PH transients in hydroxyapatite chromatography columns-Effects of operating conditions and media properties

Journal of Chromatography A

Volumn 1217, Issue 48, 2010, Pages 7573-7578

  Dattolo, Laura ^a   Keller, Emily L ^a   Carta, Giorgio ^a  

^a University of Virginia   (United States)

Author keywords

Hydroxyapatite; Managing; Modeling; PH transitions

Indexed keywords

DEVELOPED MODEL; HYDROXYAPATITE CHROMATOGRAPHY; KEY VARIABLES; MANAGING; MEDIA PROPERTIES; MODELING; OPERATING CONDITION; PH DROP; PH TRANSIENTS; PROTON EXCHANGE; SALT CONCENTRATION; SALT GRADIENT; STEP CHANGES; SURFACE AREA;

AMINO ACIDS; APATITE; CONCENTRATION (PROCESS); DROPS; HYDROXYAPATITE; PROTONS;

PH EFFECTS;

BUFFER; HYDROXYAPATITE; PROTON; SODIUM CHLORIDE;

ALKALINITY; ARTICLE; CONTROLLED STUDY; DENSITY GRADIENT; EQUILIBRIUM CONSTANT; FLOW RATE; ION EXCHANGE CHROMATOGRAPHY; MAGNITUDE ESTIMATION METHOD; PARTICLE SIZE; PH; PHASE TRANSITION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

BUFFERS; CHROMATOGRAPHY, ION EXCHANGE; DURAPATITE; PARTICLE SIZE;

EID: 78149358927     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.10.026     Document Type: Article

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