Anthrax lethal toxin suppresses murine cardiomyocyte contractile function and intracellular Ca2+ handling via a NADPH oxidase-dependent mechanism

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Kandadi, Machender R ^a   Hua, Yinan ^a   Ma, Heng ^a   Li, Qun ^a   Kuo, Shu Ru ^b   Frankel, Arthur E ^b   Ren, Jun ^a  

^a UNIVERSITY OF WYOMING COLLEGE OF HEALTH SCIENCES   (United States)

^b SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; APOCYNIN; CALCIUM ION; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHOLAMBAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2A; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL TOXIN; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME SYNTHESIS; FETUS; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECT; FLUORESCENCE; HEART; HEART MUSCLE; METABOLISM;

BACILLUS ANTHRACIS; MURINAE;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; BLOTTING, WESTERN; CALCIUM; CELL LINE; FLUORESCENCE; HEART; MICE; MYOCARDIUM; NADPH OXIDASE;

EID: 78149420567     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013335     Document Type: Article

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