Functional analysis of the skin-swelling response to phytohaemagglutinin

Functional Ecology

Volumn 24, Issue 5, 2010, Pages 1081-1086

  Vinkler, Michal ^a,b   Bainová, Hana ^a   Albrecht, Tomáš ^a,b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF VERTEBRATE BIOLOGY   (Czech Republic)

Author keywords

Avian innate and adaptive immunity; Ecoimmunology; Ecological immunology; Ecotoxicology; Inflammatory response; PHA induced hypersensitivity; Phytohaemagglutinin; T cell mediated immunocompetence

Indexed keywords

ADAPTATION; BIOACTIVITY; BLOOD; ECOTOXICOLOGY; EXPERIMENTAL STUDY; HISTOLOGY; IMMUNE RESPONSE; IMMUNITY; IMMUNOCOMPETENCE; PROTEIN; SKIN; SONGBIRD;

AVES; BOVINAE; TAENIOPYGIA GUTTATA;

EID: 78149289134     PISSN: 02698463     EISSN: 13652435     Source Type: Journal    
DOI: 10.1111/j.1365-2435.2010.01711.x     Document Type: Article

References (34)

1. Airo, R., Mihailes, E., Astaldi, G. & Meardi, G. (1967) Skin reactions to phytohaemagglutinin. Lancet, 1, 899-900.
2. Ardia, D.R. & Schat, K.A. (2008) Ecoimmunology. Avian Immunology (eds F. Davison, B. Kaspers & K.A. Schat), pp. 421-441, Academic Press, Elsevier, London.
3. Bonato, M., Evans, M.R., Hasselquist, D. & Cherry, M.I. (2009) Male coloration reveals different components of immunocompetence in ostriches, Struthio camelus. Animal Behaviour, 77, 1033-1039.
4. Bonforte, R.J., Glade, P.R., Siltzbac, L.E. & Topilsky, M. (1972) Phytohemagglutinin skin-test - possible in-vivo measure of cell-mediated immunity. Journal of Pediatrics, 81, 775-780.
5. Brommer, J.E. (2004) Immunocompetence and its costs during development: an experimental study in blue tit nestlings. Proceedings of the Royal Society of London Series B-Biological Sciences, 271, S110-S113.
6. Campbell, T.W. & Ellis, C.K. (2007) Avian and Exotic Animal Hematology and Cytology. Blackwell Publishing Professional, Ames.
7. Carlson, H.C. & Allen, J.R. (1969) Acute inflammatory reaction in chicken skin - blood cellular response. Avian Diseases, 13, 817-833.
8. Cheng, S. & Lamont, S.J. (1988) Genetic analysis of immunocompetence measures in white leghorn chicken line. Poultry Science, 67, 989-995.
9. Cucco, M., Malacarne, G., Ottonelli, R. & Patrone, M. (2006) Repeatability of cell-mediated and innate immunity, and other fitness-related traits, in the Grey Partridge. Canadian Journal of Zoology, 84, 72-79.
10. Felsted, R.L., Egorin, M.J., Leavitt, R.D. & Bachur, N.R. (1977) Recombinations of subunits of Phaseolus vulgaris isolectins. Journal of Biological Chemistry, 252, 2967-2971.
11. Goto, N., Kodama, H., Okada, K. & Fujimoto, Y. (1978) Suppression of phytohemagglutinin skin response in thymectomized chickens. Poultry Science, 57, 246-250.
12. Kennedy, M.W. & Nager, R.G. (2006) The perils and prospects of using phytohaemagglutinin in evolutionary ecology. Trends in Ecology and Evolution, 21, 653-655.
13. Leavitt, R.D., Felsted, R.L. & Bachur, N.R. (1977) Biological and biochemical properties of Phaseolus vulgaris isolectins. Journal of Biological Chemistry, 252, 2961-2966.
14. Lessells, C.M. & Boag, P.T. (1986) Unrepeatable repeatabilities: a common mistake. Auk, 104, 116-121.
15. Licastro, F., Davis, L.J. & Morini, M.C. (1993) Lectins and superantigens - membrane interactions of these compounds with T-lymphocytes affect immune-responses. International Journal of Biochemistry, 25, 845-852.
16. Lochmiller, R.L., Vestey, M.R. & Boren, J.C. (1993) Relationship between protein nutritional-status and immunocompetence in northern Bobwhite chicks. Auk, 110, 503-510.
17. Lucas, A.M. & Jamroz, C. (1961) Atlas of Avian Hematology. United States Department of Agriculture, Washington.
18. Martin, L.B., Han, P., Lewittes, J., Kuhlman, J.R., Klasing, K.C. & Wikelski, M. (2006) Phytohemagglutinin-induced skin swelling in birds: histological support for a classic immunoecological technique. Functional Ecology, 20, 290-299.
19. McCorkle, F., Olah, I. & Glick, B. (1980) Morphology of the phytohemagglutinin-induced cell response in the chickens wattle. Poultry Science, 59, 616-623.
20. Miller, J.B., Hsu, R., Heinrikson, R. & Yachnin, S. (1975) Extensive homology between subunits of phytohemagglutinin mitogenic proteins derived from Phaseolus vulgaris. Proceedings of the National Academy of Sciences of the United States of America, 72, 1388-1391.
21. Mougeot, F. (2008) Ornamental comb colour predicts T-cell-mediated immunity in male red grouse Lagopus lagopus scoticus. Naturwissenschaften, 95, 125-132.
22. Navarro, C., Marzal, A., De Lope, F. & Møller, A.P. (2003) Dynamics of an immune response in house sparrows Passer domesticus in relation to time of day, body condition and blood parasite infection. Oikos, 101, 291-298.
23. Nowell, P.C. (1960) Phytohemagglutinin - an initiator of mitosis in cultures of normal human leukocytes. Cancer Research, 20, 462-466.
24. Owen, J.P. & Clayton, D.H. (2007) Where are the parasites in the PHA response? Trends in Ecology and Evolution, 22, 228-229.
25. Palacios, M.G., Cunnick, J.E., Vleck, D. & Vleck, C.M. (2009) Ontogeny of innate and adaptive immune defense components in free-living tree swallows, Tachycineta bicolor. Developmental and Comparative Immunology, 33, 456-463.
26. Rigas, D.A. & Johnson, E.A. (1964) Studies on phytohemagglutinin of Phaseolus vulgaris and its mitogenicity. Annals of the New York Academy of Sciences, 113, 800-818.
27. Rigas, D.A. & Osgood, E.E. (1955) Purification and properties of the phytohemagglutinin of Phaseolus vulgaris. Journal of Biological Chemistry, 212, 607-615.
28. Rose, N.R. (1994) Thymus function, aging and autoimmunity. Immunology Letters, 40, 225-230.
29. Saino, N., Ambrosini, R., Martinelli, R., Ninni, P. & Møller, A.P. (2003) Gape coloration reliably reflects immunocompetence of barn swallow (Hirundo rustica) nestlings. Behavioral Ecology, 14, 16-22.
30. Smits, J.E., Bortolotti, G.R. & Tella, J.L. (1999) Simplifying the phytohaemagglutinin skin-testing technique in studies of avian immunocompetence. Functional Ecology, 13, 567-572.
31. Tella, J.L., Lemus, J.A., Carrete, M. & Blanco, G. (2008) The PHA test reflects acquired T-cell mediated immunocompetence in birds. PLoS ONE, 3, e3295.
32. Tokuyasu, K., Madden, S.C. & Zeldis, L.J. (1968) Fine structural alterations of interphase nuclei of lymphocytes stimulated to growth activity in vitro. Journal of Cell Biology, 39, 630-660.
33. Vaday, G.G., Franitza, S., Schor, H., Hecht, I., Brill, A., Cahalon, L., Hershkoviz, R. & Lider, O. (2001) Combinatorial signals by inflammatory cytokines and chemokines mediate leukocyte interactions with extracellular matrix. Journal of Leukocyte Biology, 69, 885-892.
34. Yachnin, S., Svenson, R.H., Baron, J.M. & Allen, L.W. (1972) Potentiation of phytohemagglutinin-induced lymphocyte transformation by cell-cell interaction - matrix hypothesis. Cellular Immunology, 3, 569-589.