Substituted spiro [2.3′] oxindolespiro [3.2″]-5,6-dimethoxy- indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 7064-7066

  Ali, Mohamed Ashraf ^a   Ismail, Rusli ^a   Choon, Tan Soo ^a   Yoon, Yeong Keng ^a   Wei, Ang Chee ^a   Pandian, Suresh ^b   Kumar, Raju Suresh ^c   Osman, Hasnah ^c   Manogaran, Elumalai ^d  

^a INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

^b Alwar Pharmacy College   (India)

^c SCHOOL OF PHYSICS   (Malaysia)

^d KARPAGAM UNIVERSITY   (India)

Author keywords

1,3 Dipolar cycloaddition; Acetyl cholinesterase; AChE inhibitor; Alzheimer diseases; Azomethine ylide

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; PYRROLIDINE DERIVATIVE; SPIRO[2.3']OXINDOLESPIRO[3.2''] 5,6 DIMETHOXY 1'' INDANONE 4 (PYRIDYL) 1 N METHYLPYRROLIDINE; SPIRO[2.3']OXINDOLESPIRO[3.2''] 5,6 DIMETHOXY 1'' INDANONE 4 (PYRIDYL) 5 PHENYLPYRROLIDINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CYCLOADDITION; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50;

ALZHEIMER DISEASE; CHOLINESTERASE INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PYRROLIDINES; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78149284340     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.108     Document Type: Article

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