Laxative effects of agarwood on low-fiber diet-induced constipation in rats

BMC Complementary and Alternative Medicine

Volumn 10, Issue , 2010, Pages

  Kakino, Mamoru ^a   Tazawa, Shigemi ^b   Maruyama, Hiroe ^b   Tsuruma, Kazuhiro ^a   Araki, Yoko ^b   Shimazawa, Masamitsu ^a   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b Api Company Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AQUILARIA SINENSIS EXTRACT; CARMINIC ACID; LAXATIVE; PLANT EXTRACT; SENNA EXTRACT; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUILARIA SINENSIS; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DIETARY FIBER; FECES; MALE; NONHUMAN; PLANT LEAF; RAT; SENNA; SINGLE DRUG DOSE; THYMELAEACEAE; TREATMENT DURATION; WATER CONTENT; ANIMAL; CHEMISTRY; DEFECATION; DIARRHEA; DIET; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; SPRAGUE DAWLEY RAT;

ANIMALS; CARMINE; CONSTIPATION; DEFECATION; DIARRHEA; DIET; DIETARY FIBER; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FECES; LAXATIVES; MALE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, SPRAGUE-DAWLEY; SENNA PLANT; THYMELAEACEAE; WATER;

EID: 78149425693     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-10-68     Document Type: Article

References (8)

1. Mostafa SM, Bhandari S, Ritchie G, Gratton N, Wenstone R. Constipation and its implications in the critically ill patient. Br J Anaesth 2003, 91:815-819. 10.1093/bja/aeg275, 14633751.
2. Cooke WT. Laxative abuse. Acta Gastroenterol Belg 1981, 44:448-458.
3. Siegers CP, von Hertzberg-Lottin E, Otte M, Schneider B. Anthranoid laxative abuse--a risk for colorectal cancer?. Gut 1993, 34:1099-1101. 10.1136/gut.34.8.1099, 1374362, 8174962.
4. Kakino M, Izuta H, Ito T, Tsuruma K, Araki Y, Shimazawa M, Oyama M, Iinuma M, Hara H. Agarwood induces laxative effects via acetylcholine receptors on loperamide-induced constipation in mice. Biosci Biotechnol Biochem (accepted April 30, 2010).
5. Langmead L, Rampton DS. Herbal treatment in gastrointestinal and liver disease-benefits and dangers. Aliment Pharmacol Ther 2001, 15:1239-1252. 10.1046/j.1365-2036.2001.01053.x, 11552894.
6. Hara H, Ise Y, Morimoto N, Shimazawa M, Ichihashi K, Ohyama M, Iinuma M. Laxative Effect of Agarwood Leaves and Its Mechanism. Biosci Biotechnol Biochem 2008, 72:335-345. 10.1271/bbb.70361, 18256503.
7. Ng LT, Chang YS, Kadir AA. A review on agar (gaharu) producing Aquilaria species. Journal of Tropical Forest Products 1997, 2:272-285.
8. Saito T, Mizutani F, Iwanaga Y, Morikawa K, Kato H. Laxative and Anti-diarrheal Activity of Polycarbophil in Mice and Rats. Japanese Journal of Phrmacology 2002, 89:133-141.