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Volumn 249, Issue 3, 2010, Pages 224-230

Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: Implications for cancer prevention

Author keywords

32P Postlabeling assay; Apoptosis; Benzo(a)pyrene; DNA adducts; DNA repair; HepG2

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; CYTOCHROME P450 1A1; DIMETHYL SULFOXIDE; RETINOIC ACID;

EID: 78149412193     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.09.019     Document Type: Article
Times cited : (26)

References (63)
  • 1
    • 26444518150 scopus 로고    scopus 로고
    • Apoptotic events induced by naturally occurring retinoids ATRA and 13-cis retinoic acid on human hepatoma cell lines Hep3B and HepG2
    • Arce F., Gatjens-Boniche O., Vargas E., Valverde B., Diaz C. Apoptotic events induced by naturally occurring retinoids ATRA and 13-cis retinoic acid on human hepatoma cell lines Hep3B and HepG2. Cancer Lett. 2005, 229:271-281.
    • (2005) Cancer Lett. , vol.229 , pp. 271-281
    • Arce, F.1    Gatjens-Boniche, O.2    Vargas, E.3    Valverde, B.4    Diaz, C.5
  • 3
    • 0031903666 scopus 로고    scopus 로고
    • Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro
    • Braithwaite E., Wu X., Wang Z. Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro. Carcinogenesis 1998, 19:1239-1246.
    • (1998) Carcinogenesis , vol.19 , pp. 1239-1246
    • Braithwaite, E.1    Wu, X.2    Wang, Z.3
  • 4
    • 0031976795 scopus 로고    scopus 로고
    • Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation
    • Chang W.L., Chapkin R.S., Lupton J.R. Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation. J. Nutr. 1998, 128:491-497.
    • (1998) J. Nutr. , vol.128 , pp. 491-497
    • Chang, W.L.1    Chapkin, R.S.2    Lupton, J.R.3
  • 6
    • 70449640536 scopus 로고    scopus 로고
    • Natural products for chemopreventive and adjunctive therapy in oncologic disease
    • Dennis T., Fanous M., Mousa S. Natural products for chemopreventive and adjunctive therapy in oncologic disease. Nutr. Cancer 2009, 61:587-597.
    • (2009) Nutr. Cancer , vol.61 , pp. 587-597
    • Dennis, T.1    Fanous, M.2    Mousa, S.3
  • 9
    • 0028789425 scopus 로고
    • The killer and the executioner: how apoptosis controls malignancy
    • Green D.R., Martin S.J. The killer and the executioner: how apoptosis controls malignancy. Curr. Opin. Immunol. 1995, 7:694-703.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 694-703
    • Green, D.R.1    Martin, S.J.2
  • 10
    • 59649094883 scopus 로고    scopus 로고
    • Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA
    • Guggenheim E.R., Xu D., Zhang C.X., Chang P.V., Lippard S.J. Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Chembiochem 2009, 10:141-157.
    • (2009) Chembiochem , vol.10 , pp. 141-157
    • Guggenheim, E.R.1    Xu, D.2    Zhang, C.X.3    Chang, P.V.4    Lippard, S.J.5
  • 11
    • 0000530035 scopus 로고
    • Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo
    • Gupta R.C. Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc. Natl Acad. Sci. USA 1984, 81:6943-6947.
    • (1984) Proc. Natl Acad. Sci. USA , vol.81 , pp. 6943-6947
    • Gupta, R.C.1
  • 12
    • 8844260373 scopus 로고    scopus 로고
    • Repair of exocyclic DNA adducts: rings of complexity
    • Hang B. Repair of exocyclic DNA adducts: rings of complexity. Bioessays 2004, 26:1195-1208.
    • (2004) Bioessays , vol.26 , pp. 1195-1208
    • Hang, B.1
  • 13
    • 0142228320 scopus 로고    scopus 로고
    • Tobacco carcinogens, their biomarkers and tobacco-induced cancer
    • Hecht S.S. Tobacco carcinogens, their biomarkers and tobacco-induced cancer. Nat. Rev. 2003, 3:733-744.
    • (2003) Nat. Rev. , vol.3 , pp. 733-744
    • Hecht, S.S.1
  • 18
    • 78149414864 scopus 로고    scopus 로고
    • Oncogenes, tumor suppress genes, and mutations in cancer cells
    • Oxford University Press, New York
    • Josephy P., Mannervik B. Oncogenes, tumor suppress genes, and mutations in cancer cells. Molecular Toxicology 2006, 155-190. Oxford University Press, New York. Second edition.
    • (2006) Molecular Toxicology , pp. 155-190
    • Josephy, P.1    Mannervik, B.2
  • 20
    • 0037211539 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo
    • Kondraganti S.R., Fernandez-Salguero P., Gonzalez F.J., Ramos K.S., Jiang W., Moorthy B. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo. Int. J. Cancer 2003, 103:5-11.
    • (2003) Int. J. Cancer , vol.103 , pp. 5-11
    • Kondraganti, S.R.1    Fernandez-Salguero, P.2    Gonzalez, F.J.3    Ramos, K.S.4    Jiang, W.5    Moorthy, B.6
  • 21
    • 0038060729 scopus 로고    scopus 로고
    • 2,2μ,4,6,6μ-Pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB
    • Lee Y.W., Park H.J., Son K.W., Hennig B., Robertson L.W., Toborek M. 2,2μ,4,6,6μ-Pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicol. Appl. Pharmacol. 2003, 189:1-10.
    • (2003) Toxicol. Appl. Pharmacol. , vol.189 , pp. 1-10
    • Lee, Y.W.1    Park, H.J.2    Son, K.W.3    Hennig, B.4    Robertson, L.W.5    Toborek, M.6
  • 22
    • 67650496219 scopus 로고    scopus 로고
    • Cancer prevention: from 1727 to milestones of the past 100years
    • Lippman S.M., Hawk E.T. Cancer prevention: from 1727 to milestones of the past 100years. Cancer Res. 2009, 69:5269-5284.
    • (2009) Cancer Res. , vol.69 , pp. 5269-5284
    • Lippman, S.M.1    Hawk, E.T.2
  • 24
    • 0030569259 scopus 로고    scopus 로고
    • Monophosphate 32P-postlabeling assay of DNA adducts from 1,2:3,4-diepoxybutane, the most genotoxic metabolite of 1,3-butadiene: in vitro methodological studies and in vivo dosimetry
    • Mabon N., Moorthy B., Randerath E., Randerath K. Monophosphate 32P-postlabeling assay of DNA adducts from 1,2:3,4-diepoxybutane, the most genotoxic metabolite of 1,3-butadiene: in vitro methodological studies and in vivo dosimetry. Mutat. Res. 1996, 371:87-104.
    • (1996) Mutat. Res. , vol.371 , pp. 87-104
    • Mabon, N.1    Moorthy, B.2    Randerath, E.3    Randerath, K.4
  • 26
    • 0031731989 scopus 로고    scopus 로고
    • Genetics of programmed cell death in C. elegans: past, present and future
    • Metzstein M.M., Stanfield G.M., Horvitz H.R. Genetics of programmed cell death in C. elegans: past, present and future. Trends Genet. 1998, 14:410-416.
    • (1998) Trends Genet. , vol.14 , pp. 410-416
    • Metzstein, M.M.1    Stanfield, G.M.2    Horvitz, H.R.3
  • 28
    • 0033931962 scopus 로고    scopus 로고
    • Persistent expression of 3-methylcholanthrene-inducible cytochromes P4501A in rat hepatic and extrahepatic tissues
    • Moorthy B. Persistent expression of 3-methylcholanthrene-inducible cytochromes P4501A in rat hepatic and extrahepatic tissues. J. Pharmacol. Exp. Ther. 2000, 294:313-322.
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 313-322
    • Moorthy, B.1
  • 29
    • 0029821024 scopus 로고    scopus 로고
    • Pentachlorophenol enhances 9-hydroxybenzo [a] pyrene-induced hepatic DNA adduct formation in vivo and inhibits microsomal epoxide hydrolase and glutathione S-transferase activities in vitro: likely inhibition of epoxide detoxication by pentachlorophenol
    • Moorthy B., Randerath K. Pentachlorophenol enhances 9-hydroxybenzo [a] pyrene-induced hepatic DNA adduct formation in vivo and inhibits microsomal epoxide hydrolase and glutathione S-transferase activities in vitro: likely inhibition of epoxide detoxication by pentachlorophenol. Arch. Toxicol. 1996, 70:696-703.
    • (1996) Arch. Toxicol. , vol.70 , pp. 696-703
    • Moorthy, B.1    Randerath, K.2
  • 30
    • 4644313273 scopus 로고    scopus 로고
    • Retinoic acid increases the expression of p53 and proapoptotic caspases and sensitizes keratinocytes to apoptosis: a possible explanation for tumor preventive action of retinoids
    • Mrass P., Rendl M., Mildner M., Gruber F., Lengauer B., Ballaun C., Eckhart L., Tschachler E. Retinoic acid increases the expression of p53 and proapoptotic caspases and sensitizes keratinocytes to apoptosis: a possible explanation for tumor preventive action of retinoids. Cancer Res. 2004, 64:6542-6548.
    • (2004) Cancer Res. , vol.64 , pp. 6542-6548
    • Mrass, P.1    Rendl, M.2    Mildner, M.3    Gruber, F.4    Lengauer, B.5    Ballaun, C.6    Eckhart, L.7    Tschachler, E.8
  • 31
    • 0025832194 scopus 로고
    • Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens
    • Natarajan A.T., Darroudi F. Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens. Mutagenesis 1991, 6:399-403.
    • (1991) Mutagenesis , vol.6 , pp. 399-403
    • Natarajan, A.T.1    Darroudi, F.2
  • 32
    • 77955590506 scopus 로고    scopus 로고
    • Between death and survival: retinoic acid in regulation of apoptosis
    • Noy N. Between death and survival: retinoic acid in regulation of apoptosis. Annu. Rev. Nutr. 2010, 30:201-217.
    • (2010) Annu. Rev. Nutr. , vol.30 , pp. 201-217
    • Noy, N.1
  • 33
    • 0000889408 scopus 로고    scopus 로고
    • Carsarett and Doull's Toxicology: The Basic Science of Poisons
    • C.D. Klaassen (Ed.)
    • Parkinson A. Carsarett and Doull's Toxicology: The Basic Science of Poisons. Biotransformation of xenobiotics 2001, 133. C.D. Klaassen (Ed.).
    • (2001) Biotransformation of xenobiotics , pp. 133
    • Parkinson, A.1
  • 34
    • 78149412896 scopus 로고    scopus 로고
    • The relationships between levels of DNA adducts and tumor incidence in different tissues of B6C3F1 male mice treated with benzo(a)pyrene and a reconstituted PAH mixture (unpublished data).
    • Phillips, T. D., Smith, M.R., Zhou, G.D., Donnelly, K.C. The relationships between levels of DNA adducts and tumor incidence in different tissues of B6C3F1 male mice treated with benzo(a)pyrene and a reconstituted PAH mixture (unpublished data).
    • Phillips, T.D.1    Smith, M.R.2    Zhou, G.D.3    Donnelly, K.C.4
  • 35
    • 0022930309 scopus 로고
    • Comparative 32P-analysis of cigarette smoke-induced DNA damage in human tissues and mouse skin
    • Randerath E., Avitts T.A., Reddy M.V., Miller R.H., Everson R.B., Randerath K. Comparative 32P-analysis of cigarette smoke-induced DNA damage in human tissues and mouse skin. Cancer Res. 1986, 46:5869-5877.
    • (1986) Cancer Res. , vol.46 , pp. 5869-5877
    • Randerath, E.1    Avitts, T.A.2    Reddy, M.V.3    Miller, R.H.4    Everson, R.B.5    Randerath, K.6
  • 37
    • 0029829295 scopus 로고    scopus 로고
    • DNA damage induced in mouse tissues by organic wood preserving waste extracts as assayed by 32P-postlabeling
    • Randerath E., Zhou G.D., Donnelly K.C., Safe S.H., Randerath K. DNA damage induced in mouse tissues by organic wood preserving waste extracts as assayed by 32P-postlabeling. Arch. Toxicol. 1996, 70:683-695.
    • (1996) Arch. Toxicol. , vol.70 , pp. 683-695
    • Randerath, E.1    Zhou, G.D.2    Donnelly, K.C.3    Safe, S.H.4    Randerath, K.5
  • 38
    • 0031114760 scopus 로고    scopus 로고
    • Organ-specific oxidative DNA damage associated with normal birth in rats
    • Randerath E., Zhou G.D., Randerath K. Organ-specific oxidative DNA damage associated with normal birth in rats. Carcinogenesis 1997, 18:859-866.
    • (1997) Carcinogenesis , vol.18 , pp. 859-866
    • Randerath, E.1    Zhou, G.D.2    Randerath, K.3
  • 41
    • 0030612412 scopus 로고    scopus 로고
    • Comparative 32P-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals
    • Randerath K., Zhou G.D., Randerath E., Safe S.H., Donnelly K.C. Comparative 32P-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals. Environ. Mol. Mutagen. 1997, 29:372-378.
    • (1997) Environ. Mol. Mutagen. , vol.29 , pp. 372-378
    • Randerath, K.1    Zhou, G.D.2    Randerath, E.3    Safe, S.H.4    Donnelly, K.C.5
  • 43
    • 0022774562 scopus 로고
    • Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts
    • Reddy M.V., Randerath K. Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis 1986, 7:1543-1551.
    • (1986) Carcinogenesis , vol.7 , pp. 1543-1551
    • Reddy, M.V.1    Randerath, K.2
  • 44
    • 33747884339 scopus 로고    scopus 로고
    • DNA damage-induced cell death by apoptosis
    • Roos W.P., Kaina B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 2006, 12:440-450.
    • (2006) Trends Mol. Med. , vol.12 , pp. 440-450
    • Roos, W.P.1    Kaina, B.2
  • 45
    • 5344243725 scopus 로고    scopus 로고
    • Polychlorinated biphenyl mixtures (Aroclors) induce apoptosis via Bcl-2, Bax and caspase-3 proteins in neuronal cell cultures
    • Sanchez-Alonso J.A., Lopez-Aparicio P., Recio M.N., Perez-Albarsanz M.A. Polychlorinated biphenyl mixtures (Aroclors) induce apoptosis via Bcl-2, Bax and caspase-3 proteins in neuronal cell cultures. Toxicol. Lett. 2004, 153:311-326.
    • (2004) Toxicol. Lett. , vol.153 , pp. 311-326
    • Sanchez-Alonso, J.A.1    Lopez-Aparicio, P.2    Recio, M.N.3    Perez-Albarsanz, M.A.4
  • 47
    • 0036255163 scopus 로고    scopus 로고
    • Genetic susceptibility-molecular epidemiology of head and neck cancer
    • Sturgis E.M., Wei Q. Genetic susceptibility-molecular epidemiology of head and neck cancer. Curr. Opin. Oncol. 2002, 14:310-317.
    • (2002) Curr. Opin. Oncol. , vol.14 , pp. 310-317
    • Sturgis, E.M.1    Wei, Q.2
  • 48
    • 0037089487 scopus 로고    scopus 로고
    • The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells
    • Sun S.Y., Yue P., Chen X., Hong W.K., Lotan R. The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells. Cancer Res. 2002, 62:2430-2436.
    • (2002) Cancer Res. , vol.62 , pp. 2430-2436
    • Sun, S.Y.1    Yue, P.2    Chen, X.3    Hong, W.K.4    Lotan, R.5
  • 50
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science (New York, N. Y.) 1995, 267:1456-1462.
    • (1995) Science (New York, N. Y.) , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 52
    • 0004104069 scopus 로고    scopus 로고
    • US EPA, Environmental Protection Agency, Washington, DC
    • EPA Integrated Risk Information System (IRIS) 2003, US EPA, Environmental Protection Agency, Washington, DC.
    • (2003) EPA Integrated Risk Information System (IRIS)
  • 53
    • 2142695286 scopus 로고    scopus 로고
    • Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation
    • Uno S., Dalton T.P., Derkenne S., Curran C.P., Miller M.L., Shertzer H.G., Nebert D.W. Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation. Mol. Pharmacol. 2004, 65:1225-1237.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 1225-1237
    • Uno, S.1    Dalton, T.P.2    Derkenne, S.3    Curran, C.P.4    Miller, M.L.5    Shertzer, H.G.6    Nebert, D.W.7
  • 54
    • 33645105462 scopus 로고    scopus 로고
    • Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate
    • Uno S., Dalton T.P., Dragin N., Curran C.P., Derkenne S., Miller M.L., Shertzer H.G., Gonzalez F.J., Nebert D.W. Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate. Mol. Pharmacol. 2006, 69:1103-1114.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1103-1114
    • Uno, S.1    Dalton, T.P.2    Dragin, N.3    Curran, C.P.4    Derkenne, S.5    Miller, M.L.6    Shertzer, H.G.7    Gonzalez, F.J.8    Nebert, D.W.9
  • 57
    • 0030068922 scopus 로고    scopus 로고
    • Evolutionary conservation of a genetic pathway of programmed cell death
    • Yuan J. Evolutionary conservation of a genetic pathway of programmed cell death. J. Cell. Biochem. 1996, 60:4-11.
    • (1996) J. Cell. Biochem. , vol.60 , pp. 4-11
    • Yuan, J.1
  • 59
    • 0034646139 scopus 로고    scopus 로고
    • Effects of different diets and dietary restriction on perinatal endogenous DNA adducts. Time dependence of oxidative and presumptive nonoxidative lesions
    • Zhou G., Hernandez N.S., Randerath E., Randerath K. Effects of different diets and dietary restriction on perinatal endogenous DNA adducts. Time dependence of oxidative and presumptive nonoxidative lesions. Mutat. Res. 2000, 447:137-147.
    • (2000) Mutat. Res. , vol.447 , pp. 137-147
    • Zhou, G.1    Hernandez, N.S.2    Randerath, E.3    Randerath, K.4
  • 60
    • 0032806448 scopus 로고    scopus 로고
    • Acute elevation by short-term dietary restriction or food deprivation of type I I-compound levels in rat liver DNA
    • Zhou G.D., Hernandez N.S., Randerath E., Randerath K. Acute elevation by short-term dietary restriction or food deprivation of type I I-compound levels in rat liver DNA. Nutr. Cancer 1999, 35:87-95.
    • (1999) Nutr. Cancer , vol.35 , pp. 87-95
    • Zhou, G.D.1    Hernandez, N.S.2    Randerath, E.3    Randerath, K.4
  • 61
    • 37349063396 scopus 로고    scopus 로고
    • DNA adducts from alkoxyallylbenzene herb and spice constituents in cultured human (HepG2) cells
    • Zhou G.D., Moorthy B., Bi J., Donnelly K.C., Randerath K. DNA adducts from alkoxyallylbenzene herb and spice constituents in cultured human (HepG2) cells. Environ. Mol. Mutagen. 2007, 48:715-721.
    • (2007) Environ. Mol. Mutagen. , vol.48 , pp. 715-721
    • Zhou, G.D.1    Moorthy, B.2    Bi, J.3    Donnelly, K.C.4    Randerath, K.5
  • 62
    • 0035828184 scopus 로고    scopus 로고
    • Effects of dietary transition metals on oxidative DNA lesions in neonatal rats
    • Zhou G.D., Randerath E., Randerath K. Effects of dietary transition metals on oxidative DNA lesions in neonatal rats. Mutat. Res. 2001, 479:71-79.
    • (2001) Mutat. Res. , vol.479 , pp. 71-79
    • Zhou, G.D.1    Randerath, E.2    Randerath, K.3
  • 63
    • 7244240598 scopus 로고    scopus 로고
    • Effects of NQO1 deficiency on levels of cyclopurines and other oxidative DNA lesions in liver and kidney of young mice
    • Zhou G.D., Randerath K., Donnelly K.C., Jaiswal A.K. Effects of NQO1 deficiency on levels of cyclopurines and other oxidative DNA lesions in liver and kidney of young mice. Int. J. Cancer 2004, 112:877-883.
    • (2004) Int. J. Cancer , vol.112 , pp. 877-883
    • Zhou, G.D.1    Randerath, K.2    Donnelly, K.C.3    Jaiswal, A.K.4


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