Mitochondrial abnormalities in the putamen in Parkinson's disease dyskinesia

Acta Neuropathologica

Volumn 120, Issue 5, 2010, Pages 623-631

  Naydenov, Alipi V ^a   Vassoler, Fair ^a   Luksik, Andrew S ^a   Kaczmarska, Joanna ^a   Konradi, Christine ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Dyskinesia; Mitochondria; Parkinson's disease; Putamen; Respiratory chain

Indexed keywords

DOPAMINE; DOPAMINE RECEPTOR; LEVODOPA; MESSENGER RNA; MITOCHONDRIAL DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CONTROLLED STUDY; DISEASE DURATION; DOWN REGULATION; DRUG EFFECT; DRUG EXPOSURE; DYSKINESIA; FETUS; GENE EXPRESSION REGULATION; GENETIC CODE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOTHESIS; LOCOMOTION; LONG TERM EXPOSURE; MALE; METABOLITE; MICROARRAY ANALYSIS; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL ENERGY TRANSFER; NERVE CELL CULTURE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PUTAMEN; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; STRIATE CORTEX;

ANIMALS; ANTIPARKINSON AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA, MITOCHONDRIAL; DOPAMINE; DYSKINESIA, DRUG-INDUCED; HUMANS; LEVODOPA; MALE; MITOCHONDRIA; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARKINSON DISEASE; PUTAMEN; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 78149414741     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-010-0740-8     Document Type: Article

References (44)

1. JE Ahlskog MD Muenter 2001 Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature Mov Disord 16 448 458 1:STN:280:DC%2BD3MzitVCmtg%3D%3D 10.1002/mds.1090 11391738 (Pubitemid 36041148)
2. A Bender KJ Krishnan CM Morris, et al. 2006 High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease Nat Genet 38 515 517 1:CAS:528:DC%2BD28XjvVGksbs%3D 10.1038/ng1769 16604074
3. Y Benjamini Y Hochberg 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing J R Stat Soc Ser B (Methodol) 57 289 300
4. H Bernheimer W Birkmayer O Hornykiewicz K Jellinger F Seitelberger 1973 Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations J Neurol Sci 20 415 455 1:CAS:528:DyaE28XlvFSgt7k%3D 10.1016/0022-510X(73)90175-5 4272516
5. W Birkmayer O Hornykiewicz 1961 Der Dioxyphenylalanin (=DOPA)-Effekt bei der Parkinson-Akinese Wien Klin Wochenschr 73 787 788 1:STN:280: DyaF38%2FhtVKrsA%3D%3D 13869404
6. BM Bolstad RA Irizarry M Astrand TP Speed 2003 A comparison of normalization methods for high density oligonucleotide array data based on variance and bias Bioinformatics 19 185 193 1:CAS:528:DC%2BD3sXitlCnsL4%3D 10.1093/bioinformatics/19.2.185 12538238 (Pubitemid 36181903)
7. SL Budd DG Nicholls 1996 Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells J Neurochem 67 2282 2291 1:CAS:528:DyaK28Xnt1Squ70%3D 10.1046/j.1471-4159.1996.67062282.x 8931459
8. H Bueler 2009 Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease Exp Neurol 218 235 246 10.1016/j.expneurol. 2009.03.006 19303005
9. MA Cenci HS Lindgren 2007 Advances in understanding l-DOPA-induced dyskinesia Curr Opin Neurobiol 17 665 671 1:CAS:528:DC%2BD1cXjs1Kmsro%3D 10.1016/j.conb.2008.01.004 18308560 (Pubitemid 351389777)
10. LL Clay Montier JJ Deng Y Bai 2009 Number matters: control of mammalian mitochondrial DNA copy number J Genet Genomics 36 125 131 10.1016/S1673-8527(08) 60099-5 19302968
11. RL Cole C Konradi J Douglass SE Hyman 1995 Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum Neuron 14 813 823 1:CAS:528:DyaK2MXlt1aiuro%3D 10.1016/0896-6273(95)90225-2 7718243
12. Cookson MR DJ-1, PINK1, and their effects on mitochondrial pathways. Mov Disord 25(Suppl 1):S44-S48
13. M Corral-Debrinski T Horton MT Lott JM Shoffner MF Beal DC Wallace 1992 Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age Nat Genet 2 324 329 1:CAS:528:DyaK3sXnvVGntQ%3D%3D 10.1038/ng1292-324 1303288
14. G Dennis Jr BT Sherman DA Hosack, et al. 2003 DAVID: database for annotation, visualization, and integrated discovery Genome Biol 4 P3 10.1186/gb-2003-4-5-p3 12734009
15. JT Dudman ME Eaton A Rajadhyaksha, et al. 2003 Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1 J Neurochem 87 922 934 1:CAS:528:DC%2BD3sXpt1Kgsrs%3D 10.1046/j.1471-4159.2003.02067.x 14622123 (Pubitemid 37444568)
16. S Fahn D Oakes I Shoulson, et al. 2004 Levodopa and the progression of Parkinson's disease N Engl J Med 351 2498 2508 1:CAS:528:DC%2BD2cXhtVGksbnE 10.1056/NEJMoa033447 15590952 (Pubitemid 39603163)
17. PA Garris EL Ciolkowski P Pastore RM Wightman 1994 Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain J Neurosci 14 6084 6093 1:CAS:528:DyaK2cXmsVKqt7o%3D 7931564
18. CR Gerfen 2000 Molecular effects of dopamine on striatal-projection pathways Trends Neurosci 23 S64 S70 1:CAS:528:DC%2BD3cXotVGrtLs%3D 10.1016/S1471-1931(00)00019-7 11052222
19. Y Goto S Otani AA Grace 2007 The Yin and Yang of dopamine release: a new perspective Neuropharmacology 53 583 587 1:CAS:528:DC%2BD2sXhtFekurbN 10.1016/j.neuropharm.2007.07.007 17709119 (Pubitemid 47516678)
20. AA Grace BS Bunney 1984 The control of firing pattern in nigral dopamine neurons: burst firing J Neurosci 4 2877 2890 1:CAS:528:DyaL2MXhvVarsA%3D%3D 6150071
21. N Hattoria M Wanga H Taka, et al. 2009 Toxic effects of dopamine metabolism in Parkinson's disease Parkinsonism Relat Disord 15 Suppl 1 S35 S38 10.1016/S1353-8020(09)70010-0 19131041
22. DW Huang BT Sherman RA Lempicki 2009 Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat Protoc 4 44 57 1:CAS:528:DC%2BD1cXhsFCkurnI 10.1038/nprot.2008.211
23. J Jankovic 2002 Levodopa strengths and weaknesses Neurology 58 S19 S32 1:CAS:528:DC%2BD38Xit1WntbY%3D 11909982
24. P Jenner 1993 Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease Acta Neurol Scand Suppl 146 6 13 1:STN:280:DyaK3szisFelsg%3D%3D 8333254
25. P Jenner 2003 Oxidative stress in Parkinson's disease Ann Neurol 53 Suppl 3 S26 S36 1:CAS:528:DC%2BD3sXjtFGitLs%3D 10.1002/ana.10483 12666096 (discussion S36-S28) (Pubitemid 36368560)
26. A Kastner P Anglade C Bounaix, et al. 1994 Immunohistochemical study of catechol-O-methyltransferase in the human mesostriatal system Neuroscience 62 449 457 1:CAS:528:DyaK2MXhtV2ntL4%3D 10.1016/0306-4522(94)90379-4 7830891 (Pubitemid 24306669)
27. C Konradi 1998 The molecular basis of dopamine and glutamate interactions in the striatum Adv Pharmacol 42 729 733 1:CAS:528:DyaK2sXntFamurw%3D 10.1016/S1054-3589(08)60851-0 9328002
28. Y Kraytsberg E Kudryavtseva AC McKee C Geula NW Kowall K Khrapko 2006 Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons Nat Genet 38 518 520 1:CAS:528: DC%2BD28XjvVGktr0%3D 10.1038/ng1778 16604072
29. KA Laderman JR Penny F Mazzucchelli N Bresolin G Scarlato G Attardi 1996 Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from human fibroblasts transferred into mtDNA-less cells J Biol Chem 271 15891 15897 1:CAS:528:DyaK28XktFait78%3D 10.1074/jbc.271.27.15891 8663253 (Pubitemid 26236197)
30. C Li WH Wong 2001 Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection Proc Natl Acad Sci USA 98 31 36 1:CAS:528:DC%2BD3MXkslKnuw%3D%3D 10.1073/pnas.011404098 11134512 (Pubitemid 32095858)
31. KA Maguire-Zeiss DW Short HJ Federoff 2005 Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease? Brain Res Mol Brain Res 134 18 23 1:CAS:528:DC%2BD2MXisFGmurY%3D 10.1016/j.molbrainres.2004.09.014 15790526 (Pubitemid 40409494)
32. KS McNaught CW Olanow B Halliwell O Isacson P Jenner 2001 Failure of the ubiquitin-proteasome system in Parkinson's disease Nat Rev Neurosci 2 589 594 1:CAS:528:DC%2BD3MXmtVaqtbc%3D 10.1038/35086067 11484002 (Pubitemid 33679832)
33. WJ Nicklas M Saporito A Basma HM Geller RE Heikkila 1992 Mitochondrial mechanisms of neurotoxicity Ann N Y Acad Sci 648 28 36 1:CAS:528: DyaK38XlvVKju78%3D 10.1111/j.1749-6632.1992.tb24521.x 1637057
34. N Pankratz T Foroud 2007 Genetics of Parkinson disease Genet Med 9 801 811 10.1097/GIM.0b013e31815bf97c 18091429 (Pubitemid 350295207)
35. S Prithivirajsingh MD Story SA Bergh, et al. 2004 Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation FEBS Lett 571 227 232 1:CAS:528:DC%2BD2cXmtVWjtbg%3D 10.1016/j.febslet.2004.06.078 15280047 (Pubitemid 38992952)
36. A Rajadhyaksha A Barczak W Macias JC Leveque SE Lewis C Konradi 1999 l-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons J Neurosci 19 6348 6359 1:CAS:528:DyaK1MXkslCqsb4%3D 10414964
37. ME Rice SJ Cragg 2008 Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway Brain Res Rev 58 303 313 1:CAS:528:DC%2BD1cXhtVagt7vI 10.1016/j.brainresrev.2008.02.004 18433875
38. EK Richfield JB Penney AB Young 1989 Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system Neuroscience 30 767 777 1:CAS:528:DyaL1MXltV2nu7s%3D 10.1016/0306- 4522(89)90168-1 2528080 (Pubitemid 19197155)
39. S Rozen H Skaletsky 2000 Primer3 on the WWW for general users and for biologist programmers Methods Mol Biol 132 365 386 1:CAS:528:DyaK1MXmslKqsbo%3D 10547847
40. AH Schapira 2008 Mitochondria in the aetiology and pathogenesis of Parkinson's disease Lancet Neurol 7 97 109 1:CAS:528:DC%2BD1cXhtlaqtbg%3D 10.1016/S1474-4422(07)70327-7 18093566 (Pubitemid 350251942)
41. AH Schapira A Hartley MW Cleeter JM Cooper 1993 Free radicals and mitochondrial dysfunction in Parkinson's disease Biochem Soc Trans 21 367 370 1:CAS:528:DyaK3sXkt1GmtLs%3D 8359498
42. AH Schapira CW Olanow 2008 Drug selection and timing of initiation of treatment in early Parkinson's disease Ann Neurol 64 Suppl 2 S47 S55 1:CAS:528:DC%2BD1MXhsFKjs74%3D 19127579
43. JL Yang L Weissman VA Bohr MP Mattson 2008 Mitochondrial DNA damage and repair in neurodegenerative disorders DNA Repair (Amst) 7 1110 1120 1:CAS:528:DC%2BD1cXnt1aktro%3D 10.1016/j.dnarep.2008.03.012
44. GD Zeevalk LP Bernard C Song M Gluck J Ehrhart 2005 Mitochondrial inhibition and oxidative stress: reciprocating players in neurodegeneration Antioxid Redox Signal 7 1117 1139 1:CAS:528:DC%2BD2MXos1eqsL8%3D 10.1089/ars.2005.7.1117 16115016 (Pubitemid 41232508)