Pendrin modulates ENaC function by changing luminal HCO3 -

Journal of the American Society of Nephrology

Volumn 21, Issue 11, 2010, Pages 1928-1941

  Pech, Vladimir ^a   Pham, Truyen D ^a   Hong, Seongun ^a   Weinstein, Alan M ^b   Spencer, Kathryn B ^a   Duke, Billy Jean ^a   Walp, Eric ^c   Kim, Young Hee ^a   Sutliff, Roy L ^a,c   Bao, Hui Fang ^a   Eaton, Douglas C ^a   Wall, Susan M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; ALDOSTERONE; EPITHELIAL SODIUM CHANNEL; PENDRIN;

ACID BASE BALANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; FEMALE; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY TUBULE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; URINE PH;

EID: 78149323416     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2009121257     Document Type: Article

References (42)

1. Royaux IE, Wall SM, Karniski LP, Everett LA, Suzuki K, Knepper MA, Green ED: Pendrin, encoded by the pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Proc Natl Acad Sci U S A 98: 4221-4226, 2001
2. Verlander JW, Hassell KA, Royaux IE, Glapion DM, Wang M-E, Everett LA, Green ED, Wall SM: Deoxycorticosterone upregulates Pds (Slc26a4) in mouse kidney: Role of pendrin in mineralocorticoid-induced hypertension. Hypertension 42: 356-362, 2003
3. Wall SM, Kim Y-H, Stanley L, Glapion DM, Everett LA, Green ED, Verlander JW: NaCl restriction upregulates renal Slc26a4 through subcellular redistribution: Role in Cl- conservation. Hypertension 44: 1-6, 2004
4. Verlander JW, Kim Y-H, Shin WK, Pham TD, Hassell KA, Beierwaltes WH, Green ED, Everett LA, Matthews SW, Wall SM: Dietary Cl- restriction upregulates pendrin expression within the apical plasma membrane of type B intercalated cells. Am J Physiol 291: F833-F839, 2006
5. Kim Y-H, Pech V, Spencer KB, Beierwaltes WH, Everett LA, Green ED, Shin WK, Verlander JW, Sutliff RL, Wall SM: Reduced ENaC expression contributes to the lower blood pressure observed in pendrin null mice. Am J Physiol 293: F1314-F1324, 2007
6. Wall SM, Hassell KA, Royaux IE, Green ED, Chang JY, Shipley GL, Verlander JW: Localization of pendrin in mouse kidney. Am J Physiol 284: F229-F241, 2003
7. Kim Y-H, Kwon T-H, Frische S, Kim J, Tisher CC, Madsen KM, Nielsen S: Immunocytochemical localization of pendrin in intercalated cell subtypes in rat and mouse kidney. Am J Physiol 283: F744-F754, 2002
8. Masilamani S, Kim G-H, Mitchell C, Wade JB, Knepper MA: Aldosterone- mediated regulation of ENaC α,β and γ subunit proteins in rat kidney. J Clin Invest 104: R19-R23, 1999
9. Pech V, Kim Y-H, Weinstein AM, Everett LA, Pham TD, Wall SM: Angiotensin II increases chloride absorption in the cortical collecting duct in mice through a pendrin-dependent mechanism. Am J Physiol 292: F914-F920, 2007
10. Snyder PM: Minireview: Regulation of epithelial Na+ channel trafficking. Endocrinology 146: 5079-5085, 2005
11. Kim G-H, Martin SW, Fernandez-Llama P, Masilamani S, Packer RK, Knepper MA: Long-term regulation of renal Na-dependent cotransporters and ENaC: Response to altered acid-base intake. Am J Physiol 279: F459-F467, 2000
12. Palmer LG, Frindt G: Effects of cell Ca and pH on Na channels from rat cortical collecting tubule. Am J Physiol 253: F333-F339, 1987
13. Shipway A, Danahay H, Williams JA, Tully DC, Backes BJ, Harris JL: Biochemical characterization of prostasin, a channel activating protease. Biochem Biophys Res Commun 324: 953-963, 2004
14. Faroqui S, Sheriff S, Amlal H: Metabolic acidosis has dual effects on sodium handling in rat kidney. Am J Physiol 291: F322-F331, 2006
15. Frische S, Kwon T-H, Frokiaer J, Madsen KM, Nielsen S: Regulated expression of pendrin in rat kidney in response to chronic NH4Cl or NaHCO3 loading. Am J Physiol 284: F584-F593, 2003
16. -. Am J Physiol 274: F1086-F1094, 1998
17. Sun X, Soleimani M, Petrovic S: Decreased expression of Slc26a4 (pendrin) and Slc26a7 in the kidneys of carbonic anhydrase II-deficient mice. Cell Physiol Biochem 21: 95-108, 2008
18. Weinstein AM: A mathematical model of distal nephron acidification: Diuretic effects. Am J Physiol 295: F1353-F1364, 2008
19. Kim Y-H, Verlander JW, Matthews SW, Kurtz I, Shin WK, Weiner ID, Everett LA, Green ED, Nielsen S, Wall SM: Intercalated cell H+/OH-transporter expression is reduced in Slc26a4 null mice. Am J Physiol 289: F1262-F1272, 2005
20. Collier DM, Snyder PM: Extracellular chloride regulates the epithelial sodium channel. J Biol Chem 284: 29320-29325, 2009
21. DuBose TD Jr.: Effect of carbonic anhydrase inhibition on superficial and deep nephron bicarbonate reabsorption in the rat. J Clin Invest 71: 55-65, 1983
22. Bailey MA, Giebisch G, Abbiati T, Aronson PS, Gawenis LR, Shull GE, Wang T: NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice. J Physiol 561.3: 765-775, 2004
23. Kemendy AE, Kleyman TR, Eaton DC: Aldosterone alters the open probability of amiloride-blockable sodium channels in A6 epithelia. Am J Physiol 263: C825-C837, 1992
24. Chang SS, Grunder S, Hanukoglu A, Rosler A, Mathew PM, Hanukoglu I, Schild L, Lu Y, Shimkets RA, Nelson-Williams C, Rossier BC, Lifton RP: Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalemic acidosis, pseudohypoaldosteronism type 1. Nat Genetics 12: 248-253, 1996
25. Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR Jr., Ulick S, Milora RV, Findling JW: Liddle's syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell 79: 407-414, 1994
26. Boudry JF, Stoner LC, Burg MB: Effect of acid lumen pH on potassium transport in renal cortical collecting tubules. Am J Physiol 230: 239-244, 1976
27. Stanton BA, Giebisch G: Effects of pH on potassium transport by renal distal tubule. Am J Physiol 242: F544-F551, 1982
28. Knepper M, Burg M: Organization of nephron function. Am J Physiol 244: F579-F589, 1983
29. Richardson RMA, Kunau RT Jr.: Bicarbonate reabsorption in the papillary collecting duct: Effect of acetazolamide. Am J Physiol 243: F74-F80, 1982
30. Buerkert J, Martin D, Trigg D: Segmental analysis of the renal tubule in buffer production and net acid formation. Am J Physiol 244: F442-F454, 1983
31. Yao L-J, Leitges M, Vallon V: Mice lacking protein kinase C beta present modest increases in systolic blood pressure and NH4Cl-induced metabolic acidosis. Kidney Blood Press Res 29: 36-42, 2006
32. Hallows KR, Wang H, Edinger RS, Butterworth MB, Oyster NM, Li H, Buck J, Levin LR, Johnson JP, Pastor-Soler NM: Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells. J Biol Chem 284: 5774-5783, 2009
33. Schuster VL: Cyclic adenosine monophosphate-stimulated anion transport in rabbit cortical collecting duct. J Clin Invest 78: 1621-1630, 1986
34. Hanley MJ, Kokko JP: Study of chloride transport across the rabbit cortical collecting tubule. J Clin Invest 62: 39-44, 1978
35. Everett LA, Belyantseva IA, Noben-Trauth K, Cantos R, Chen A, Thakkar SI, Hoogstraten-Miller SL, Kachar B, Wu DK, Green ED: Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome. Hum Mol Genet 10: 153-161, 2001
36. Wall SM, Knepper MA, Hassell KA, Fischer MP, Shodeinde A, Shin WK, Pham TD, Meyer JW, Lorenz JN, Beierwaltes WH, Dietz JR, Shull GE, Kim Y-H. Hypotension in NKCC1 null mice: Role of the kidneys. Am J Physiol 290: F409-F416, 2006
37. Brooks HL, Allred AJ, Beutler KT, Coffman TM, Knepper MA: Targeted proteomic profiling of renal Na+ transporter and channel abundances in angiotensin II type 1a receptor knockout mice. Hypertension 39: 470-473, 2002
38. Catalan MA, Nakamoto T, Gonzales-Begne M, Camden JM, Wall SM, Clarke LL, Melvin JE: CFTR and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland. J Physiol 588: 713-724, 2010
39. Terris J, Ecelbarger CA, Nielsen S, Knepper MA: Long-term regulation of four renal aquaporins in rats. Am J Physiol 271: F414-F422, 1996
40. + augments net acid secretion by a ouabain-sensitive mechanism in isolated perfused inner medullary collecting ducts. Am J Physiol 270: F432-F439, 1996
41. Bens M, Vallet V, Cluzeaud F, Pascual-Letallec L, Kahn A, Rafestin-Oblin ME, Rossier BC, Vandewalle A: Corticosteroid-dependent sodium transport in a novel immortilized mouse collecting duct principal cell line. J Am Soc Nephrol 10: 923-934, 1999
42. Marunaka Y, Eaton DC: Effects of vasopressin and cAMP on single amiloride-blockable Na channels. Am J Physiol 260: C1071-C1084, 1991