Neurobiology of REM sleep

Handbook of Clinical Neurology

Volumn 98, Issue C, 2011, Pages 151-171

  MCCarley, Robert W ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 AMINOBUTYRIC ACID; NEUROPEPTIDE; OREXINS; SEROTONIN; SEROTONIN AGONIST; SIGNAL PEPTIDE;

ANIMAL; BIOLOGICAL MODEL; BOOK; BRAIN; CYTOLOGY; DRUG EFFECT; EYE MOVEMENT; HISTOLOGY; HUMAN; METABOLISM; NERVE CELL; NERVE TRACT; NEUROBIOLOGY; PHYSIOLOGY; REM SLEEP;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BRAIN; EYE MOVEMENTS; GAMMA-AMINOBUTYRIC ACID; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; NEURAL PATHWAYS; NEUROBIOLOGY; NEURONS; NEUROPEPTIDES; SEROTONIN; SEROTONIN RECEPTOR AGONISTS; SLEEP, REM;

EID: 78149366189     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-52006-7.00010-1     Document Type: Book

References (105)

1. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1981, 1:876-886.
2. Aston-Jones G., Bloom F.E. Norepinephrine-containing locus coeruleus neurons in behaving rat exhibit pronounced responses to non-noxious environmental stimuli. J Neurosci 1981, 1:887-900.
3. Auerbach S.B., Minzenberg M.J., Wilkinson L.O. Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection: dialysate serotonin reflects neuronal release. Brain Res 1989, 499:281-290.
4. Beuckmann C.T., Sinton C.M., Williams S.C., et al. Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat. J Neurosci 2004, 24:4469-4477.
5. Bjorvatn B., Fagerland S., Eid T., et al. Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. Brain Res 1997, 770:81-88.
6. Boissard R., Gervasoni D., Schmidt M.H., et al. The rat ponto-medullary network responsible for paradoxical sleep onset and maintenance: a combined microinjection and functional neuroanatomical study. Eur J Neurosci 2002, 16:1959-1973.
7. Bourgin P., Escourrou P., Gaultier C., et al. Induction of rapid eye movement sleep carbachol infusion into the pontine reticular formation in the rat. Neuroreport 1995, 6:532-536.
8. Brooks D.C., Gershon M.D., Simon R.P. Brainstem serotonin depletion and ponto-geniculo-occipital wave activity in the cat treated with reserpine. Neuropharmacol 1972, 11:511-520.
9. Caballero A., De Andres I. Unilateral lesions in locus coeruleus area enhance paradoxical sleep. Electroencephalogr Clin Neurophysiol 1986, 64:339-346.
10. Cespuglio R., Gomez M.E., Walker E., et al. Effets du refroidissement et de la stimulation des noyaux du système du raphé sur les états de vigilance chez le chat. Electroencephalogr Clin Neurophysiol 1979, 47:289-308.
11. Cespuglio R., Faradji H., Gomez M.E., et al. Single unit recordings in the nuclei raphe dorsalis and magnus during the sleep-waking cycle of semi-chronic prepared cats. Neurosci Lett 1981, 24:133-138.
12. Cespuglio R., Gomez M.E., Faradji H., et al. Alterations in the sleep-waking cycle induced by cooling of the locus coeruleus area. Electroencephalogr Clin Neurophysiol 1982, 54:570-578.
13. Chen L., Thakkar M., Winston S., et al. RNA interference induces orexin knockdown and sleep changes in rats. Sleep 2005, 28:A340.
14. Chen L., Thakkar M.M., Winston S., et al. REM sleep changes in rats induced by siRNA-mediated orexin knockdown. Eur J Neurosci 2006, 24:2039.
15. Chen L., Brown R.E., McKenna J.T., et al. Animal models of narcolepsy. CNS Neurol Disord Drug Targets 2009, 8:296-308.
16. Coleman C.G., Lydid R., Baghdoyan H.A. Acetylcholine release in the pontine reticular formation of C57BL/6J mouse is modulated by non-M1 musacarinic receptors. Neurosci 2004, 126:831-838.
17. Coleman C.G., Lydic R., Baghdoyan H.A. M2 musacarinic receptors in pontine formation of C57BL/6J mouse contribute to rapid eye movement sleep generation. Neurosci 2004, 126:821-830.
18. Deurveilher S., Hars B., Hennevin E. Pontine microinjection of carbachol does not reliably enhance paradoxical sleep in rats. Sleep 1997, 20:593-607.
19. El Mansari M., Sakai K., Jouvet M. Responses of presumed cholinergic mesopontine tegmental neurons to carbachol microinjections in freely moving cats. Exp Brain Res 1990, 83:115-123.
20. Feinberg I., Thode H.C., Chugani H.T., et al. Gamma function describes maturational curves for delta wave amplitude, cortical metabolic rate and synaptic density. J Theor Biol 1990, 142:149-161.
21. Fields R.D., Feleke E., Stevens B., et al. Action potential-dependent regulation of gene expression: temporal specificity in Ca21, cAMP-responsive element binding proteins, and mitogen-activated protein kinase signaling. J Neurosci 1997, 17(19):7252-7266.
22. Foote S.L., Aston-Jones G., Bloom F.E. Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal. Proc Natl Acad Sci U S A 1980, 77:3033-3037.
23. Fornal C., Auerbach S., Jacobs B.L. Activity of serotonin containing neurons in nucleus raphe magnus in freely moving cats. Exp Neurol 1985, 88:590-608.
24. Gerber U., Stevens D.S., McCarley R.W., et al. A muscarinic-gated conductance increase in medial pontine reticular neurons of the rat in vitro. J Neurosci 1991, 11:3861-3867.
25. Gervasoni D., Darracq L., Fort P., et al. Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep. Eur J Neurosci 1998, 10:964-970.
26. Gervasoni D., Peyron C., Rampon C., et al. Role and origin of the GABAergic innervation of dorsal raphe serotonergic neurons. J. Neurosci 2000, 20:4217-4225.
27. Gnadt J.W., Pegram G.V. Cholinergic brainstem mechanisms of REM sleep in the rat. Brain Res 1986, 384:29-41.
28. Goutagny R., Comte J.C., Salvert D., et al. Paradoxical sleep in mice lacking M3 and M2/M4 muscarinic receptors. Neuropsychobiol 2005, 52:140-146.
29. Greene R.W., Gerber U., McCarley R.W. Cholinergic activation of medial pontine reticular formation neurons in vitro. Brain Res 1989, 476:154-159.
30. Hendricks J.C., Morrison A.R., Mann G.L. Different behaviors during paradoxical sleep without atonia depend on pontine lesion site. Brain Res 1982, 239:81-105.
31. Hobson J.A., McCarley R.W., Wyzinski P.A., et al. Reciprocal firing by two neuronal groups during the sleep cycle. Soc Neurosci Abstr 1973, 3:373.
32. Hobson J.A., McCarley R.W., Wyzinski P.W. Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups. Science 1975, 189:55-58.
33. Hobson J.A., McCarley R.W., Nelson J.P. Location and spike-train characteristics of cells in anterodorsal pons having selective decreases in firing rate during desynchronized sleep. J Neurophysiol 1983, 50:770-783.
34. Honda T., Semba K. An ultrastructural study of cholinergic and non-cholinergic neurons in the laterodorsal and pedunculopontine tegmental nuclei in the rat. Neuroscience 1995, 68:837-853.
35. Imeri L., De Simoni M.G., Giglio R., et al. Changes in the serotonergic system during the sleep-wake cycle: simultaneous polygraphic and voltammetric recordings in hypothalamus using a telemetry system. Neuroscience 1994, 58:353-358.
36. Ito K., Yanagihara M., Imon L., et al. Intracellular recordings of pontine medial gigantocellular tegmental field neurons in the naturally sleeping cat: behavioral state-related activity and soma size difference in order of recruitment. Neuroscience 2002, 114:23.
37. Jones B.E. The organization of central cholinergic systems and their functional importance in sleep-waking states. Progr Brain Res 1993, 98:61-71.
38. Jones B.E., Harper S.T., Halaris A.E. Effects of locus coeruleus lesions upon cerebral monoamine content, sleep-wakefulness states and the response to amphetamine in the cat. Brain Res 1977, 124:473-496.
39. Jouvet M. Recherches sur les structures nerveuses et les mécanismes responsables des différentes phases du sommeil physiologique. Arch Ital Biol 1962, 100:125.
40. Jouvet M. What does a cat dream about?. Trends Neurosci 1979, 2:15-16.
41. Principles of Neural Science 2000, McGraw-Hill, New York. E. Kandel, J.H. Schwarz, T.M. Jessell (Eds.).
42. Kayama Y., Ohta M., Jodo E. Firing of " possibly" cholinergic neurons in the rat laterodorsal tegmental nucleus during sleep and wakefulness. Brain Res 1992, 569:210-220.
43. Kohlmeier K.A., Reiner P.B. Noradrenaline excites non-cholinergic laterodorsal tegmental neurons via two distinct mechanisms. Neuroscience 1999, 93:619-630.
44. Leonard C.S., Llinás R.R. Serotonergic and cholinergic inhibition of mesopontine cholinergic neurons controlling REM sleep: an in vitro electrophysiological study. Neuroscience 1994, 59:309-330.
45. Levine E.S., Jacobs B.L. Neurochemical afferents controlling the activity of serotonergic neurons in the dorsal raphe nucleus: microiontophoretic studies in the awake cat. J Neurosci 1992, 12:4037-4044.
46. Li X., Rainnie D.G., McCarley R.W., et al. Presynaptic nicotinic receptors facilitate monoaminergic transmission. J Neurosci 1998, 18:1904-1912.
47. Lu J., Sherman D., Devor M., et al. A putative flip-flop switch for control of REM sleep. Nature 2006, 441:589.
48. Luebke J.I., Greene R.W., Semba K., et al. Serotonin hyperpolarizes cholinergic low-threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro. Proc Natl Acad Sci U S A 1992, 89:743-747.
49. Lydic R., McCarley R.W., Hobson J.A. The time-course of dorsal raphe discharge, PGO waves, and muscle tone averaged across multiple sleep cycles. Brain Res 1983, 274:365-370.
50. Lydic R., McCarley R.W., Hobson J.A. Serotonin neurons and sleep. I. Long term recordings of dorsal raphe discharge frequency and PGO waves. Arch Ital Biol 1987, 125:317-343.
51. Lydic R., McCarley R.W., Hobson J.A. Serotonin neurons and sleep. II. Time course of dorsal raphe discharge, PGO waves, and behavioral states. Arch Ital Biol 1987, 126:1-28.
52. McCarley R.W. A model for the periodicity of brainstem neuronal discharges during the sleep cycle. Sleep Res 1973, 2:30.
53. McCarley R.W. Control of sleep-waking state alteration in Felix domesticus. Neuroscience Symposia 1978, vol III:90. Society for Neuroscience, Bethesda, MA. J.A. Ferrendelli (Ed.).
54. McCarley R.W. Mechanisms and models of REM sleep control. Arch Ital Biol 2004, 142:429-468.
55. McCarley R.W., Hobson J.A. Neuronal excitability modulation over the sleep cycle: a structural and mathematical model. Science 1975, 189:58-60.
56. McCarley R.W., Massaquoi S.G. A limit cycle mathematical model of the REM sleep oscillator system. Am J Physiol 1986, 251:R1011-R1029.
57. McCarley R.W., Massaquoi S.G. Further discussion of a model of the REM sleep oscillator. Am J Physiol 1986, 251:R1033-R1036.
58. McCarley R.W., Massaquoi S.G. The limit cycle reciprocal interaction model of REM cycle control: new neurobiological structure. J Sleep Res 1992, 1:132.
59. McCarley R.W., Greene R.W., Rainnie D., et al. Brainstem neuromodulation and REM sleep. Sem Neurosci 1995, 7:341-354.
60. McGinty D.J., Harper R.M. Dorsal raphe neurons: depression of firing during sleep in cats. Brain Res 1976, 101:569-575.
61. Maloney K.J., Mainville L., Jones B.E. Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery. J Neurosci 1999, 19:3057-3072.
62. Marks G.A., Birabil C.G. Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation. Neurosci 1998, 86:29-37.
63. Marks G.A., Kramer G.L., Birabil C.G. GABAergic mechanisms in the REM sleep induction zone of the rat. Sleep 2003, 26(Abstract Supplement):A8.
64. Massaquoi S.G., McCarley R.W. Extension of the limit cycle reciprocal interaction model of REM cycle control: an integrated sleep control model. J Sleep Res 1992, 1:138-143.
65. Merchant-Nancy H., Vazquaz J., Garcia F., et al. Brain distribution of c-fos expression as a result of prolonged rapid eye movement (REM) sleep period duration. Brain Res 1995, 681:15-22.
66. Mitani A., Ito K., Hallanger A.E., et al. Cholinergic projections from the laterodorsal and pedunculopontine tegmental nuclei to the pontine gigantocellular tegmental field in the cat. Brain Res 1988, 451:397-402.
67. Nitz D.A., Siegel J.M. GABA release in the locus coeruleus as a function of sleep/wake state. Neuroscience 1997, 78:795-801.
68. Nitz D.A., Siegel J.M. Inhibitory amino acid neurotransmission in the dorsal raphe nucleus during sleep/wake states. Am J Physiol 1997, 273:R451-454.
69. Paxinos G.T., Watson C. The rat brain. Stereotaxic Coordinates 1997, Academic Press, San Diego.
70. Petitjean F., Sakai K., Blondaux C., et al. Hypersomnia by isthmic lesion in cat. II. Neurophysiological and pharmacological study. Brain Res 1975, 88:439-453.
71. Pollack M.D., Mistlberger R.E. Microinjection of neostigmine into the pontine reticular formation of the mouse: further evaluation of a proposed REM sleep enhancement technique. Brain Res 2005, 1031:253-267.
72. Portas C.M., McCarley R.W. Behavioral state-related changes of extracellular serotonin concentration in the dorsal raphe nucleus: a microdialysis study in the freely moving cat. Brain Res 1994, 648:306-312.
73. Portas C.M., Thakkar M., Rainnie D., et al. Microdialysis perfusion of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in the dorsal raphe nucleus decreases serotonin release and increases rapid eye movement sleep in the freely moving cat. J Neurosci 1996, 16:2820-2828.
74. Rasmussen K., Heym J., Jacobs B.L. Activity of serotonin containing neurons in nucleus centralis superior of freely moving cats. Exp Neurol 1984, 83:302-317.
75. Ruch-Monachon M.A., Jalfre M., Haefeley W. Drugs and PGO waves in the lateral geniculate body of the curarized rat. Arch Int Pharmacodyn Thér 1976, 219:251-346.
76. Sakai K., Crochet S. Serotonergic dorsal raphe neurons cease firing by disfacilitation during paradoxical sleep. Neuroreport 2000, 11:3237-3241.
77. Sakai K., Crochet S. Role of dorsal raphe neurons in paradoxical sleep generation in the cat: no evidence for a serotonergic mechanism. Eur J Neurosci 2001, 13:103-112.
78. Sakai K., Vanni-Mercier G., Jouvet M. Evidence for the presence of PS-Off neurons in the ventromedial oblongata of freely moving cats. Exp Brain Res 1983, 49:311-314.
79. Sanford L.D., Ross R.J., Seggos A.E., et al. Central administration of two 5-HT receptor agonists: effect on REM sleep initiation and PGO waves. Pharmacol Biochem Behav 1994, 49:93-100.
80. Sanford L.D., Tang X., Xiao J., et al. GABAergic regulation of REM sleep in reticularis pontis oralis and caudalis in rats. J Neurophysiol 2003, 90:938-945.
81. Sastre J.P., Jouvet M. Le comportement onirique du chat. Physiol Behav 1979, 22:979-989.
82. Sastre J.P., Buda C., Kitahama K., et al. Importance of the ventrolateral region of the periaqueductal gray and adjacent tegmentum in the control of paradoxical sleep as studied by muscimol microinjections in the cat. Neuroscience 1996, 74:415-426.
83. Satinoff E. Thermal influences on REM sleep. Clinical Physiology of Sleep 1988, 135-144. American Physiological Society, Bethesda, MA. R. Lydic, J.F. Biebuyck (Eds.).
84. Semba K., Fibiger H.C. Afferent connections of the laterodorsal and the pedunculopontine tegmental nuclei in the rat: a retro- and antero-grade transport and immunohistochemical study. J Comp Neurol 1992, 323:387-410.
85. Simon R.P., Gershon M.P., Brooks D.C. The role of the raphe nuclei in the regulation of ponto-geniculo-occipital wave activity. Brain Res 1973, 58:313-330.
86. Sprouse J.S., Aghajanian G.K. Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists. Synapse 1987, 1:3-9.
87. Steinfels G.F., Heym J., Strecker R.E., et al. Behavioral correlates of dopaminergic unit activity in freely moving cats. Brain Res 1983, 258:217-228.
88. Steininger T.L., Wainer B.H., Blakely R.D., et al. Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic anterograde tracing and immunohistochemical study. J Comp Neurosci 1997, 382:302-322.
89. Steriade M., McCarley R.W. Brain Control of Wakefulness and Sleep 2005, Kluwer Academic/Plenum, New York, New York.
90. Steriade M., Datta S., Paré D., et al. Neuronal activities in brainstem cholinergic nuclei related to tonic activation processes in thalamocortical systems. J Neurosci 1990, 10:2541-2559.
91. Strecker R.E., Thakkar M.M., Porkka-Heiskanen T., et al. Behavioral state-related changes of extracellular serotonin concentration in the pedunculopontine tegmental nucleus: a microdialysis study in freely moving animals. Sleep Res Online 1999, 2:21-27. http://www.sro.org/1999/strecker/21/.
92. Swanson L.W. Brain Maps: Structure of the Rat Brain 1992, Elsevier, New York.
93. Taguchi O., Kubin L., Pack A.I. Evocation of postural atonia and respiratory depression by pontine carbachol in the decerebrate rat. Brain Res 1992, 595:107-115.
94. Thakkar M., Portas C.M., McCarley R.W. Chronic low amplitude electrical stimulation of the laterodorsal tegmental nucleus of freely moving cats increases REM sleep. Brain Res 1996, 723:223-227.
95. Thakkar M.M., Strecker R.E., McCarley R.W. Behavioral state control through differential serotonergic inhibition in the mesopontine cholinergic nuclei: a simultaneous unit recording and microdyalisis study. J Neurosci 1998, 18:5490-5497.
96. Thakkar M., Strecker R., McCarley R.W. Phasic but not tonic REM selective discharge of periaqueductal gray neurons in freely behaving animals: relevance to postulates of GABAergic inhibition of monoaminergic neurons. Brain Res 2002, 945:276-280.
97. Thakkar M.M., Tao R., Ma Z., et al. GABA release in the mPRF: role in the regulation of sleep-wakefulness. Sleep 2004, 27(Abstract Supplement).
98. Thakkar M.M., Tao R., Yunren B., et al. GABA release in the pontine reticular formation is lowest during REM sleep. Soc Neurosci Abstr. 2004, Program no. 895:5.
99. Trulson M.F., Jacobs B.L. Raphe unit activity in freely moving cats: correlation with level of behavioral arousal. Brain Res 1979, 163:135-150.
100. Verret L., Leger L., Fort P., et al. Cholinergic and noncholinergic brainstem neurons expressing Fos after paradoxical (REM) sleep deprivation and recovery. Eur J Neurosci 2005, 21:2488-2504.
101. Webster H.H., Jones B.E. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic area in the cat. II. Effects upon sleep-waking states. Brain Res 1988, 458:285-302.
102. Wilkinson L.O., Auerbach S.B., Jacobs B.L. Extracellular serotonin levels change with behavioral state but not with pyrogen-induced hyperthermia. J Neurosci 1991, 11:2732-2741.
103. Williams J.A., Reiner P.B. Noradrenaline hyperpolarizes identified rat mesopontine cholinergic neurons in vitro. J Neurosci 1993, 13:3878-3883.
104. Xi M.C., Morales F.R., Chase M.H. A GABAergic pontine reticular system is involved in the control of wakefulness and sleep. Sleep Res Online 1999, 2:43-48.
105. Xi M.C., Morales F.R., Chase M.H. Induction of wakefulness and inhibition of active (REM) sleep by GABAergic processes in the nucleus pontis oralis. Arch Ital Biol 2001, 139:125-145.