The functional c.-2G>C variant of the mineralocorticoid receptor modulates blood pressure, renin, and aldosterone levels

Hypertension

Volumn 56, Issue 5, 2010, Pages 995-1002

  Van Leeuwen, Nienke ^a   Caprio, Massimiliano ^b   Blaya, Carolina ^c   Fumeron, Frédéric ^d,e   Sartorato, Paola ^f   Ronconi, Vanessa ^g   Giacchetti, Gilberta ^g   Mantero, Franco ^f   Fernandes Rosa, Fabio L ^d,e   Simian, Christophe ^h   Peyrard, Sévrine ^h   Zitman, Frans G ⁱ   Penninx, Brenda W J H ^i,j   De Kloet, E Ron ^a   Azizi, Michel ^e,h   Jeunemaitre, Xavier ^d,e,h   Derijk, Roel H ^a,i   Zennaro, Maria Christina ^d,e,h  

^a LEIDEN UNIVERSITY   (Netherlands)

^b IRCCS SAN RAFFAELE PISANA   (Italy)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d INSERM   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f UNIVERSITY OF PADOVA   (Italy)

^g UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^h HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

ⁱ LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^j VU UNIVERSITY MEDICAL CENTER   (Netherlands)

more..

Author keywords

aldosterone; hypertension; mineralocorticoid; nuclear receptor; sodium balance

Indexed keywords

ALDOSTERONE; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIURETIC AGENT; MINERALOCORTICOID RECEPTOR; RENIN;

ADULT; ALDOSTERONE BLOOD LEVEL; ALLELE; ANIMAL CELL; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DISEASE SEVERITY; ESSENTIAL HYPERTENSION; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; NONHUMAN; POTASSIUM RESTRICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM RESTRICTION; SYSTOLIC BLOOD PRESSURE; TRANSCRIPTION INITIATION; ADOLESCENT; AGED; BLOOD; BLOOD PRESSURE; CROSSOVER PROCEDURE; GENETICS; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AGED; ALDOSTERONE; ALLELES; BLOOD PRESSURE; CROSS-OVER STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, MINERALOCORTICOID; RENIN; RENIN-ANGIOTENSIN SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78149270394     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.155630     Document Type: Article

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