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Volumn 5, Issue 10, 2010, Pages

Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 1; FATTY ACID DESATURASE 2; ICOSAPENTAENOIC ACID; LEUKOTRIENE; LINOLENIC ACID; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN; UNCLASSIFIED DRUG; DELTA 5 FATTY ACID DESATURASE; DELTA-5 FATTY ACID DESATURASE; FADS2 PROTEIN, HUMAN; UNSATURATED FATTY ACID;

EID: 78149434189     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013261     Document Type: Article
Times cited : (60)

References (40)
  • 1
    • 77649083509 scopus 로고    scopus 로고
    • Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism
    • Lattka E, Illig T, Koletzko B, Heinrich J (2010) Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism. Curr Opin Lipidol; 21: 64-69.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 64-69
    • Lattka, E.1    Illig, T.2    Koletzko, B.3    Heinrich, J.4
  • 2
    • 0032929070 scopus 로고    scopus 로고
    • Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase
    • Cho HP, Nakamura MT, Clarke SD (1999) Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase. J Biol Chem; 274: 471-477.
    • (1999) J Biol Chem , vol.274 , pp. 471-477
    • Cho, H.P.1    Nakamura, M.T.2    Clarke, S.D.3
  • 3
    • 0033601177 scopus 로고    scopus 로고
    • Cloning, expression, and fatty acid regulation of the human delta-5 desaturase
    • Cho HP, Nakamura M, Clarke SD (1999) Cloning, expression, and fatty acid regulation of the human delta-5 desaturase. J Biol Chem; 274: 37335-37339.
    • (1999) J Biol Chem , vol.274 , pp. 37335-37339
    • Cho, H.P.1    Nakamura, M.2    Clarke, S.D.3
  • 4
    • 46149088018 scopus 로고    scopus 로고
    • SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease
    • Malerba G, Schaeffer L, Xumerle L, Klopp N, Trabetti E, et al. (2008) SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease. Lipids; 43: 289-299.
    • (2008) Lipids , vol.43 , pp. 289-299
    • Malerba, G.1    Schaeffer, L.2    Xumerle, L.3    Klopp, N.4    Trabetti, E.5
  • 5
    • 57349126752 scopus 로고    scopus 로고
    • Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes
    • Rzehak P, Heinrich J, Klopp N, Schaeffer L, Hoff S, et al. (2009) Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes. Br J Nutr; 101: 20-26.
    • (2009) Br J Nutr , vol.101 , pp. 20-26
    • Rzehak, P.1    Heinrich, J.2    Klopp, N.3    Schaeffer, L.4    Hoff, S.5
  • 6
    • 33744736614 scopus 로고    scopus 로고
    • Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
    • Schaeffer L, Gohlke H, Muller M, Heid IM, Palmer LJ, et al. (2006) Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet; 15: 1745-1756.
    • (2006) Hum Mol Genet , vol.15 , pp. 1745-1756
    • Schaeffer, L.1    Gohlke, H.2    Muller, M.3    Heid, I.M.4    Palmer, L.J.5
  • 7
    • 59249096217 scopus 로고    scopus 로고
    • Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
    • doi:10.1371/journal.pgen. 1000338
    • Tanaka T, Shen J, Abecasis GR, Kisialiou A, Ordovas JM, et al. (2009) Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. PLoS Genet; 5: e1000338-doi:10.1371/journal.pgen. 1000338.
    • (2009) PLoS Genet , vol.5
    • Tanaka, T.1    Shen, J.2    Abecasis, G.R.3    Kisialiou, A.4    Ordovas, J.M.5
  • 8
    • 55949102407 scopus 로고    scopus 로고
    • Genetic Variants of the FADS1 FADS2 Gene Cluster Are Associated with Altered (n-6) and (n-3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation
    • Xie L, Innis SM (2008) Genetic Variants of the FADS1 FADS2 Gene Cluster Are Associated with Altered (n-6) and (n-3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation. Journal of Nutrition; 138: 2222-2228.
    • (2008) Journal of Nutrition , vol.138 , pp. 2222-2228
    • Xie, L.1    Innis, S.M.2
  • 9
    • 18044383926 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammation
    • Calder PC (2005) Polyunsaturated fatty acids and inflammation. Biochem Soc Trans; 33: 423-427.
    • (2005) Biochem Soc Trans , vol.33 , pp. 423-427
    • Calder, P.C.1
  • 10
    • 33746830525 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
    • Calder PC (2006) n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr; 83: 1505S-1519S.
    • (2006) Am J Clin Nutr , vol.83
    • Calder, P.C.1
  • 11
    • 0035160462 scopus 로고    scopus 로고
    • Polyunsaturated n-3 fatty acids and the development of atopic disease
    • Duchen K, Bjorksten B (2001) Polyunsaturated n-3 fatty acids and the development of atopic disease. Lipids; 36: 1033-1042.
    • (2001) Lipids , vol.36 , pp. 1033-1042
    • Duchen, K.1    Bjorksten, B.2
  • 12
    • 77952849777 scopus 로고    scopus 로고
    • Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism
    • Glaser C, Heinrich J, Koletzko B (2010) Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism. Metabolism; 59: 993-999.
    • (2010) Metabolism , vol.59 , pp. 993-999
    • Glaser, C.1    Heinrich, J.2    Koletzko, B.3
  • 13
    • 70349264255 scopus 로고    scopus 로고
    • FADS gene cluster polymorphisms: Important modulators of fatty acid levels and their impact on atopic diseases
    • Lattka E, Illig T, Heinrich J, Koletzko B (2009) FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases. J Nutrigenet Nutrigenomics; 2: 119-128.
    • (2009) J Nutrigenet Nutrigenomics , vol.2 , pp. 119-128
    • Lattka, E.1    Illig, T.2    Heinrich, J.3    Koletzko, B.4
  • 15
    • 23044473710 scopus 로고    scopus 로고
    • Association of fatty acids in serum phospholipids with hay fever, specific and total immunoglobulin E
    • Kompauer I, Demmelmair H, Koletzko B, Bolte G, Linseisen J, et al. (2005) Association of fatty acids in serum phospholipids with hay fever, specific and total immunoglobulin E. Br J Nutr; 93: 529-535.
    • (2005) Br J Nutr , vol.93 , pp. 529-535
    • Kompauer, I.1    Demmelmair, H.2    Koletzko, B.3    Bolte, G.4    Linseisen, J.5
  • 16
    • 54549108771 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases
    • Calder PC (2008) Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases. Mol Nutr Food Res; 52: 885-897.
    • (2008) Mol Nutr Food Res , vol.52 , pp. 885-897
    • Calder, P.C.1
  • 18
    • 48249100909 scopus 로고    scopus 로고
    • Age at first introduction of cow milk products and other food products in relation to infant atopic manifestations in the first 2 years of life: The KOALA Birth Cohort Study
    • Snijders BE, Thijs C, van Ree R, van den Brandt PA (2008) Age at first introduction of cow milk products and other food products in relation to infant atopic manifestations in the first 2 years of life: the KOALA Birth Cohort Study. Pediatrics; 122: e115-e122.
    • (2008) Pediatrics , vol.122
    • Snijders, B.E.1    Thijs, C.2    van Ree, R.3    van den Brandt, P.A.4
  • 19
    • 18544362000 scopus 로고    scopus 로고
    • Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates
    • Heinrich J, Bolte G, Holscher B, Douwes J, Lehmann I, et al. (2002) Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates. Eur Respir J; 20: 617-623.
    • (2002) Eur Respir J , vol.20 , pp. 617-623
    • Heinrich, J.1    Bolte, G.2    Holscher, B.3    Douwes, J.4    Lehmann, I.5
  • 20
    • 33846885681 scopus 로고    scopus 로고
    • Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age
    • Sausenthaler S, Koletzko S, Schaaf B, Lehmann I, Borte M, et al. (2007) Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age. Am J Clin Nutr; 85: 530-537.
    • (2007) Am J Clin Nutr , vol.85 , pp. 530-537
    • Sausenthaler, S.1    Koletzko, S.2    Schaaf, B.3    Lehmann, I.4    Borte, M.5
  • 21
    • 0027068059 scopus 로고
    • Rapid separation of serum lipids for fatty acid analysis by a single aminopropyl column
    • Agren JJ, Julkunen A, Penttila I (1992) Rapid separation of serum lipids for fatty acid analysis by a single aminopropyl column. J Lipid Res; 33: 1871-1876.
    • (1992) J Lipid Res , vol.33 , pp. 1871-1876
    • Agren, J.J.1    Julkunen, A.2    Penttila, I.3
  • 22
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem; 226: 497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 23
    • 73149123557 scopus 로고    scopus 로고
    • High-throughput analysis of fatty acid composition of plasma glycerophospholipids
    • Glaser C, Demmelmair H, Koletzko B (2010) High-throughput analysis of fatty acid composition of plasma glycerophospholipids. J Lipid Res; 51: 216-221.
    • (2010) J Lipid Res , vol.51 , pp. 216-221
    • Glaser, C.1    Demmelmair, H.2    Koletzko, B.3
  • 24
    • 56349156089 scopus 로고    scopus 로고
    • Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: The allergenic study
    • Bottema RW, Reijmerink NE, Kerkhof M, Koppelman GH, Stelma FF, et al. (2008) Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study. Eur Respir J; 32: 593-602.
    • (2008) Eur Respir J , vol.32 , pp. 593-602
    • Bottema, R.W.1    Reijmerink, N.E.2    Kerkhof, M.3    Koppelman, G.H.4    Stelma, F.F.5
  • 25
    • 58849151877 scopus 로고    scopus 로고
    • Earlylife rotavirus and norovirus infections in relation to development of atopic manifestation in infants
    • Reimerink J, Stelma F, Rockx B, Brouwer D, Stobberingh E, et al. (2009) Earlylife rotavirus and norovirus infections in relation to development of atopic manifestation in infants. Clin Exp Allergy; 39: 254-260.
    • (2009) Clin Exp Allergy , vol.39 , pp. 254-260
    • Reimerink, J.1    Stelma, F.2    Rockx, B.3    Brouwer, D.4    Stobberingh, E.5
  • 26
    • 0019859015 scopus 로고
    • Immunoglobulin E antibodies that crossreact with vegetable foods, pollen, and Hymenoptera venom
    • Aalberse RC, Koshte V, Clemens JG (1981) Immunoglobulin E antibodies that crossreact with vegetable foods, pollen, and Hymenoptera venom. J Allergy Clin Immunol; 68: 356-364.
    • (1981) J Allergy Clin Immunol , vol.68 , pp. 356-364
    • Aalberse, R.C.1    Koshte, V.2    Clemens, J.G.3
  • 27
    • 0017646279 scopus 로고
    • Estimation of basophil-bound IgE by quantitative immunofluorescence microscopy
    • Stallman PJ, Aalberse RC (1977) Estimation of basophil-bound IgE by quantitative immunofluorescence microscopy. Int Arch Allergy Appl Immunol; 54: 9-18.
    • (1977) Int Arch Allergy Appl Immunol , vol.54 , pp. 9-18
    • Stallman, P.J.1    Aalberse, R.C.2
  • 30
    • 34247539160 scopus 로고    scopus 로고
    • Longitudinal study on cat allergen exposure and the development of allergy in young children
    • Chen CM, Rzehak P, Zutavern A, Fahlbusch B, Bischof W, et al. (2007) Longitudinal study on cat allergen exposure and the development of allergy in young children. J Allergy Clin Immunol; 119: 1148-1155.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1148-1155
    • Chen, C.M.1    Rzehak, P.2    Zutavern, A.3    Fahlbusch, B.4    Bischof, W.5
  • 31
    • 77749344604 scopus 로고    scopus 로고
    • Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life
    • Chen CM, Sausenthaler S, Bischof W, Herbarth O, Borte M, et al. (2010) Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life. Clin Exp Dermatol; 35: 238-244.
    • (2010) Clin Exp Dermatol , vol.35 , pp. 238-244
    • Chen, C.M.1    Sausenthaler, S.2    Bischof, W.3    Herbarth, O.4    Borte, M.5
  • 32
    • 8744296509 scopus 로고    scopus 로고
    • SAS Institute Inc, SAS Institute Inc., Cary, NC, USA
    • SAS Institute Inc. (2004) SAS/STAT 9.1 User's Guide SAS Institute Inc., Cary, NC, USA.
    • (2004) SAS/STAT 9.1 User's Guide
  • 33
    • 78149445589 scopus 로고    scopus 로고
    • SAS Institute Inc, SAS Institute Inc., Cary, NC, USA
    • SAS Institute Inc. (2005) SAS/Genetics 9.1.3 User's Guide SAS Institute Inc., Cary, NC, USA.
    • (2005) SAS/Genetics 9.1.3 User's Guide
  • 35
    • 77951941671 scopus 로고    scopus 로고
    • FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk
    • Molto-Puigmarti C, Plat J, Mensink RP, Muller A, Jansen E, et al. (2010) FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk. Am J Clin Nutr; 91: 1368-1376.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1368-1376
    • Molto-Puigmarti, C.1    Plat, J.2    Mensink, R.P.3    Muller, A.4    Jansen, E.5
  • 36
    • 73149094933 scopus 로고    scopus 로고
    • A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1
    • Lattka E, Eggers S, Moeller G, Heim K, Weber M, et al. (2010) A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1. J Lipid Res; 51: 182-191.
    • (2010) J Lipid Res , vol.51 , pp. 182-191
    • Lattka, E.1    Eggers, S.2    Moeller, G.3    Heim, K.4    Weber, M.5
  • 37
    • 0346463259 scopus 로고    scopus 로고
    • A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta- 6-desaturase deficiency
    • Nwankwo JO, Spector AA, Domann FE (2003) A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta- 6-desaturase deficiency. J Lipid Res; 44: 2311-2319.
    • (2003) J Lipid Res , vol.44 , pp. 2311-2319
    • Nwankwo, J.O.1    Spector, A.A.2    Domann, F.E.3
  • 38
    • 34248212154 scopus 로고    scopus 로고
    • Air pollution and development of asthma, allergy and infections in a birth cohort
    • Brauer M, Hoek G, Smit HA, de Jongste JC, Gerritsen J, et al. (2007) Air pollution and development of asthma, allergy and infections in a birth cohort. Eur Respir J; 29: 879-888.
    • (2007) Eur Respir J , vol.29 , pp. 879-888
    • Brauer, M.1    Hoek, G.2    Smit, H.A.3    de Jongste, J.C.4    Gerritsen, J.5
  • 39
    • 34548667471 scopus 로고    scopus 로고
    • Solid food introduction in relation to eczema: Results from a four-year prospective birth cohort study
    • Filipiak B, Zutavern A, Koletzko S, von Berg A, Brockow I, et al. (2007) Solid food introduction in relation to eczema: results from a four-year prospective birth cohort study. J Pediatr; 151: 352-358.
    • (2007) J Pediatr , vol.151 , pp. 352-358
    • Filipiak, B.1    Zutavern, A.2    Koletzko, S.3    von Berg, A.4    Brockow, I.5
  • 40
    • 67650549976 scopus 로고    scopus 로고
    • An alternate pathway to long-chain polyunsaturates: The FADS2 gene product {Delta}8-desaturates 20:2n-6 and 20:3n-3
    • Park WJ, Kothapalli KSD, Lawrence P, Tyburczy C, Brenna JT (2009) An alternate pathway to long-chain polyunsaturates: the FADS2 gene product {Delta}8-desaturates 20:2n-6 and 20:3n-3. J Lipid Res; 50: 1195-1202.
    • (2009) J Lipid Res , vol.50 , pp. 1195-1202
    • Park, W.J.1    Kothapalli, K.S.D.2    Lawrence, P.3    Tyburczy, C.4    Brenna, J.T.5


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