Pregnancy in autoimmune rheumatic diseases: The importance of counselling for old and new challenges

Autoimmunity Reviews

Volumn 10, Issue 1, 2010, Pages 51-54

  Andreoli, Laura ^a   Bazzani, Chiara ^a   Taraborelli, Mara ^a   Reggia, Rossella ^a   Lojacono, Andrea ^a   Brucato, Antonio ^b   Meroni, Pier Luigi ^c   Tincani, Angela ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Policlinico San Marco   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Anti TNF drugs; Antiphospholipid Syndrome; Lupus nephritis; Pregnancy; Rheumatic diseases; Systemic sclerosis

Indexed keywords

ABATACEPT; ADALIMUMAB; ETANERCEPT; INFLIXIMAB; LEFLUNOMIDE; METHOTREXATE; PHOSPHOLIPID ANTIBODY; RITUXIMAB; TOCILIZUMAB; TUMOR NECROSIS FACTOR INHIBITOR;

ANTIPHOSPHOLIPID SYNDROME; CHRONIC ARTHRITIS; COUNSELING; HUMAN; PREGNANCY; PREGNANCY OUTCOME; PREMATURE LABOR; REVIEW; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; THROMBOSIS;

AUTOIMMUNE DISEASES; COUNSELING; FEMALE; HUMANS; IMMUNOTHERAPY; PREGNANCY; PREGNANCY COMPLICATIONS; RHEUMATIC DISEASES;

EID: 78149357080     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2010.08.004     Document Type: Review

References (38)

1. Clowse M.E. Lupus activity in pregnancy. Rheum Dis Clin North Am 2007, 33:237-252.
2. Gladman D.D., Tandon A., Ibanez D., Urowitz M.B. The effect of lupus nephritis on pregnancy outcome and fetal and maternal complications. J Rheumatol 2010, 37:754-758.
3. Imbasciati E., Tincani A., Gregorini G., Doria A., Moroni G., Cabiddu G., et al. Pregnancy in women with pre-existing lupus nephritis: predictors of fetal and maternal outcome. Nephrol Dial Transplant 2009, 24:519-525.
4. Doria A., Tincani A., Lockshin M. Challenges of lupus pregnancies. Rheumatology 2008, 47:iii9-iii12.
5. Biggioggero M., Meroni P.L. The geoepidemiology of the antiphospholipid syndrome. Autoimmun Rev 2010, 9:A299-A304.
6. Cervera R. Lessons from the "Euro-phospholipid" project. Autoimmun Rev 2008, 7:174-178.
7. Ziakas P.D., Pavlou M., Voulgarelis M. Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss: a systematic review and meta-analysis. Obstet Gynecol 2010, 115:1256-1262.
8. Erkan D., Patel S., Nuzzo M., Gerosa M., Meroni P.L., Tincani A., et al. Management of the controversial aspects of the antiphospholipid syndrome pregnancies: a guide for clinicians and researchers. Rheumatology (Oxford) 2008, (suppl.3):iii23-iii27.
9. Rotar Z., Rozman B., de Groot P.G., Sanmarco M., Shoenfeld Y., Meroni P.L., et al. Sixth meeting of the European Forum on antiphospholipid antibodies. How to improve the understanding of the antiphospholipid syndrome?. Lupus 2009, 18:53-60.
10. Ruffatti A, Favaro M, Tonello M, Visentin M.S., De Carolis S, Botta A, et al. Risk factors for pregnancy failure in patients with antiphospholipid syndrome treated with conventional therapies. A multicentric case-control study. Submitted for publication .
11. Ruffatti A., Calligaro A., Hoxha A., Trevisanuto D., Ruffatti A.T., Gervasi M.T., et al. Laboratory and clinical features of pregnant women with antiphospholipid syndrome and neonatal outcome. Arthritis Care Res 2010, 62:302-307.
12. Ranque B., Mouthon L. Geoepidemiology of systemic sclerosis. Autoimm Rev 2010, 9:A311-A318.
13. Maymon R., Fejgin M., Ben-Aderet N., Bahary C. Scleroderma and pregnancy. Acta Obstet Gynecol Scand 1989, 68:469-470.
14. Karlen J.R., Cook W.A. Renal scleroderma and pregnancy. Obstet Gynecol 1974, 44:349-354.
15. Steen V.D. Pregnancy in women with systemic sclerosis. Obstet Gynecol 1999, 94:15-20.
16. Steen V.D., Conte C., Day N., Ramsey-Goldman R., Medsger T.A. Pregnancy in women with systemic sclerosis. Arthritis Rheum 1989, 32:151-157.
17. Whanchu A., Misra R. Pregnancy outcome in systemic sclerosis. J Assoc Physicians India 1996, 44:637-640.
18. Jiménez F.X., Simeón C.P., Fonollosa V., Espinach J., Solans R., Lima J., et al. M. Scleroderma and pregnancy: obstetrical complications and the impact of pregnancy on the course of the disease. Med Clin (Barc) 1999, 113:761-764.
19. Sampaio-Barros P.D., Samara A.M., Marques Neto J.F. Gynaecologic history in systemic sclerosis. Clin Rheumatol 2000, 19:184-187.
20. Steen V.D., Medsger T.A. Fertility and pregnancy outcome in women with systemic sclerosis. Arthritis Rheum 1999, 42:763-768.
21. Chakravarty E.F., Khanna D., Chung L. Pregnancy outcome in systemic sclerosis, primary pulmonary hypertension, and sickle cell disease. Obstet Gynecol 2008, 111:927-934.
22. Bernatsky S., Hudson M., Pope J., Vinet E., Markland J., Robinson D., et al. Assessment of reproductive history in systemic sclerosis. Arthritis Rheum 2008, 59:1661-1664.
23. Taraborelli M., Ramoni V. Pregnancy and systemic sclerosis: an Italian prospective multicentric study. Clin Exp Rheum 2010, 28(2):S80. Suppl.58.
24. Lambova S., Müller-Ladner U. Pulmonary arterial hypertension in systemic sclerosis. Autoimmun Rev 2010, epub ahead of print.
25. Ostensen M., Villiger P.M. The remission of rheumatoid arthritis during pregnancy. Semin Immunopathol 2007, 29:185-191.
26. Nelson J.L., Ostensen M. Pregnancy and rheumatoid arthritis. Rheum Dis Clin North Am 1997, 23:195-212.
27. Ostensen M., Fuhrer L., Mathieu R., Seitz M., Villiger P.M. A prospective study of pregnant patients with rheumatoid arthritis and ankylosing spondylitis using validated clinical instruments. Ann Rheum Dis 2004, 63:1212-1217.
28. Barrett J.H., Brennan P., Fiddler M., Silman A.J. Does rheumatoid arthritis remit during pregnancy and relapse postpartum? Results from a nationwide study in the United Kingdom performed prospectively from late pregnancy. Arthritis Rheum 1999, 42:1219-1227.
29. de Man Y.A., Dolhain R.J., van de Geijn F.E., Willemsen S.P., Hazes J.M. Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheum 2008, 59:1241-1248.
30. Ostensen M., Forger F., Nelson J.L. Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum. Ann Rheum Dis 2005, 64:839-844.
31. Lloyd M.E., Carr M., MC Elhatton P., Hall G.M., Hughes R.A. The effect of methotrexate on pregnancy, fertility and lactation. QJ Med 1999, 92:551-563.
32. Brent R.L. Teratogen update: reproductive risks of leflunomide (Arava): a pyrimidine synthesis inhibitor: counseling women taking leflunomide before or during pregnancy and men taking leflunomide who are contemplating fathering a child. Teratology 2001, 63:106-112.
33. Martìnez Lopez J.A., Loza E., Carmona L. Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding). Clin Exp Rheumatol 2009, 27:678-684.
34. Chambers C.D., Johnson D.L., Robinson L.K., Braddock S.R., Xu R., Lopez-Jimenez J., et al. Birth outcomes in women who have taken leflunomide during pregnancy. Arthritis Rheum 2010, 62:1494-1503.
35. Ostensen M., Förger F. Management of RA medications in pregnant patients. Nat Rev Rheumatol 2009, 5:382-390.
36. Ostensen M., Lockshin M., Doria A., Valesini G., Meroni P., Gordon C., et al. Update on safety during pregnancy of biological agents and some immunosuppressive anti-rheumatic drugs. Rheumatology (Oxford) 2008, 47:iii28-iii31.
37. Vinet E., Pineau C., Gordon C., Clarke A.E., Bernatsky S. Biologic therapy and pregnancy outcomes in women with rheumatic diseases. Arthritis Rheum 2009, 61:587-592.
38. Villiger P.M., Caliezi G., Cottin V., Forger F., Senn A., Ostensen M. Effects of TNF antagonists on sperm characteristics in patients with spondyloarthritis. Ann Rheum Dis 2010, epub ahead of print.