In vitro selection of highly darunavir-resistant and replication-competent HIV-1 variants by using a mixture of clinical HIV-1 isolates resistant to multiple conventional protease inhibitors

Journal of Virology

Volumn 84, Issue 22, 2010, Pages 11961-11969

  Koh, Yasuhiro ^a   Amano, Masayuki ^a   Towata, Tomomi ^a   Danish, Matthew ^a   Leshchenko Yashchuk, Sofiya ^b   Das, Debananda ^c   Nakayama, Maki ^a   Tojo, Yasushi ^a   Ghosh, Arun K ^b   Mitsuya, Hiroaki ^a,c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b PURDUE UNIVERSITY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPRENAVIR; ATAZANAVIR; CYCLOPHILIN; DARUNAVIR; INDINAVIR; LOPINAVIR; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; TIPRANAVIR;

AMINO ACID SUBSTITUTION; ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; CONTROLLED STUDY; GENETIC VARIABILITY; HOMOLOGOUS RECOMBINATION; HUMAN IMMUNODEFICIENCY VIRUS 1; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRION; VIRUS MUTATION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; RITONAVIR; SEQUENCE ALIGNMENT; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78049524808     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00967-10     Document Type: Article

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