Absence of Degradation of Tretinoin When Benzoyl Peroxide is Combined with an Optimized Formulation of Tretinoin Gel (0.05%)

Journal of Clinical and Aesthetic Dermatology

Volumn 3, Issue 10, 2010, Pages 2-

  Del Rosso, James Q ^a   Pillai, Radhakrishnan ^b   Moore, Robert ^b  

^a VALLEY HOSPITAL MEDICAL CENTER   (United States)

^b Dow Pharmaceutical Sciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATRALIN; BENZOYL PEROXIDE; CLINDAMYCIN; RETINOIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DEGRADATION; DRUG ELIMINATION; DRUG FORMULATION; DRUG OXIDATION; GEL;

EID: 78149272653     PISSN: 19412789     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Ghali F, Kang S, Leyden J, Shalita AR, Thiboutot DM. Changing the face of acne therapy. Cutis. 2009;83(2 Suppl):4-15.
2. Haider A, Shaw JC. Treatment of acne vulgaris. JAMA. 2004;292:726-735
3. Yan AC. Current concepts in acne management. Adolesc Med Clin. 2006;17(3):613-637.
4. Sporn, MB, Roberts AB, Goodman DS, eds. The Retinoids-Biology, Chemistry and Medicine. 2nd ed. New York: Raven Press; 1994.
5. Martin B, Meunier C, Montels D, Watts O. Brit J Dermatol. 1998;139(Suppl 52):8-11.
6. Nyirady J, Camelle L, Yusuf M, Migone P, Wisniewski S. The stability of tretinoin in tretinion gel microsphere 0.1%. Cutis. 2002;70:295-298.
7. Ditre CM. Case-based experience with the simultaneous use of a fixed topical antibiotic/benzoyl peroxide combination and a topical retinoid in the optimization of acne management. J Drugs Dermatol. 2009;8(12):1127-1131.
8. Nighland M, Yusuf M, Wisniewski S, et al. The effect of simulated solar UV irradiation on tretinoin in tretinoin gel microsphere 0.1% and tretinoin gel 0.025%. Cutis. 2006;77(5):313-316.
9. Webster G, Cargill I, Quiring J, Vogelson CT, Slade HB. A combined analysis of two randomized clinical studies of tretinoin gel 0.05% for the treatment of acne. Cutis. 2009, 83;146-154.