Study of the morphological patterns and association of Epstein-Barr virus and human herpes virus 8 in acquired immunodeficiency deficiency syndrome-related reactive lymphadenopathy

Indian Journal of Pathology and Microbiology

Volumn 53, Issue 4, 2010, Pages 723-728

  Gujral, S ^a   Gandhi, J S ^a   Valsangkar, S ^a   Shet, T M ^a   Epari, S ^a   Subramanian, P G ^a  

^a TATA MEMORIAL HOSPITAL   (India)

Author keywords

AIDS; EBV; lymphadenopathy

Indexed keywords

LATENCY ASSOCIATED NUCLEAR ANTIGEN; RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; ARTICLE; CD8+ T LYMPHOCYTE; CHILD; CLINICAL ARTICLE; EPSTEIN BARR VIRUS; FEMALE; GERMINAL CENTER; HUMAN; HUMAN HERPESVIRUS 8; IMMUNOBLAST; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION; LYMPH NODE; LYMPHADENOPATHY; LYMPHOID HYPERPLASIA; MALE; PRESCHOOL CHILD; REACTIVE LYMPHADENOPATHY; REED STERNBERG CELL; RETROSPECTIVE STUDY; SCHOOL CHILD;

ADOLESCENT; ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HERPESVIRUS 8, HUMAN; HISTOCYTOCHEMISTRY; HIV INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHATIC DISEASES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 78149374296     PISSN: 03774929     EISSN: 09745130     Source Type: Journal    
DOI: 10.4103/0377-4929.72055     Document Type: Article

References (16)

1. Ioachim HL, Medeiros LJ. Ioachim's lymph node pathology. In: Ioachim HL, Medeiros LJ, editors. Human immunodeficiency virus lymphadenitis. 4th ed. Philadelphia: Lippincott William and Wilkins; 2009. p. 99-105.
2. Gellar SA, Said JW, Joshi VV. Anderson's Pathology. In: Damjanov I, Linder J editors. Acquired Immunodeficiency Syndrome (AIDS). 10th ed. Missouri: Mosby; 1996. p. 632-3.
3. Greene WC. The molecular biology of human immunodeficiency virus type 1 infection. N Engl J Med 1991;324:308-17.
4. Klatzmann D, Barré-Sinoussi F, Nugeyre MT, Danquet C, Vilmer E, Griscelli C, et al. Selective tropism of lymphadenopathy associated virus (LAV) for helper-inducer T lymphocytes. Science 1984;225:59-64.
5. Stanley MW, Frizzera G. Diagnosis specificity of histologic features in lymph node biopsy specimens from patients at risk for the acquired immunodeficiency syndrome. Hum Pathol 1983;17:1231-9.
6. O'Murchadha MT, Wolf BC, Neiman RS. The histologic features of hyperplastic lymphadenopathy in AIDS-related complex are nonspecific. Am J Surg Pathol 1987;11:94-9.
7. Wannakrairot P, Leong TY, Leong AS. The morphological spectrum of lymphadenopathy in HIV infected patients. Pathology 2007;39:223-7.
8. Dorsett BH, Cronin W, Ioachim HL. Presence and prognostic significance of antilymphocyte antibodies in symptomatic and asymptomatic human immunodeficiency virus infection. Arch Intern Med 1990;150:1025-8.
9. Kalungi S, Wabinga H, Bostad L. Reactive lymphadenopathy in Ugandan patients and its relationship to EBV and HIV infection. APMIS 2009;117:302-7.
10. Uccini S, Monardo F, Vitolo D, Faggioni A, Gradilone A, Aglianó AM, et al. Human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) antigens and genome in lymph nodes of HIV-positive patients affected by persistent generalized lymphadenopathy (PGL). Am J Clin Pathol 1989;92:729-35.
11. Pietersma F, Piriou E, van Baarle D. Immune surveillance of EBVinfected B cells and the development of non-Hodgkin lymphomas in immunocompromised patients. Leuk Lymphoma 2008;49:1028-41.
12. Gujral S, Shet TM, Kane SV. Morphological spectrum of AIDS-related plasmablastic lymphomas. Indian J Pathol Microbiol 2008;51:121-4.
13. Agarwal B, Ramanathan U, Lokeshwas N, Nair R, Gopal R, Bhatia K, et al. Lymphoid neoplasms in HIV-positive individuals in India. J Acquir Immun Defic Syndr 2002;29:181-3.
14. Dupin N, Diss TL, Kellam P, Tulliez M, Du MQ, Sicard D, et al. HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8 positive plasmablastic lymphoma. Blood 2000;95: 1406-12.
15. O'Leary J, Kennedy M, Howells D, Silva I, Uhlmann V, Luttich K, et al. Cellular localisation of HHV-8 in Castleman's disease: is there a link with lymph node vascularity? Mol Pathol 2000;53:69-76.
16. Vassallo J, Rebouças I, Brousset P. Detection of HHV-8 in reactive lymphoid tissue of patients from São Paulo state, Brazil. J Clin Pathol 2002;55:78-9.