메뉴 건너뛰기




Volumn 17, Issue 12, 2010, Pages 1535-1542

Estimation of the Ischemic Penumbra Based on CT Perfusion: A Pilot Study

Author keywords

Brain; Computed tomography perfusion; Ischemic penumbra; Magnetic resonance imaging; Receiver operating characteristic curve

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ISCHEMIC PENUMBRA; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY;

EID: 78149415033     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acra.2010.08.016     Document Type: Article
Times cited : (6)

References (35)
  • 1
    • 0019822988 scopus 로고
    • Thresholds in cerebral ischemia - the ischemic penumbra
    • Astrup J., Siesjo B.K., Symon L. Thresholds in cerebral ischemia - the ischemic penumbra. Stroke 1981, 12:723-725.
    • (1981) Stroke , vol.12 , pp. 723-725
    • Astrup, J.1    Siesjo, B.K.2    Symon, L.3
  • 2
    • 0027982679 scopus 로고
    • Viability thresholds and the penumbra of focal ischemia
    • Hossmann K.A. Viability thresholds and the penumbra of focal ischemia. Ann Neurol 1994, 36:557-565.
    • (1994) Ann Neurol , vol.36 , pp. 557-565
    • Hossmann, K.A.1
  • 3
    • 0037224703 scopus 로고    scopus 로고
    • Adventures in the pathophysiology of brain ischemia: penumbra, gene expression, neuroprotection: the 2002 Thomas Willis Lecture
    • Ginsberg M.D. Adventures in the pathophysiology of brain ischemia: penumbra, gene expression, neuroprotection: the 2002 Thomas Willis Lecture. Stroke 2003, 34:214-223.
    • (2003) Stroke , vol.34 , pp. 214-223
    • Ginsberg, M.D.1
  • 4
    • 0034087002 scopus 로고    scopus 로고
    • Ametabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion reperfusion primate model
    • Frykholm P., Anderssonj L.R., Valtyssonj, et al. Ametabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion reperfusion primate model. Acta Eur Scand 2000, 102:18-26.
    • (2000) Acta Eur Scand , vol.102 , pp. 18-26
    • Frykholm, P.1    Anderssonj, L.R.2    Valtyssonj3
  • 5
    • 33847229949 scopus 로고    scopus 로고
    • Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study
    • Takasawa M., Beech J.S., Fryer T.D., et al. Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study. J Cereb Blood Flow Metab 2007, 27:679-689.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 679-689
    • Takasawa, M.1    Beech, J.S.2    Fryer, T.D.3
  • 6
    • 44449089055 scopus 로고    scopus 로고
    • Acute stroke imaging research roadmap
    • Wintermark M., Albers G.W., Alexandrov A.V., et al. Acute stroke imaging research roadmap. Stroke 2008, 39:1621-1628.
    • (2008) Stroke , vol.39 , pp. 1621-1628
    • Wintermark, M.1    Albers, G.W.2    Alexandrov, A.V.3
  • 7
    • 54349116713 scopus 로고    scopus 로고
    • Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR perfusion-weighted imaging?
    • Akazawa K., Yamada K., Matsushima S., et al. Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR perfusion-weighted imaging?. Neuroradiology 2008, 50:939-945.
    • (2008) Neuroradiology , vol.50 , pp. 939-945
    • Akazawa, K.1    Yamada, K.2    Matsushima, S.3
  • 8
    • 58149168989 scopus 로고    scopus 로고
    • Multimodal magnetic resonance imaging for assessing evolution of ischemic penumbra: a key translational medicine strategy to manage the risk of developing novel therapies for acute ischemic stroke
    • Chavez J.C., Zaleska M.M., Wang X., et al. Multimodal magnetic resonance imaging for assessing evolution of ischemic penumbra: a key translational medicine strategy to manage the risk of developing novel therapies for acute ischemic stroke. J Cerebral Blood Flow Metab 2009, 29:217-219.
    • (2009) J Cerebral Blood Flow Metab , vol.29 , pp. 217-219
    • Chavez, J.C.1    Zaleska, M.M.2    Wang, X.3
  • 9
    • 0034906401 scopus 로고    scopus 로고
    • The value of apparent diffusion coefficient maps in early cerebral ischemia
    • Desmond P.M., Lovell A.C., Rawlinson A.A., et al. The value of apparent diffusion coefficient maps in early cerebral ischemia. AJNR Am J Neuroradiol 2001, 22:1260-1267.
    • (2001) AJNR Am J Neuroradiol , vol.22 , pp. 1260-1267
    • Desmond, P.M.1    Lovell, A.C.2    Rawlinson, A.A.3
  • 10
    • 0034889456 scopus 로고    scopus 로고
    • Regional variations in the apparent diffusion coefficient and the intracellular distribution of water in rat brain during acute focal ischemia
    • Liu K.F., Li F., Tatlisumak T., et al. Regional variations in the apparent diffusion coefficient and the intracellular distribution of water in rat brain during acute focal ischemia. Stroke 2001, 32:1897-1905.
    • (2001) Stroke , vol.32 , pp. 1897-1905
    • Liu, K.F.1    Li, F.2    Tatlisumak, T.3
  • 11
    • 58149359691 scopus 로고    scopus 로고
    • Prediction of infarct growth based on apparent diffusion coefficients: penumbral assessment without intravenous contrast material
    • Rosso C., Hevia-Montiel N., Deltour S., et al. Prediction of infarct growth based on apparent diffusion coefficients: penumbral assessment without intravenous contrast material. Radiology 2009, 250:184-192.
    • (2009) Radiology , vol.250 , pp. 184-192
    • Rosso, C.1    Hevia-Montiel, N.2    Deltour, S.3
  • 12
    • 33644664472 scopus 로고    scopus 로고
    • Apparent diffusion coefficient thresholds do not predict the response to acute stroke thrombolysis
    • Loh P.S., Butcher K.S., Parsons M.W., et al. Apparent diffusion coefficient thresholds do not predict the response to acute stroke thrombolysis. Stroke 2005, 36:2626-2631.
    • (2005) Stroke , vol.36 , pp. 2626-2631
    • Loh, P.S.1    Butcher, K.S.2    Parsons, M.W.3
  • 13
    • 52449095333 scopus 로고    scopus 로고
    • The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusion
    • Lansberg M.G., Thijs V.N., Bammer R., et al. The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusion. Stroke 2008, 39:2491-2496.
    • (2008) Stroke , vol.39 , pp. 2491-2496
    • Lansberg, M.G.1    Thijs, V.N.2    Bammer, R.3
  • 14
    • 0032738040 scopus 로고    scopus 로고
    • The ischemic penumbra: operationally defined by diffusion and perfusion MRI
    • Schlaug G., Benfield A., Baird A.E., et al. The ischemic penumbra: operationally defined by diffusion and perfusion MRI. Neurology 1999, 53:1528-1537.
    • (1999) Neurology , vol.53 , pp. 1528-1537
    • Schlaug, G.1    Benfield, A.2    Baird, A.E.3
  • 15
    • 34548277932 scopus 로고    scopus 로고
    • Can the ischemic penumbra be identified on noncontrast CT of acute stroke?
    • Muir K.W., Baird-Gunning J., Walker L., et al. Can the ischemic penumbra be identified on noncontrast CT of acute stroke?. Stroke 2007, 38:2485-2490.
    • (2007) Stroke , vol.38 , pp. 2485-2490
    • Muir, K.W.1    Baird-Gunning, J.2    Walker, L.3
  • 16
    • 33947536089 scopus 로고    scopus 로고
    • Identification of the penumbra and infarct core on hyperacute noncontrast and perfusion CT
    • Parsons M.W., Pepper E.M., Bateman G.A., et al. Identification of the penumbra and infarct core on hyperacute noncontrast and perfusion CT. Neurology 2007, 68:730-736.
    • (2007) Neurology , vol.68 , pp. 730-736
    • Parsons, M.W.1    Pepper, E.M.2    Bateman, G.A.3
  • 17
    • 67449158792 scopus 로고    scopus 로고
    • Automated versus manual post-processing of perfusion-CT data in patients with acute cerebral ischemia: influence on interobserver variability
    • Soares B.P., Dankbaar J.W., Bredno J., et al. Automated versus manual post-processing of perfusion-CT data in patients with acute cerebral ischemia: influence on interobserver variability. Neuroradiology 2009, 51:445-451.
    • (2009) Neuroradiology , vol.51 , pp. 445-451
    • Soares, B.P.1    Dankbaar, J.W.2    Bredno, J.3
  • 18
    • 34447515976 scopus 로고    scopus 로고
    • Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients
    • Tan J.C., Dillon W.P., Liu S., et al. Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients. Ann Neurol 2007, 61:533-543.
    • (2007) Ann Neurol , vol.61 , pp. 533-543
    • Tan, J.C.1    Dillon, W.P.2    Liu, S.3
  • 19
    • 33645817175 scopus 로고    scopus 로고
    • Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke
    • Wintermark M., Flanders A.E., Velthuis B., et al. Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke. Stroke 2006, 37:979-985.
    • (2006) Stroke , vol.37 , pp. 979-985
    • Wintermark, M.1    Flanders, A.E.2    Velthuis, B.3
  • 20
    • 0031659826 scopus 로고    scopus 로고
    • Ischemic penumbra-the therapeutic window
    • Hakim A.M. Ischemic penumbra-the therapeutic window. Neurology 1998, 51(3 Suppl 3):S44-S46.
    • (1998) Neurology , vol.51 , Issue.3 SUPPL 3
    • Hakim, A.M.1
  • 21
    • 7644223379 scopus 로고    scopus 로고
    • Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruption
    • Warach S., Latour L.L. Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruption. Stroke 2004, 11:2659-2661.
    • (2004) Stroke , vol.11 , pp. 2659-2661
    • Warach, S.1    Latour, L.L.2
  • 22
    • 58149194564 scopus 로고    scopus 로고
    • Imaging the penumbra - strategies to detect tissue at risk after ischemic stroke
    • Ebinger M., De Silva D.A., Christensen S., et al. Imaging the penumbra - strategies to detect tissue at risk after ischemic stroke. J Clin Neurosci 2009, 16:178-187.
    • (2009) J Clin Neurosci , vol.16 , pp. 178-187
    • Ebinger, M.1    De Silva, D.A.2    Christensen, S.3
  • 23
    • 52649165720 scopus 로고    scopus 로고
    • Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
    • Hacke W., Kaste M., Bluhmki E., et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008, 359:1317-1329.
    • (2008) N Engl J Med , vol.359 , pp. 1317-1329
    • Hacke, W.1    Kaste, M.2    Bluhmki, E.3
  • 24
    • 7644241715 scopus 로고    scopus 로고
    • Evolving paradigms in neuroimaging of the ischemic penumbra
    • Kidwell C.S., Alger J.R., Saver J.L. Evolving paradigms in neuroimaging of the ischemic penumbra. Stroke 2004, 35:2662-2665.
    • (2004) Stroke , vol.35 , pp. 2662-2665
    • Kidwell, C.S.1    Alger, J.R.2    Saver, J.L.3
  • 25
    • 0032860798 scopus 로고    scopus 로고
    • Pathophysiological topography of acute ischemia by combined diffusion-weighted and perfusion MRI
    • Darby D.G., Barber P.A., Gerraty R.P., et al. Pathophysiological topography of acute ischemia by combined diffusion-weighted and perfusion MRI. Stroke 1999, 30:2043-2052.
    • (1999) Stroke , vol.30 , pp. 2043-2052
    • Darby, D.G.1    Barber, P.A.2    Gerraty, R.P.3
  • 26
    • 14344264537 scopus 로고    scopus 로고
    • Ischemia preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury
    • Moore-Olufemi S.D., Kozar R.A., Moore F.A., et al. Ischemia preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury. Shock 2005, 23:258-263.
    • (2005) Shock , vol.23 , pp. 258-263
    • Moore-Olufemi, S.D.1    Kozar, R.A.2    Moore, F.A.3
  • 27
    • 0037830807 scopus 로고    scopus 로고
    • Rapid perfusion abnormality estimation in acute stroke with temporal correlation analysis
    • Lee Y.Z., Lee J.M., Vo K., et al. Rapid perfusion abnormality estimation in acute stroke with temporal correlation analysis. Stroke 2003, 34:1686-1692.
    • (2003) Stroke , vol.34 , pp. 1686-1692
    • Lee, Y.Z.1    Lee, J.M.2    Vo, K.3
  • 28
    • 0032946781 scopus 로고    scopus 로고
    • Absent middle cerebral artery flow predicts the presence and evolution of the ischemic penumbra
    • Barber P.A., Davis S.M., Darb D.G., et al. Absent middle cerebral artery flow predicts the presence and evolution of the ischemic penumbra. Neurology 1999, 52:1125-1132.
    • (1999) Neurology , vol.52 , pp. 1125-1132
    • Barber, P.A.1    Davis, S.M.2    Darb, D.G.3
  • 29
    • 0034839778 scopus 로고    scopus 로고
    • Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient
    • Rohl L., Ostergaard L., Simonsen C.Z., et al. Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient. Stroke 2001, 32:1140-1146.
    • (2001) Stroke , vol.32 , pp. 1140-1146
    • Rohl, L.1    Ostergaard, L.2    Simonsen, C.Z.3
  • 30
    • 62649126254 scopus 로고    scopus 로고
    • Hemorrhagic transformation of ischemic stroke: prediction with CT perfusion
    • Aviv R.I., d'Esterre C.D., Murphy B.D., et al. Hemorrhagic transformation of ischemic stroke: prediction with CT perfusion. Radiology 2009, 250:867-877.
    • (2009) Radiology , vol.250 , pp. 867-877
    • Aviv, R.I.1    d'Esterre, C.D.2    Murphy, B.D.3
  • 31
    • 56849109358 scopus 로고    scopus 로고
    • CT perfusion quantification of small-vessel ischemic severity
    • Huynh T.J., Murphy B., Pettersen J.A., et al. CT perfusion quantification of small-vessel ischemic severity. AJNR Am J Neuroradiol 2008, 29:1831-1836.
    • (2008) AJNR Am J Neuroradiol , vol.29 , pp. 1831-1836
    • Huynh, T.J.1    Murphy, B.2    Pettersen, J.A.3
  • 32
    • 34248635137 scopus 로고    scopus 로고
    • Prediction of subsequent hemorrhage in acute ischemic stroke using permeability CT imaging and a distributed parameter tracer kinetic model
    • Bisdas S., Hartel M., Cheong L.H., et al. Prediction of subsequent hemorrhage in acute ischemic stroke using permeability CT imaging and a distributed parameter tracer kinetic model. J Neuroradiol 2007, 34:101-108.
    • (2007) J Neuroradiol , vol.34 , pp. 101-108
    • Bisdas, S.1    Hartel, M.2    Cheong, L.H.3
  • 33
    • 0033848141 scopus 로고    scopus 로고
    • Ischemic penumbra: evidence from functional imaging in man
    • Heiss W.D. Ischemic penumbra: evidence from functional imaging in man. J Cereb Blood Flow Metab 2000, 20:1276-1293.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1276-1293
    • Heiss, W.D.1
  • 34
    • 18744415728 scopus 로고    scopus 로고
    • Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke
    • Wintermark M., Fischbein N.J., Smith W.S., et al. Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke. AJNR Am J Neuroradiol 2005, 26:104-112.
    • (2005) AJNR Am J Neuroradiol , vol.26 , pp. 104-112
    • Wintermark, M.1    Fischbein, N.J.2    Smith, W.S.3
  • 35
    • 0037344703 scopus 로고    scopus 로고
    • Assessing tissue viability with MR diffusion and perfusion imaging
    • Schaefer P., Ozsunar Y., He J., et al. Assessing tissue viability with MR diffusion and perfusion imaging. AJNR Am J Neuroradiol 2003, 24:436-443.
    • (2003) AJNR Am J Neuroradiol , vol.24 , pp. 436-443
    • Schaefer, P.1    Ozsunar, Y.2    He, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.