Malignant high-grade histological transformation of inflammatory myofibroblastic tumour associated with amplification of TPM3-ALK

Journal of Clinical Pathology

Volumn 63, Issue 11, 2010, Pages 1040-1041

  Zhang, Hongying ^a   Erickson Johnson, Michele ^b   Wang, Xiaoke ^b   Bahrami, Armita ^b   Medeiros, Fabiola ^b   Lonzo, Melissa L ^b   Oliveira, Andre M ^b  

^a SICHUAN UNIVERSITY   (China)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; DOXORUBICIN; IFOSFAMIDE; TROPOMYOSIN; TROPOMYOSIN 3; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ADULT; CASE REPORT; CELL PROLIFERATION; COMPUTER ASSISTED TOMOGRAPHY; DNA SEQUENCE; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE AMPLIFICATION; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LETTER; LIVER INJURY; LIVER METASTASIS; MALE; MESENTERY TUMOR; MITOSIS; MOLECULAR BIOLOGY; MULTIPLE CYCLE TREATMENT; PLASMA CELL GRANULOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOMA; SPINDLE CELL;

ABDOMINAL NEOPLASMS; ADULT; DISEASE PROGRESSION; FATAL OUTCOME; GENE AMPLIFICATION; HUMANS; MALE; NEOPLASMS, MUSCLE TISSUE; ONCOGENE PROTEINS, FUSION; PROTEIN-TYROSINE KINASES; SARCOMA; TROPOMYOSIN;

EID: 78149359896     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2010.080705     Document Type: Letter

References (8)

1. Coffin CM, Fletcher JA. Inflammatory myofibroblastic tumour. In: Fletcher CDM, Unni KK, Mertens F, eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. World Health Organization Classification of Tumours. Lyon: IARC Press, 2002:91-3.
2. Chen ST, Lee JC. An inflammatory myofibroblastic tumour in liver with ALK and RANBP2 gene rearrangement: combination of distinct morphologic, immunohistochemical, and genetic features. Hum Pathol 2008;39:1854-8.
3. Debelenko LV, Arthur DC, Pack SD, et al. Identification of CARS-ALK fusion in primary and metastatic lesions of an inflammatory myofibroblastic tumour. Lab Invest 2003;83:1255-65.
4. Gleason BC, Hornick JL. Inflammatory myofibroblastic tumours: where are we now? J Clin Pathol 2008;61:428-37.
5. Griffin CA, Hawkins AL, Dvorak C, et al. Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res 1999;59:2776-80.
6. Lawrence B, Perez-Atayde A, Hibbard MK, et al. TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol 2000;157:377-84.
7. Coffin CM, Hornick JL, Fletcher CD. Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases. Am J Surg Pathol 2007;31:509-20.
8. Hornick JL, Wang WL, Roy A, et al. Round cell inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK: an aggressive intra-abdominal variant [abstract]. Mod Pathol 2010;23:21A.