Methylation patterns of genes coding for drug-metabolizing enzymes in tamoxifen-resistant breast cancer tissues

Journal of Molecular Medicine

Volumn 88, Issue 11, 2010, Pages 1123-1131

  Kim, Sun Jung ^a   Kang, Han Sung ^b   Jung, So Youn ^b   Min, Sun Young ^b   Lee, Seeyoun ^b   Kim, Seok Won ^b   Kwon, Youngmee ^b   Lee, Keun Seok ^b   Shin, Kyung Hwan ^b   Ro, Jungsil ^b  

^a Dongguk University   (South Korea)

^b National Cancer Center   (South Korea)

Author keywords

Drug metabolizing enzymes; Methylation; Tamoxifen resistance

Indexed keywords

BISULFITE; CATECHOL METHYLTRANSFERASE; CYCLIN D1; CYTOCHROME P450 1A1; CYTOCHROME P450 2D6; DRUG METABOLIZING ENZYME; KI 67 ANTIGEN; MESSENGER RNA; RNA; SULFOTRANSFERASE 1A1; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NAT1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER CONTROL; CANCER TISSUE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENOME; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STAINING;

ADULT; AGED; ANTINEOPLASTIC AGENTS, HORMONAL; ARYLAMINE N-ACETYLTRANSFERASE; ARYLSULFOTRANSFERASE; BREAST NEOPLASMS; CATECHOL O-METHYLTRANSFERASE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2D6; DNA METHYLATION; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; ISOENZYMES; MIDDLE AGED; SEQUENCE ANALYSIS, DNA; TAMOXIFEN; TUMOR MARKERS, BIOLOGICAL;

EID: 78149406498     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-010-0652-z     Document Type: Article

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