enhancement of LFA-1-mediated T cell adhesion by human T lymphotropic virus type 1 p12I1. J Immunol. 2006;176(9):5463-5470.
12. Banerjee P, Feuer G, Barker E. Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and reduces adherence of natural killer cells, thereby protecting HTLV-1- infected primary CD4+ T cells from autologous natural killer cell-mediated cytotoxicity despite the reduction of major histocompatibility complex class I molecules on infected cells. J Virol. 2007;81(18):9707-9717. (Pubitemid 350067675)
13. Kim SJ, Ding W, Albrecht B, Green PL, Lairmore MD. A conserved calcineurin-binding motif in human T lymphotropic virus type 1 p12I functions to modulate nuclear factor of activated T cell activation. J Biol Chem. 2003;278(18):15550-15557. (Pubitemid 36799662)
14. Ding W, Albrecht B, Kelley RE, et al. Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells. J Virol. 2002;76(20):10374-10382.
15. Mulloy JC, Crowley RW, Fullen J, Leonard WJ, Franchini G. The human T-cell leukemia/lymphotropic virus type I p12I protein binds the interleukin- 2 receptor beta and gammac chains and affects their expression on the cell surface. J Virol. 1996;70(6):3599-3605. (Pubitemid 26157340)
16. Nicot C, Mulloy JC, Ferrari MG, et al. HTLV-1 p12(I) protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells. Blood. 2001;98(3):823-829.
17. Ding W, Kim SJ, Nair AM, et al. Human T-cell lymphotropic virus type 1 p12I enhances interleukin- 2 production during T-cell activation. J Virol. 2003;77(20):11027-11039.
18. Fukumoto R, Dundr M, Nicot C, et al. Inhibition of T-cell receptor signal transduction and viral expression by the linker for activation of T cells-interacting p12I protein of human T-cell leukemia/lymphoma virus type 1. J Virol. 2007;81(17):9088-9099.
19. Fukumoto R, Andresen V, Bialuk I, et al. In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12I protein. Blood. 2009;113(16):3726-3734.
20. Nicot C, Dundr M, Johnson JM, et al. HTLV-1- encoded p30(II) is a post-transcriptional negative regulator of viral replication. Nat Med. 2004;10(2):197-201.
21. Sinha-Datta U, Datta A, Ghorbel S, Dodon MD, Nicot C. Human T-cell lymphotrophic virus type I rex and p30 interactions govern the switch between virus latency and replication. J Biol Chem. 2007;282(19):14608-14615.
22. Datta A, Silverman L, Phipps AJ, Hiraragi H, Ratner L, Lairmore MD. Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival. Retrovirology. 2007;4:49.:49.
23. Zhang W, Nisbet JW, Bartoe JT, Ding W, Lairmore MD. Human T-lymphotropic virus type 1 p30(II) functions as a transcription factor and differentially modulates CREB-responsive promoters. J Virol. 2000;74(23):11270-11277.
24. Awasthi S, Sharma A, Wong K, et al. A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions. Mol Cell Biol. 2005;25(14):6178-6198.
25. Zhang W, Nisbet JW, Albrecht B, et al. Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300. J Virol. 2001;75(20):9885-9895.
26. Taylor JM, Ghorbel S, Nicot C. Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30. BMC Genomics. 2009;10:311.
27. Arnold J, Zimmerman B, Li M, Lairmore MD, Green PL. Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation. Blood. 2008;112(9):3788-3797.
28. Zhao T, Yasunaga J, Satou Y, et al. Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB. Blood. 2009;113(12):2755-2764.
29. Landry S, Halin M, Vargas A, Lemasson I, Mesnard JM, Barbeau B. Upregulation of human T-cell leukemia virus type 1 antisense transcription by the viral tax protein. J Virol. 2009;83(4):2048-2054.
30. Saito M, Matsuzaki T, Satou Y, et al. In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology. 2009;6:19.
31. Clerc I, Polakowski N, Andre-Arpin C, et al. An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ. J Biol Chem. 2008;283(35):23903-23913.
32. Gaudray G, Gachon F, Basbous J, Biard-Piechaczyk M, Devaux C, Mesnard JM. The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription. J Virol. 2002;76(24):12813-12822.
33. Hivin P, Basbous J, Raymond F, et al. The HBZSP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies. Retrovirology. 2007;4:14.
34. Kuhlmann AS, Villaudy J, Gazzolo L, Castellazzi M, Mesnard JM, Duc DM. HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT). Retrovirology. 2007;4:92. (Pubitemid 351248157)
35. Bartoe JT, Albrecht B, Collins ND, et al. Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo. J Virol. 2000;74(3):1094-1100. (Pubitemid 30044058)
36. Derse D, Mikovits J, Ruscetti F. X-I and X-II open reading frames of HTLV-I are not required for virus replication or for immortalization of primary T-cells in vitro. Virology. 1997;237(1):123-128. (Pubitemid 27464847)
37. Silverman LR, Phipps AJ, Montgomery A, Ratner L, Lairmore MD. Human T-cell lymphotropic virus type 1 open reading frame II-encoded p30II is required for in vivo replication: evidence of in vivo reversion. J Virol. 2004;78(8):3837-3845. (Pubitemid 38437189)
38. Collins ND, Newbound GC, Albrecht B, Beard JL, Ratner L, Lairmore MD. Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood. 1998;91(12):4701-4707. (Pubitemid 28270320)
39. Arnold J, Yamamoto B, Li M, et al. Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1. Blood. 2006;107(10):3976-3982. (Pubitemid 43726804)
40. Nicot C, Astier-Gin T, Edouard E, et al. Establishment of HTLV-I-infected cell lines from French, Guianese and West Indian patients and isolation of a proviral clone producing viral particles. Virus Res. 1993;30(3):317-334. (Pubitemid 23356284)
41. Kimata JT, Wong FH, Wang JJ, Ratner L. Construction and characterization of infectious human T-cell leukemia virus type 1 molecular clones. Virology. 1994;204(2):656-664. (Pubitemid 24330871)
42. Jones KS, Petrow-Sadowski C, Huang YK, Bertolette DC, Ruscetti FW. Cell-free HTLV-1 infects dendritic cells leading to transmission and transformation of CD4(+) T cells. Nat Med. 2008; 14(4):429-436. (Pubitemid 351499395)
43. Macatonia SE, Cruickshank JK, Rudge P, Knight SC. Dendritic cells from patients with tropical spastic paraparesis are infected with HTLV-1 and stimulate autologous lymphocyte proliferation. AIDS Res Hum Retroviruses. 1992;8(9):1699-1706.
44. Allan JS, Leland M, Broussard S, Mone J, Hubbard G. Simian T-cell lymphotropic viruses (STLVs) and lymphomas in African nonhuman primates. Cancer Invest. 2001;19(4):383-395. (Pubitemid 32525186)
45. Beilke MA, Traina-Dorge V, England JD, Blanchard JL. Polymyositis, arthritis, and uveitis in a macaque experimentally infected with human T lymphotropic virus type I. Arthritis Rheum. 1996;39(4):610-615. (Pubitemid 26118038)
46. Traina-Dorge VL, Martin LN, Lorino R, Winsor EL, Beilke MA. Human T cell leukemia virus type 1 up-regulation after simian immunodeficiency virus- 1 coinfection in the nonhuman primate. J Infect Dis. 2007;195(4):562-571. (Pubitemid 46214399)
47. Lairmore MD, Silverman L, Ratner L. Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation. Oncogene. 2005;24(39):6005-6015. (Pubitemid 43086118)
48. McGinn TM, Tao B, Cartner S, et al. Association of primate T-cell lymphotropic virus infection of pig-tailed macaques with high mortality. Virology. 2002;304(2):364-378. (Pubitemid 36069176)
49. Ye J, Silverman L, Lairmore MD, Green PL. HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro. Blood. 2003;102(12):3963-3969. (Pubitemid 37486977)
50. Franchini G, Mulloy JC, Koralnik IJ, et al. The human T-cell leukemia/lymphotropic virus type I p12I protein cooperates with the E5 oncoprotein of bovine papillomavirus in cell transformation and binds the 16-kilodalton subunit of the vacuolar H+ ATPase. J Virol. 1993;67(12):7701-7704. (Pubitemid 23343909)
51. Datta A, Sinha-Datta U, Dhillon NK, Buch S, Nicot C. The HTLV-I p30 interferes with TLR4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages. J Biol Chem. 2006;281(33):23414-23424. (Pubitemid 44274116)