The effects of different rehabilitation strategies on the functional recovery of spinal cord injured rats: An experimental study

Spine

Volumn 35, Issue 23, 2010, Pages

  Robert, Asirvatham Alwin ^a   Ibrahim Al Jadid, Maher Saad ^a   Bin Afif, Sabah ^a   Abdulmohsen Al Sowyed, Abdullah ^b   Al Mubarak, Sultan ^c  

^a Sultan Bin Abdulaziz Humanitarian City ^*  (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

functional recovery; rehabilitation; spinal cord injury

Indexed keywords

CHLORAL HYDRATE;

ANIMAL TISSUE; ARTICLE; BONE PLATE; CONTROLLED STUDY; CONVALESCENCE; DURA MATER; EXPERIMENTAL STUDY; FEMALE; LAMINECTOMY; LOCOMOTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; SWIMMING; TREADMILL EXERCISE;

ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; EXERCISE THERAPY; FEMALE; LAMINECTOMY; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD INJURIES; SWIMMING; THORACIC VERTEBRAE; TREATMENT OUTCOME;

EID: 78149282152     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181e3fc5f     Document Type: Article

References (23)

1. Dumont RJ, Verma S, Okonkwo DO, et al. Acute spinal cord injury. Part II: contemporary pharmacotherapy. Clin Neuropharmacol 2001;24:265-79.
2. Diaz-Ruiz A, Alcaraz-Zubeldia M, Maldonado V, et al. Differential time-course of the increase of antioxidant thiol-defenses in the acute phase after spinal cord injury in rats. Neurosci Lett 2009;452:56-9.
3. Kochanowski J, Malara A, Chudzik W, et al. Pathophysiology and treatment of spinal cord medulla injuries [in Polish]. Neurol Neurochir Pol 1999; 32(suppl 6):91-7.
4. Hausmann ON. Post-traumatic inflammation following spinal cord injury. Spinal Cord 2003;41:369-78.
5. Hall ED. Pharmacological treatment of acute spinal cord injury: how do we build on past success? J Spinal Cord Med 2001;24:142-6.
6. Wells JE, Rice TK, Nuttall RK, et al. An adverse role for matrix metallopro-teinase 12 after spinal cord injury in mice. J Neurosci 2003;23:10107-15.
7. Lankhorst AJ, ter Laak MP, van Laar TJ, et al. Effects of enriched housing on functional recovery after spinal cord contusive injury in the adult rat. J Neurotrauma 2001;18:203-15.
8. Ditunno J, Scivoletto G. Clinical relevance of gait research applied to clinical trials in spinal cord injury. Brain Res Bull 2009;78:35-42.
9. Mehrholz J, Kugler J, Pohl M. Locomotor training for walking after spinal cord injury. Spine 2008;33:E768-77.
10. Fouad K, Pearson K. Restoring walking after spinal cord injury. Prog Neu-robiol 2004;73:107-26.
11. DitunnoJF Jr, Barbeau H, Dobkin BH, et al. Validity of the walking scale for spinal cord injury and other domains of function in a multicenter clinical trial. Neurorehabil Neural Repair 2007;21:539-50.
12. Field-Fote EC, Lindley SD, Sherman AL. Locomotor training approaches for individuals with spinal cord injury: a preliminary report of walking-related outcomes. J Neurol Phys Ther 2005;29:127-37.
13. Norrie BA, Nevett-Duchcherer JM, Gorassini MA. Reduced functional recovery by delaying motor training after spinal cord injury. J Neurophysiol 2005;94:255-64.
14. Wernig A, Muller S, Nanassy A, et al. Laufband therapy based on 'rules of spinal locomotion' is effective in spinal cord injured persons. Eur J Neurosci 1995;7:823-9.
15. Hutchinson KJ, Gomez-Pinilla F, Crowe MJ, et al. Three exercise paradigms differentially improve sensory recovery after spinal cord contusion in rats. Brain 2004;127:1403-14.
16. Magnuson DS, Smith RR, Brown EH, et al. Swimming as a model of task-specific locomotor retraining after spinal cord injury in the rat. Neurorehabil Neural Repair 2009;23:535-45.
17. Al Jadid MS, Robert A, Al-Mubarak S. The efficacy of alpha-tocopherol in functional recovery of spinal cord injured rats: an experimental study. Spinal Cord 2009;47:662-7.
18. Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 1995;12:1-21.
19. Tarlov IM. Spinal cord compression. In: Mechanism of Paralysis and Treatment. Springfield, IL: Charles C Thomas; 1957:147.
20. Wells JE, Hurlbert RJ, Fehlings MG, et al. Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice. Brain 2003; 126:1628-37.
21. Landry E, Frenette J, Guertin PA. Body weight, limb size, and muscular properties of early paraplegic mice. J Neurotrauma 2004;21:1008-16.
22. Primeaux SD, Tong M, Holmes GM. Effects of chronic spinal cord injury on body weight and body composition in rats fed a standard chow diet. Am J Physiol Regul Integr Comp Physiol 2007;293:R1102-9.
23. Petruska JC, Ichiyama RM, Jindrich DL, et al. Changes in motoneuron properties and synaptic inputs related to step training after spinal cord tran-section in rats. J Neurosci 2007;27:4460-71.